Can senile dementia be cured?

Written by Zhang Hui
Neurology
Updated on September 16, 2024
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Dementia in the elderly is a clinical syndrome caused by the irreversible death of neurons. So far, the mechanism of the disease is not particularly clear, making it very difficult to cure dementia completely. However, there are some corresponding treatment methods that can delay the progression of the disease and improve the quality of life of patients as much as possible. These treatments mainly include exercise therapy, which involves getting patients to participate in appropriate physical activities that can promote cognitive development. In addition, letting patients listen to music more often, interact more with others, and continue learning can also delay the progression of aging. Furthermore, there are some medications that can improve the symptoms of dementia. Currently, the most commonly used worldwide are acetylcholinesterase inhibitors, which can increase the levels of acetylcholine and thereby improve cognitive function to some extent and slow the progression of the disease. Additionally, if elderly individuals exhibit some psychiatric symptoms, they can also be given some atypical antipsychotic medications to alleviate the condition.

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Written by Tang Li Li
Neurology
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Methods for Examining Dementia in the Elderly

The examination of dementia mainly includes the following aspects. First, it is to determine whether the patient has cognitive impairment, because in the early stages of dementia this impairment is often mild, primarily in recent memory, with other aspects not yet obvious. Early screening can use some cognitive evaluation scales, such as the Mini-Mental State Examination or the Montreal Cognitive Assessment, chosen according to the patient's cultural level. Second, imaging examination, commonly using brain MRI, can reveal significant signs of dementia such as deepened brain sulci, narrowed gyri, and widened lateral fissures, indicating brain atrophy. Third, genetic testing for the APOE gene, which may be related to dementia. Possession of this gene may increase the likelihood of developing dementia in the future, serving as an auxiliary diagnostic measure.

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Written by Zhang Hui
Neurology
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Determination of Senile Dementia

The assessment of dementia primarily encompasses three aspects: The first aspect mainly involves relevant neurological scales, which can scientifically and effectively measure the cognitive functions of elderly patients. These scales include the MSE (Mini-Mental State Examination) and the MoCA (Montreal Cognitive Assessment). The second aspect of the assessment involves some imaging tests, mainly cranial MRI scans. Cranial MRI can determine if there is brain atrophy in the elderly and examine for any related lesions in the temporal lobes and hippocampi. The third major aspect involves the analysis of cerebrospinal fluid, assessing the levels of amyloid proteins, which also play an important role in the assessment of dementia. In summary, the assessment of dementia primarily involves evaluations using neurological scales, cranial MRI, and cerebrospinal fluid analysis.

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Written by Zhang Hui
Neurology
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Is senile dementia hereditary?

The disease referred to as dementia mainly refers to Alzheimer's disease. Only a very small number of cases are hereditary, where patients have a certain family history caused by genetic mutations, thus having some hereditary traits. However, the vast majority of Alzheimer's cases are sporadic, unrelated to genetic mutations, and these sporadic cases are not hereditary, so there is no need to worry about transmitting it to offspring. Nevertheless, it is important to note that, with the progression of population aging, the incidence of this disease remains relatively high, especially for those over the age of 65, who need to pay close attention to this disease. If a patient exhibits a decline in memory function, do not assume it is just forgetfulness; it is crucial to visit a hospital for diagnosis and timely treatment.

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Written by Zhang Hui
Neurology
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Is senile dementia hereditary?

Dementia primarily refers to Alzheimer's disease, which mainly has two types: The first type is sporadic Alzheimer's disease, which does not have a clear familial history. It is caused by the degeneration and death of neurons due to various reasons, leading to certain clinical symptoms. This type of sporadic dementia does not have a genetic predisposition. The other type of dementia has a clear family history, where patients typically exhibit mutations in the APP gene, leading to increased secretion, which in turn causes the death of neurons and results in the symptoms of dementia. This familial type of dementia has a genetic predisposition. Dementia is a common condition in neurology and is the most common neurodegenerative disease. Currently, there are no effective treatments available. Family members must pay attention to caregiving, and patients can take cholinesterase inhibitors, which can improve symptoms to a certain extent.

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Written by Zhang Hui
Neurology
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probability of senile dementia

Dementia primarily refers to Alzheimer's disease, which has a relatively high incidence rate. In China, among the elderly population over 65 years old, approximately 3% to 7% are affected; this rate can rise to over 20% among those over 85 years old. Suffering from dementia places a heavy burden on the patient, their family, and society. Initially, patients with dementia will experience a decline in memory function. As the condition progresses, there will be a decline in various cognitive functions. For example, spatial dysfunction might occur, such as getting lost on the way home, personality changes, and the emergence of psychiatric symptoms and other clinical manifestations.