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Cervical cancer
Why would someone get cervical cancer?
Why does cervical cancer occur? There are several reasons for cervical cancer: The first is infection with the human papillomavirus, also known as HPV infection, which is the fundamental cause of precancerous lesions and cervical cancer. Secondly, there are other factors; in a few cases, HPV DNA is not detected in the tumor tissue, especially among elderly patients, and it is related to early childbirth and multiple pregnancies. The third point is that cervical cancer incidence is associated with high-risk males, including those who have had penile cancer, prostate cancer, or are high-risk individuals for cervical cancer. Women who are in contact with these high-risk men are more likely to develop cervical cancer. Lastly, irregular diet and lifestyle, along with smoking and drinking, can suppress the body's immune function, potentially promoting cancer.
Causes of Cervical Cancer
The causes of cervical cancer include: The first point is infection by the human papillomavirus (HPV), particularly persistent infection with high-risk types, which is the basic cause of precancerous lesions and cervical cancer. The second point is that DNA from HPV is not detected in the tumor tissues of a minority of cases, especially among some older patients. Epidemiology shows that early childbirth and multiparity are closely related to the occurrence of cervical cancer. With an increasing number of childbirths, the risk of cervical cancer also increases. This correlation might be due to the trauma to the cervix during childbirth and changes to the endocrine and nutritional states during pregnancy.
Staging of cervical cancer
The clinical staging of cervical cancer mainly uses the FIGO system, which adopts the staging criteria of the International Federation of Gynecology and Obstetrics (FIGO). Staging should be performed before treatment, and once done it does not change after treatment. Since FIGO staging of cervical cancer primarily relies on pelvic examination, it emphasizes the necessity of this examination being conducted by two experienced gynecologic oncologists. If needed, a pelvic examination under anesthesia is performed to ensure the accuracy of the evaluation. So, how is the staging performed? It involves measuring the size of the cervical lesion, particularly the measurement of endophytic tumors, the infiltration of cervical tissue, and the status of pelvic lymph nodes, providing accurate information with the aid of radiological data, especially magnetic resonance imaging (MRI).
Cervical cancer screening
For the examination of cervical cancer, it should be based on medical history and clinical manifestations, especially for people with contact vaginal bleeding, a detailed general examination and gynecological examination should be conducted, and an examination of cervical biopsy tissue is needed for diagnosis. What specific examinations are there? There are cervical scrape cytology tests, iodine tests, colposcopy, examination of cervical and cervical canal tissue, as well as post-surgical cervical conization, and examination of postoperative specimens. Therefore, there are indeed many examinations, including some radiological assessments such as enhanced CT, PADCT, MRI, and other such tests.
How is cervical cancer treated?
The principle of treating cervical cancer is mainly through surgery and radiotherapy, supplemented by chemotherapy in a comprehensive treatment plan. Treatment should be based on clinical staging, age, overall condition, and a combination of technical level and equipment conditions to formulate an appropriate treatment plan. It emphasizes the individualization of treatment and the importance of initial treatment. Not everyone will have the same treatment plan; it should vary from person to person, with specific issues analyzed individually. Surgical options include extensive hysterectomy and extensive cervical resection. If cervical cancer is staged late, it should also be treated with radiotherapy, supplemented by chemotherapy. Nowadays, there are also targeted medications and immunotherapies to consider as part of the treatment options.
Cervical cancer treatment
For the treatment of cervical cancer, it should be based on the patient's physical condition, nutritional status, pathological staging, and pathological type to develop a comprehensive treatment plan, rather than a general, single approach. The treatment principle for cervical cancer mainly involves surgery and radiotherapy, supported by a comprehensive treatment plan that includes chemotherapy. However, the treatment plan should be based on clinical staging, age, overall health, and consider the level of technology and equipment available to formulate a suitable treatment plan. It is important to focus on individualized treatment and the method of initial treatment. Therefore, each person is different, and treatments vary from person to person and disease to disease.
Treatment of Cervical Cancer
The treatment principle of cervical cancer primarily focuses on surgical and radiotherapy, supplemented by chemotherapy and other comprehensive treatment plans. Therefore, it should be based on clinical staging and the specific condition of the patient, such as age and physical health, combined with the overall situation, as well as considering the level of technology and equipment conditions to develop a suitable treatment plan. Nowadays, emphasis is placed on personalized treatment and initial treatment. Cervical cancer treatment primarily involves surgery, including extensive hysterectomy and extensive cervical excision, where choosing the appropriate surgical method is key. Post-surgery, radiotherapy can be combined, and for those unsuitable for surgery, preoperative radiotherapy is an option. Additionally, preoperative or postoperative adjuvant chemotherapy can also be considered.
How is cervical cancer treated?
Cervical cancer is one of the malignant gynecological tumors. The treatment approach should be based on a comprehensive assessment of the disease stage, the hospital's facilities, and the patient's condition, among other factors, to develop an integrated treatment plan. The principle of cervical cancer treatment primarily involves surgery and radiotherapy, supplemented by chemotherapy as an integrated treatment plan. The treatment should consider clinical staging, age, general condition, and the overall level of technology and equipment to develop an appropriate treatment method. It is important to focus on personalized treatment and the initial treatment.
Precursors of cervical cancer
The occurrence and development of the cervix is a process from quantitative to qualitative change, evolving gradually to a sudden shift over a long period. The precursor might be the heterotypic zone of the cervix, which is a common site for abnormalities. During the formation of this heterotypic zone, cervical epithelial metaplasia is relatively active, and, compounded by infection with the human papillomavirus and further stimulated by external carcinogens, immature or proliferative squamous epithelial cells may exhibit gradual changes or atypical hyperplasia, potentially leading to sarcomatoid changes in the cervical epithelium. This might be a precursor sign.
What is cervical cancer?
Cervical erosion is one of the most common malignant gynecological tumors, belonging to a type of cervical cancer. Cervical cancer itself is a significant branch within this category, and both the incidence and mortality rates of cervical cancer are relatively high in our country. However, recent advances in medical science have led to a noticeable decline. Cervical cancer is associated with HPV (Human Papillomavirus) infection, as well as with early childbirth, multiple pregnancies, and smoking. The definitive diagnosis of cervical cancer relies on the examination of cervical and endocervical canal live tissues, colposcopic biopsy, or cervical scrape cytology. Typically, after CT, MRI, or other imaging studies, a mass may be detected. Possible symptoms of cervical cancer include vaginal bleeding and vaginal discharge.