What causes systemic lupus erythematosus?

Written by Yang Ya Meng
Rheumatology
Updated on October 25, 2024
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Systemic lupus erythematosus mainly has four major causes: The first is related to the environment. Long-term exposure to sunlight, or living in a humid environment, may trigger the onset of systemic lupus erythematosus. Secondly, there is a certain genetic predisposition to systemic lupus erythematosus. If the parents have systemic lupus erythematosus, the probability of their offspring developing the disease is higher. Thirdly, systemic lupus erythematosus is also related to estrogen, which is why, clinically, lupus is more commonly seen in women of childbearing age and less often in men. Systemic lupus erythematosus is also associated with some specific infections, such as bacterial or viral infections, which may trigger a lupus flare-up.

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Written by Li Jing
Rheumatology
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What should I do about hair loss from systemic lupus erythematosus?

First, systemic lupus erythematosus is an autoimmune disease characterized by multi-organ and multi-systemic damage, a systemic autoimmune disorder. It cannot be completely cured, but its symptoms can be managed and the progression of the disease can be controlled through medication. The main clinical manifestations include facial rashes, photosensitivity, Raynaud's phenomenon, fever, hair loss, etc. Therefore, in the treatment process of patients with systemic lupus erythematosus, if there is an increase in hair loss, or if other symptoms such as photosensitivity and hair loss occur, it may be considered that the disease is active or recurring. At this time, it is necessary to go to the hospital for comprehensive tests such as blood routine, erythrocyte sedimentation rate (ESR), complement levels, and autoimmune antibodies to assess the condition. If the disease is active or recurring, an adjustment in the dosage of the treatment medications may be necessary.

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Written by Li Jing
Rheumatology
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Systemic lupus erythematosus is not contagious.

Systemic lupus erythematosus is a chronic autoimmune disease that can damage multiple systems and affect multiple organs. Its occurrence is related to genetics, environmental pollution, hormonal levels, and infections. It is classified as an autoimmune disease and is not infectious or contagious. Once diagnosed with systemic lupus erythematosus, it is important to thoroughly complete related examinations and assess the activity level of the disease, as treatment plans vary accordingly. Therefore, for patients with systemic lupus erythematosus, there is no need to worry about it being contagious. However, there is a hereditary tendency, meaning if the parents have it, the likelihood of their children developing the disease is significantly higher than others.

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Written by Yang Ya Meng
Rheumatology
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Can people with systemic lupus erythematosus eat mutton?

Patients with systemic lupus erythematosus should not eat lamb. This is because foods like lamb and dog meat are overly warming and nourishing, and they may trigger a relapse of the disease. Patients should also consume less of the foods that are photosensitive, such as celery, coriander, and mushrooms. Moreover, since lupus is an autoimmune disease and patients tend to have hypersensitive constitutions, they should also reduce their intake of seafood such as shrimp and crab. Additionally, patients should avoid certain warming and nourishing foods like longan. At the same time, they can supplement their diet with high-quality, low-protein foods like egg whites and fish.

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Written by Yang Ya Meng
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Systemic Lupus Erythematosus Clinical Manifestations

The clinical manifestations of systemic lupus erythematosus are diverse and variable. The primary symptoms involve the bones, joints, and muscles, with joint pain being a common presentation. The second major area affected is the skin and mucous membranes, where the most common symptoms are symmetrical butterfly-shaped erythema and discoid erythema on the face. Some patients experience kidney involvement, primarily presenting as significant proteinuria, hematuria, and cylindrical urine. Pulmonary involvement is also common in some patients, often manifesting as pleurisy. The digestive system can also be affected, typically presenting as abdominal pain. The hematological system is a very common site of involvement in lupus, mainly indicated by routine blood tests showing decreases in white blood cells and platelets.

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Written by Li Jing
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Systemic Lupus Erythematosus Symptom Chart

Firstly, systemic lupus erythematosus is a multi-system, multi-organ autoimmune disease that cannot be cured but can only be controlled with medication to slow the progression of the disease and prevent complications. Clinical manifestations are diverse, with most early symptoms typically being atypical, and sometimes not presenting any discomfort at all. Some individuals may experience acute onset, which can include high fever, progressive decline in platelets, and even progressive anemia, all characteristic of the acute phase. Other common symptoms include fever, skin erythema, and even ischemia of the extremities. Some people may experience joint pain, mainly in the finger joints and knee joints, as well as swelling of the lower limbs, chest tightness, and decreased exercise tolerance, which are more typical manifestations.