Is senile dementia hereditary?

Written by Zhang Hui
Neurology
Updated on September 14, 2024
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Dementia primarily refers to Alzheimer's disease, which mainly has two types: The first type is sporadic Alzheimer's disease, which does not have a clear familial history. It is caused by the degeneration and death of neurons due to various reasons, leading to certain clinical symptoms. This type of sporadic dementia does not have a genetic predisposition. The other type of dementia has a clear family history, where patients typically exhibit mutations in the APP gene, leading to increased secretion, which in turn causes the death of neurons and results in the symptoms of dementia. This familial type of dementia has a genetic predisposition. Dementia is a common condition in neurology and is the most common neurodegenerative disease. Currently, there are no effective treatments available. Family members must pay attention to caregiving, and patients can take cholinesterase inhibitors, which can improve symptoms to a certain extent.

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Written by Zhang Hui
Neurology
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Causes of Alzheimer's Disease in the Elderly

The causes of dementia in the elderly are not currently completely clear. Dementia in the elderly is mainly divided into familial and sporadic types. Familial dementia shows autosomal dominant inheritance, which is caused by a gene mutation on chromosome 21 leading to the accumulation of some toxins, resulting in the death of neurons and causing dementia fundamentally due to genetic mutations. However, most cases of dementia are sporadic and do not have a clear family history. The mechanisms and reasons for disease onset are not particularly clear. Some believe that abnormalities in cerebral vascular function may lead to neuronal cell functional disorders, resulting in decreased ability to clear certain cell toxins, thus leading to neuronal apoptosis and death, and consequently impaired cognitive functions. In addition, factors such as oxidative stress, inflammatory mechanisms, excessive fatigue, and emergency stress may also cause cell death. Overall, the causes of dementia in the elderly are not particularly clear.

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Written by Zhang Hui
Neurology
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How to alleviate senile dementia?

Dementia brings a heavy burden to both the patient and their family, severely affecting the quality of life. Fundamentally, there is no particularly effective treatment for this disease. To achieve relief, the following measures are recommended: Firstly, it is generally necessary for the patient to take medication for treatment. Commonly used medications include cholinesterase inhibitors, which can increase the content of acetylcholine in the brain and can to some extent delay the progression of the disease. In addition, one can also take some NMDA receptor antagonists to improve dementia. Secondly, encourage the elderly to learn more and read more, which can increase knowledge reserves and delay progression. Thirdly, it is essential to encourage the elderly to go out and interact with others, and of course, precautions should be taken to prevent them from getting lost. In addition, they should engage in appropriate aerobic exercise. (Specific medication use should be conducted under the guidance of a doctor)

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Written by Zhang Hui
Neurology
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What is the full name of dementia?

Senile dementia mainly refers to Alzheimer's disease, a condition with a relatively high incidence rate among the elderly population, and it is the most common neurodegenerative disease. The specific causes and mechanisms of this disease are not particularly clear. Under the influence of various factors, degeneration and death of the temporal lobe, hippocampus, and neurons occur, leading to a series of clinical manifestations. Initially, it mainly manifests as a decline in recent memory function, often forgetting recent events. As the disease progresses, there is a decline in calculating ability and judgment, significant spatial dysfunction, personality changes, and psychiatric symptoms.

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Written by Zhang Hui
Neurology
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How is Alzheimer's disease treated?

Senile dementia, also known as Alzheimer's disease, is the most common neurodegenerative disease worldwide. The pathogenesis of this disease is not particularly clear so far and may be related to genetic and environmental factors. Multiple factors act on neurons causing irreversible and progressive death of neuronal cells. Currently, the treatment of this disease mainly includes two aspects. The first aspect is general treatment, mainly including family care. Family members must pay attention to the care of the patient, prevent the patient from accidentally wandering off, prevent the patient from falling, and prevent some accidents that cause injuries. In addition, it is important for the patient to listen to music, interact with others, and exercise more, all of which can delay the progression of senile dementia. The second aspect is pharmacological treatment, mainly using drugs that inhibit the reduction of acetylcholine. These drugs can increase the content of acetylcholine and improve the cognitive functions of patients to a certain extent, but so far, these treatments cannot reverse senile dementia.

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Written by Zhang Hui
Neurology
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Alzheimer's disease is also called dementia.

Alzheimer's disease, also known as dementia in the elderly, was first identified abroad and thus named after the discoverer, Alzheimer. It is one of the most common neurodegenerative diseases in neurology, with a very high incidence among people over 65 in China and worldwide. The disease mainly affects patients' cognitive functions. Initially, patients do not meet the criteria for dementia and primarily exhibit a decline in memory. As the disease progresses, the decline in memory worsens, and patients begin to forget both recent and past events. Additionally, they may experience impairments in visuospatial abilities, judgment, comprehension, and learning capabilities. In the later stages, psychiatric symptoms and personality changes may appear, such as visual hallucinations, shouting, and gesturing wildly, among various other clinical manifestations.