If patients with systemic lupus erythematosus develop a fever, it is first necessary to determine whether the fever is caused by poor control of systemic lupus erythematosus, leading to an immune-related fever, or if it is due to the patient's long-term use of corticosteroids and immunosuppressants, resulting in decreased resistance and an acute infection, thus causing the fever.

If the fever is immune-related, it will be necessary to strengthen treatment with corticosteroids and immunosuppressants. If the fever is due to an infection, regular anti-infection treatment will be required, which sometimes includes antifungal, antibacterial, and antiviral therapies.

(The use of medications should be carried out under the guidance of a doctor)