Alzheimer's disease is also called dementia.

Written by Zhang Hui
Neurology
Updated on September 22, 2024
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Alzheimer's disease, also known as dementia in the elderly, was first identified abroad and thus named after the discoverer, Alzheimer. It is one of the most common neurodegenerative diseases in neurology, with a very high incidence among people over 65 in China and worldwide. The disease mainly affects patients' cognitive functions. Initially, patients do not meet the criteria for dementia and primarily exhibit a decline in memory. As the disease progresses, the decline in memory worsens, and patients begin to forget both recent and past events. Additionally, they may experience impairments in visuospatial abilities, judgment, comprehension, and learning capabilities. In the later stages, psychiatric symptoms and personality changes may appear, such as visual hallucinations, shouting, and gesturing wildly, among various other clinical manifestations.

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Written by Zhang Hui
Neurology
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Determination of Senile Dementia

The assessment of dementia primarily encompasses three aspects: The first aspect mainly involves relevant neurological scales, which can scientifically and effectively measure the cognitive functions of elderly patients. These scales include the MSE (Mini-Mental State Examination) and the MoCA (Montreal Cognitive Assessment). The second aspect of the assessment involves some imaging tests, mainly cranial MRI scans. Cranial MRI can determine if there is brain atrophy in the elderly and examine for any related lesions in the temporal lobes and hippocampi. The third major aspect involves the analysis of cerebrospinal fluid, assessing the levels of amyloid proteins, which also play an important role in the assessment of dementia. In summary, the assessment of dementia primarily involves evaluations using neurological scales, cranial MRI, and cerebrospinal fluid analysis.

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Written by Zhang Hui
Neurology
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What is the greatest fear in Alzheimer's disease?

Dementia in the elderly is a common neurodegenerative disease worldwide. It is a clinical syndrome caused by the irreversible death of brain neurons due to various factors. Initially, the main symptom in patients is impaired memory function, which at this stage does not significantly affect work and life, and is not overly concerning. As the disease progresses, the cognitive functions of the elderly, including visuospatial skills, calculation abilities, and executive functions, are notably impaired. Changes in personality and behavior also occur. What is most feared in dementia? It is particularly concerning when elderly individuals go out on their own and then cannot find their way home, leading to situations where they may become lost. If the elderly are unable to find adequate food outdoors, or if the weather is too cold or too hot, their life safety can be severely threatened. Additionally, dementia patients might inadvertently turn on the gas at home and forget to turn it off, which can easily lead to accidents. These are the most feared incidents related to dementia in the elderly.

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Written by Zhang Hui
Neurology
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How is dementia diagnosed in the elderly?

Alzheimer's disease is a degenerative disease of the nervous system. The diagnosis of this disease mainly relies on the clinical manifestations of the patient, as well as some corresponding scales and some corresponding imaging examinations. In terms of examinations, it is necessary to check some neurofunctional scales, mainly cognitive function scales, common scales include some MMSE scales, and some MoCA scales. These scales are very important for diagnosing this disease. In addition, some imaging examinations need to be improved, mainly including cranial magnetic resonance imaging examinations. Cranial MRI can reveal atrophy in the patient's temporal lobe, hippocampus, and other areas, which also have an important reference value for the diagnosis of the disease. Moreover, an electroencephalogram can be performed to see some mild abnormalities, and lumbar puncture tests can also reveal some abnormally increased protein deposits.

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Written by Zhang Hui
Neurology
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early signs of dementia

Dementia in the elderly, mainly referring to Alzheimer's disease, is primarily characterized by a significant decline in the patient's memory and learning abilities. Of course, there are some prodromal symptoms before the onset of dementia. For example, patients might show no clinical signs of cognitive impairment or only display very slight memory decline. Patients might exhibit mild impairment in memory, a decrease in the ability to learn and retain new information, and mild impairments in other cognitive areas such as attention, executive function, language skills, and visuospatial abilities. However, these impairments are very slight and can go unnoticed by family members. Moreover, these mild impairments do not affect the patient's basic daily life abilities and do not reach the level of dementia. Patients can live independently and manage their routine daily tasks, which are mainly some of the early signs of dementia.

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Written by Tang Bo
Neurology
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Mild manifestations of senile dementia

Mild dementia, especially in its early stages, often goes unnoticed by family members. The initial symptoms generally include being particularly forgetful. This particularly affects short-term memory; for example, a person might repeat what was just said or be repeatedly clumsy in daily tasks, sometimes losing keys or forgetting to turn off the stove while cooking. This might seem like a lack of concentration, but in reality, it is due to forgetfulness. Emotionally, individuals who were once lively might become indifferent or detached, sometimes showing signs of excitement or agitation. Behaviorally, there can be changes, such as previously generous individuals becoming stingy. Interests and hobbies that were once loved may no longer hold appeal, and individuals may become lethargic and less concerned with cleanliness and personal appearance.