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Dementia
Is senile dementia hereditary?
The disease referred to as dementia mainly refers to Alzheimer's disease. Only a very small number of cases are hereditary, where patients have a certain family history caused by genetic mutations, thus having some hereditary traits. However, the vast majority of Alzheimer's cases are sporadic, unrelated to genetic mutations, and these sporadic cases are not hereditary, so there is no need to worry about transmitting it to offspring. Nevertheless, it is important to note that, with the progression of population aging, the incidence of this disease remains relatively high, especially for those over the age of 65, who need to pay close attention to this disease. If a patient exhibits a decline in memory function, do not assume it is just forgetfulness; it is crucial to visit a hospital for diagnosis and timely treatment.
What to do about senile dementia?
For patients with dementia, if the diagnosis is confirmed, the recommended treatment is as follows: First, it is very important to pay attention to nursing care. Patients with dementia often get lost, which can lead to a series of dangers, so it is necessary to take good care of them to prevent getting lost. Secondly, for the improvement of cognitive functions, it is recommended to use some cholinesterase inhibitors, which can increase the level of acetylcholine in the brain and improve the patient's cognitive functions to a certain extent. Third, symptomatic treatment should also be provided. Since patients with dementia often exhibit psychiatric symptoms, such as visual and auditory hallucinations, appropriate antipsychotic medications can be used for treatment. (Please use medication under the guidance of a professional physician.)
Methods for Examining Dementia in the Elderly
The examination of dementia mainly includes the following aspects. First, it is to determine whether the patient has cognitive impairment, because in the early stages of dementia this impairment is often mild, primarily in recent memory, with other aspects not yet obvious. Early screening can use some cognitive evaluation scales, such as the Mini-Mental State Examination or the Montreal Cognitive Assessment, chosen according to the patient's cultural level. Second, imaging examination, commonly using brain MRI, can reveal significant signs of dementia such as deepened brain sulci, narrowed gyri, and widened lateral fissures, indicating brain atrophy. Third, genetic testing for the APOE gene, which may be related to dementia. Possession of this gene may increase the likelihood of developing dementia in the future, serving as an auxiliary diagnostic measure.
Causes of Dementia
At present, the specific causes and mechanisms of Alzheimer's disease are not very clear, but they are mainly divided into two categories. The first category is hereditary, where some Alzheimer's disease cases have a clear family history and involve some genetic mutations. These genetic mutations lead to the deposition of abnormal proteins within neurons, causing irreversible neuronal death, which is the main reason for familial Alzheimer’s disease. The second category is sporadic Alzheimer’s disease, for which no clear pathogenesis has been identified. Research suggests that factors such as oxidative stress, trauma, cerebrovascular disease, cerebral ischemia, and other factors, including metabolic conditions leading to dementia, are related to the occurrence of sporadic Alzheimer's disease. Therefore, the causes of Alzheimer’s disease include two main categories: the first is caused by genetic mutations, and the second is caused by various adverse factors leading to neuronal death.
Is spinal bifida prone to dementia?
Spina bifida is a common congenital malformation caused by incomplete closure of the vertebral canal during embryonic development. If the spina bifida is occult, it does not affect anything and does not cause dementia. If it is overt spina bifida, it can be diagnosed through physical examination, and confirmed with radiographic examination, CT, or MRI. Typically, the patient has a swelling along the midline of the back, which grows as they age. The cystic tension increases when the child cries, and may be accompanied by varying degrees of flaccid paralysis of the lower limbs and incontinence. Occult spina bifida generally has no symptoms and does not require intervention. However, overt spina bifida is best treated surgically, or if the occult spina bifida is accompanied by spinal cord tethering, then surgical treatment is recommended as it would be for all cases of overt spina bifida. In cases where the cyst wall is very thin and ruptured, emergency surgery is necessary and can be curative. For other cases, surgery within one to three months is optimal to prevent aggravation of the condition due to cyst rupture. Generally, adult patients with stable conditions in recent years may not need surgery.
How is dementia diagnosed in the elderly?
Alzheimer's disease is a degenerative disease of the nervous system. The diagnosis of this disease mainly relies on the clinical manifestations of the patient, as well as some corresponding scales and some corresponding imaging examinations. In terms of examinations, it is necessary to check some neurofunctional scales, mainly cognitive function scales, common scales include some MMSE scales, and some MoCA scales. These scales are very important for diagnosing this disease. In addition, some imaging examinations need to be improved, mainly including cranial magnetic resonance imaging examinations. Cranial MRI can reveal atrophy in the patient's temporal lobe, hippocampus, and other areas, which also have an important reference value for the diagnosis of the disease. Moreover, an electroencephalogram can be performed to see some mild abnormalities, and lumbar puncture tests can also reveal some abnormally increased protein deposits.
Alzheimer's disease is also called dementia.
Alzheimer's disease, also known as dementia in the elderly, was first identified abroad and thus named after the discoverer, Alzheimer. It is one of the most common neurodegenerative diseases in neurology, with a very high incidence among people over 65 in China and worldwide. The disease mainly affects patients' cognitive functions. Initially, patients do not meet the criteria for dementia and primarily exhibit a decline in memory. As the disease progresses, the decline in memory worsens, and patients begin to forget both recent and past events. Additionally, they may experience impairments in visuospatial abilities, judgment, comprehension, and learning capabilities. In the later stages, psychiatric symptoms and personality changes may appear, such as visual hallucinations, shouting, and gesturing wildly, among various other clinical manifestations.
What is the greatest fear in Alzheimer's disease?
Dementia in the elderly is a common neurodegenerative disease worldwide. It is a clinical syndrome caused by the irreversible death of brain neurons due to various factors. Initially, the main symptom in patients is impaired memory function, which at this stage does not significantly affect work and life, and is not overly concerning. As the disease progresses, the cognitive functions of the elderly, including visuospatial skills, calculation abilities, and executive functions, are notably impaired. Changes in personality and behavior also occur. What is most feared in dementia? It is particularly concerning when elderly individuals go out on their own and then cannot find their way home, leading to situations where they may become lost. If the elderly are unable to find adequate food outdoors, or if the weather is too cold or too hot, their life safety can be severely threatened. Additionally, dementia patients might inadvertently turn on the gas at home and forget to turn it off, which can easily lead to accidents. These are the most feared incidents related to dementia in the elderly.
Can senile dementia be cured?
Dementia in the elderly is a clinical syndrome caused by the irreversible death of neurons. So far, the mechanism of the disease is not particularly clear, making it very difficult to cure dementia completely. However, there are some corresponding treatment methods that can delay the progression of the disease and improve the quality of life of patients as much as possible. These treatments mainly include exercise therapy, which involves getting patients to participate in appropriate physical activities that can promote cognitive development. In addition, letting patients listen to music more often, interact more with others, and continue learning can also delay the progression of aging. Furthermore, there are some medications that can improve the symptoms of dementia. Currently, the most commonly used worldwide are acetylcholinesterase inhibitors, which can increase the levels of acetylcholine and thereby improve cognitive function to some extent and slow the progression of the disease. Additionally, if elderly individuals exhibit some psychiatric symptoms, they can also be given some atypical antipsychotic medications to alleviate the condition.
Is senile dementia hereditary?
Dementia primarily refers to Alzheimer's disease, which mainly has two types: The first type is sporadic Alzheimer's disease, which does not have a clear familial history. It is caused by the degeneration and death of neurons due to various reasons, leading to certain clinical symptoms. This type of sporadic dementia does not have a genetic predisposition. The other type of dementia has a clear family history, where patients typically exhibit mutations in the APP gene, leading to increased secretion, which in turn causes the death of neurons and results in the symptoms of dementia. This familial type of dementia has a genetic predisposition. Dementia is a common condition in neurology and is the most common neurodegenerative disease. Currently, there are no effective treatments available. Family members must pay attention to caregiving, and patients can take cholinesterase inhibitors, which can improve symptoms to a certain extent.