Why would someone get cervical cancer?

Written by Gong Chun
Oncology
Updated on September 30, 2024
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Why does cervical cancer occur? There are several reasons for cervical cancer: The first is infection with the human papillomavirus, also known as HPV infection, which is the fundamental cause of precancerous lesions and cervical cancer. Secondly, there are other factors; in a few cases, HPV DNA is not detected in the tumor tissue, especially among elderly patients, and it is related to early childbirth and multiple pregnancies. The third point is that cervical cancer incidence is associated with high-risk males, including those who have had penile cancer, prostate cancer, or are high-risk individuals for cervical cancer. Women who are in contact with these high-risk men are more likely to develop cervical cancer. Lastly, irregular diet and lifestyle, along with smoking and drinking, can suppress the body's immune function, potentially promoting cancer.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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Cervical cancer is divided into several stages.

Cervical cancer is categorized into four stages based on the extent of the cancer lesion, with different stages receiving different treatments clinically. Stage I cervical cancer is the earliest stage, while stage IV cervical cancer is the latest stage, often invading organs beyond the reproductive system. Clinically, early-stage cervical cancer is primarily treated with surgical resection, followed by postoperative radiotherapy and chemotherapy to reduce the likelihood of cancer recurrence. In contrast, late-stage cervical cancer is treated primarily with radiotherapy and chemotherapy.

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Written by Gong Chun
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Cervical Cancer Staging Criteria

For the staging of cervical cancer, the staging criteria of the International Federation of Gynecology and Obstetrics (FIGO) are now adopted. Staging should be done before treatment, and since the FIGO staging of the cervix mainly relies on the examination of the pelvis, it is emphasized that the pelvic examination must be performed by two senior gynecologic oncologists. The staging primarily involves assessing the size of the cervical lesion, particularly the measurement of endophytic tumors, parametrial tissue infiltration, and the status of pelvic lymph nodes. However, these stages mainly rely on radiological examinations, primarily magnetic resonance imaging (MRI), to provide objective data for staging.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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How is cervical cancer screened?

Cervical cancer screening is a routine gynecological examination item for married women and women who are sexually active. Cervical cancer screening includes TCT (ThinPrep Cytologic Test) and HPV (Human Papillomavirus) tests. The TCT is a cytological examination of the cervix to determine if there are any cervical lesions based on cell morphology. HPV is the human papillomavirus, and its presence is a high-risk factor for cervical cancer. Therefore, cervical cancer screening consists of both TCT and HPV tests. If abnormalities are found in either test, a cervical biopsy may be necessary to confirm the presence of cervical lesions. It is best to conduct these tests between three to seven days after the end of menstruation.

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Written by Gong Chun
Oncology
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Cervical cancer treatment

For the treatment of cervical cancer, it should be based on the patient's physical condition, nutritional status, pathological staging, and pathological type to develop a comprehensive treatment plan, rather than a general, single approach. The treatment principle for cervical cancer mainly involves surgery and radiotherapy, supported by a comprehensive treatment plan that includes chemotherapy. However, the treatment plan should be based on clinical staging, age, overall health, and consider the level of technology and equipment available to formulate a suitable treatment plan. It is important to focus on individualized treatment and the method of initial treatment. Therefore, each person is different, and treatments vary from person to person and disease to disease.

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Written by Gong Chun
Oncology
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Cervical cancer screening

For the examination of cervical cancer, it should be based on medical history and clinical manifestations, especially for people with contact vaginal bleeding, a detailed general examination and gynecological examination should be conducted, and an examination of cervical biopsy tissue is needed for diagnosis. What specific examinations are there? There are cervical scrape cytology tests, iodine tests, colposcopy, examination of cervical and cervical canal tissue, as well as post-surgical cervical conization, and examination of postoperative specimens. Therefore, there are indeed many examinations, including some radiological assessments such as enhanced CT, PADCT, MRI, and other such tests.