Systemic lupus erythematosus symptoms

Written by Yang Ya Meng
Rheumatology
Updated on November 24, 2024
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The symptoms of systemic lupus erythematosus mainly include fever, oral ulcers, facial erythema, including discoid and malar rash, photosensitivity, joint pain, polyserositis, including pleural effusion and pericardial effusion, as well as kidney involvement. The main manifestations are positive urinary protein, hematuria, and casts in the urine. Severe cases may have neurological involvement, presenting as epilepsy, mental disorders, or altered consciousness. Blood tests in these patients can further reveal positive ANA, anti-double-stranded DNA, and anti-Sm antibodies, as well as low complement levels. These are the related symptoms of systemic lupus erythematosus.

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Written by Li Jing
Rheumatology
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Systemic lupus erythematosus is not contagious.

Firstly, systemic lupus erythematosus is an autoimmune disease with an unclear cause. It can affect multiple organs including the heart, lungs, and kidneys. It is classified as an autoimmune disease and not a contagious one, so there is no need to worry about it spreading. However, this condition does have a certain genetic predisposition. For instance, if parents have systemic lupus erythematosus, then their offspring have a relatively higher chance of developing the condition compared to families without a history of the disease. Being an autoimmune disease, it cannot be cured but can only be managed with medications such as corticosteroids to control the progression of the disease. Therefore, during the course of steroid treatment, it is vital to prevent infections. Finally, it is important to emphasize once again that systemic lupus erythematosus is not contagious and does not pose a risk of transmission, so everyone can be reassured.

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Written by Li Jing
Rheumatology
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What should be noted for systemic lupus erythematosus?

Systemic lupus erythematosus is an autoimmune disease and a chronic disease that damages multiple systems. It cannot be cured, only controlled by medication to manage symptoms, delay complications, and reduce mortality; these are the primary treatment goals. Therefore, during treatment, several aspects must be carefully considered: First, avoid prolonged sun exposure, chemical irritants, being overly cold or fatigued, as these can trigger the condition. Women should also avoid taking oral contraceptives. Second, do not be misled by advertisements and promotions; always seek treatment in reputable hospitals to prevent complications. Third, during treatment, always keep in contact with your attending physician. Do not adjust or reduce your medication on your own, as this can exacerbate the disease and greatly increase the risk of relapse.

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Written by Li Jing
Rheumatology
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What causes systemic lupus erythematosus?

Firstly, systemic lupus erythematosus belongs to autoimmune diseases and is a multisystemic autoimmune disorder. It is a chronic disease that cannot be cured. It can only be managed through medication to control the progression of the disease, prevent relapses, delay damage to other organs, and prevent complications. This is the overall principle of treatment. Its cause is currently unclear. It is only related to factors such as environmental pollution, viral infections, genetics, and hormones, according to expert research. However, there is no specific definitive cause identified.

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Written by Yang Ya Meng
Rheumatology
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Is systemic lupus erythematosus serious?

Systemic lupus erythematosus (SLE) can vary in severity. The main criterion for determining whether it is mild or severe is to check whether SLE has involved important visceral organs, such as the lungs, the heart, and most commonly, the kidneys, as well as the most severe form, neuropsychiatric lupus. If a patient shows involvement of the aforementioned visceral systems, then lupus is considered to be relatively severe, and may sometimes even threaten the patient’s life. However, if lupus does not involve the visceral systems, it is considered to be mild.

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Written by Li Jing
Rheumatology
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What to do about hair loss from systemic lupus erythematosus?

Systemic lupus erythematosus is a multi-system, multi-damage autoimmune disease, primarily manifesting in the skin and mucous membranes. Some individuals may also experience low-grade fever and hair loss, even severe hair loss. If treatment has already commenced and hair loss continues during the treatment process, it is necessary to consider whether the medication dosage is insufficient and to consider adjusting the medication dosage. If medication has been discontinued and severe hair loss reoccurs, the first consideration should be whether there is a recurrence of active disease, necessitating a visit to the hospital for tests including a complete blood count, erythrocyte sedimentation rate, C-reactive protein, complement levels, and autoimmune antibodies to comprehensively assess whether the disease has relapsed. If the disease has relapsed, it is necessary to reintroduce steroids, adjust medication dosages, and combine the use of hydroxychloroquine to control the disease. (Specific medications should be used under the guidance of a physician.)