Typical skin manifestations of systemic lupus erythematosus

Written by Yang Ya Meng
Rheumatology
Updated on December 23, 2024
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The most typical skin rashes of systemic lupus erythematosus are called butterfly rash and discoid rash. The so-called butterfly rash is a rash on both sides of the nostrils, resembling the wings of a butterfly, and the so-called discoid rash is a circular, disc-shaped rash on the facial area. At the same time, patients with systemic lupus erythematosus may also experience reticular purpura or vasculitic rashes like those of end-finger vasculitis, all of which are typical manifestations of skin rashes in patients with systemic lupus erythematosus.

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Written by Li Jing
Rheumatology
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What department should I go to for systemic lupus erythematosus?

Systemic lupus erythematosus is an autoimmune disease and can test positive for multiple antibodies, affecting various organs throughout the body. Its primary manifestations are damage to the skin, mucous membranes, and kidneys. The most common and characteristic symptom is the butterfly rash on the skin and mucous membranes. Some people may also experience facial rashes, blisters, and even chilblain-like changes. Such skin changes should be viewed with caution. Additionally, symptoms can include general weakness and low-grade fever. This condition requires formal treatment from a rheumatology and immunology department.

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Written by Yang Ya Meng
Rheumatology
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What causes systemic lupus erythematosus?

Systemic lupus erythematosus mainly has four major causes: The first is related to the environment. Long-term exposure to sunlight, or living in a humid environment, may trigger the onset of systemic lupus erythematosus. Secondly, there is a certain genetic predisposition to systemic lupus erythematosus. If the parents have systemic lupus erythematosus, the probability of their offspring developing the disease is higher. Thirdly, systemic lupus erythematosus is also related to estrogen, which is why, clinically, lupus is more commonly seen in women of childbearing age and less often in men. Systemic lupus erythematosus is also associated with some specific infections, such as bacterial or viral infections, which may trigger a lupus flare-up.

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Written by Yang Ya Meng
Rheumatology
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Can people with systemic lupus erythematosus have children?

Patients with systemic lupus erythematosus can have children, but only if they are taking less than one and a half steroids and less than two hydroxychloroquine tablets. Additionally, they must be closely monitored throughout the early, middle, and late stages of pregnancy, and regularly consult with both obstetricians and rheumatologists to discuss any necessary adjustments in treatment. This is because pregnancy is a high-risk factor for triggering lupus activity, with the disease often relapsing during the first six weeks of pregnancy and the six weeks following childbirth. (Medications should be used under the guidance of a physician.)

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Written by Yang Ya Meng
Rheumatology
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What to do if systemic lupus erythematosus causes a fever?

Patients with systemic lupus erythematosus (SLE) who develop a fever first need to discern whether the fever is due to immune-related fever caused by the activity of the disease or an infectious fever due to weakened immunity from long-term use of steroids and immunosuppressants. If the fever is caused by lupus activity, then it is necessary to increase the dosage of corticosteroids in treatment. If the fever is due to an infection, a full course of anti-infection treatment is needed. The anti-infection regimen may even need to include treatments with antibacterial, antifungal, and antiviral medications. (Please follow professional medical advice for medication use, and do not self-medicate.)

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Written by Li Jing
Rheumatology
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Can systemic lupus erythematosus be cured?

Systemic lupus erythematosus (SLE) kidney is a chronic autoimmune disease with multi-organ damage that occurs systemically. This disease is common in women of childbearing age and is most frequently characterized by facial rashes. It can also present with fever, hair loss, and even edema of both lower limbs and hypoalbuminemia. As an autoimmune disease, it cannot be cured and can only be managed with medications. Treatment aims to stabilize the condition and gradually reduce the medication dosage to the minimum necessary to maintain the condition and prevent it from becoming active, thus delaying damage to other organs. Systemic lupus erythematosus involves multiple systems, with the kidneys being the most susceptible, requiring formal medical treatment to prevent complications in the organs.