Systemic lupus erythematosus is an autoimmune disease and can test positive for multiple antibodies, affecting various organs throughout the body. Its primary manifestations are damage to the skin, mucous membranes, and kidneys. The most common and characteristic symptom is the butterfly rash on the skin and mucous membranes. Some people may also experience facial rashes, blisters, and even chilblain-like changes. Such skin changes should be viewed with caution. Additionally, symptoms can include general weakness and low-grade fever. This condition requires formal treatment from a rheumatology and immunology department.