Staging of cervical cancer

Written by Gong Chun
Oncology
Updated on September 25, 2024
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The clinical staging of cervical cancer mainly uses the FIGO system, which adopts the staging criteria of the International Federation of Gynecology and Obstetrics (FIGO). Staging should be performed before treatment, and once done it does not change after treatment. Since FIGO staging of cervical cancer primarily relies on pelvic examination, it emphasizes the necessity of this examination being conducted by two experienced gynecologic oncologists. If needed, a pelvic examination under anesthesia is performed to ensure the accuracy of the evaluation. So, how is the staging performed? It involves measuring the size of the cervical lesion, particularly the measurement of endophytic tumors, the infiltration of cervical tissue, and the status of pelvic lymph nodes, providing accurate information with the aid of radiological data, especially magnetic resonance imaging (MRI).

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Causes of cervical cancer

The causes of cervical cancer are particularly associated with human papillomavirus (HPV) infection. The primary causes that can lead to precancerous lesions and cervical cancer itself, in a minority of cases, do not detect HPV DNA, especially in older patients. Epidemiological studies show that early childbirth and multiple childbirths are highly related to the incidence of cervical cancer; as the number of childbirths increases, the risk of cervical cancer also increases. Smoking can suppress the body's immune function and may promote cancer development. Men who have had penile cancer, prostate cancer, or previous cervical cancer are at high risk; therefore, women who have contact with high-risk men are also more susceptible to cervical cancer.

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Cervical cancer leukorrhea characteristics

The characteristics of vaginal discharge in cervical cancer may include the presence of blood in the discharge. This is because cervical cancer often leads to increased vaginal discharge, which may also increase in quantity and might contain streaks of blood or bloody material. The discharge could be thin and watery or resemble rice wash water, and it might have a foul smell. In advanced stages, due to necrosis of the cancer tissue accompanied by infection, there can be a substantial amount of foul-smelling, purulent discharge resembling rice wash water. Therefore, these characteristics of the vaginal discharge are specific symptoms of cervical cancer. If such symptoms occur, it is crucial to seek medical consultation promptly to evaluate for cervical cancer.

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Causes of cervical cancer

The causes of cervical cancer are closely related to several factors. Firstly, infection with the human papillomavirus (HPV) is highly related and is the fundamental cause of precancerous lesions and cervical cancer. Secondly, although HPV DNA is not detected in the tumor tissues of a minority of cases, particularly among older patients, epidemiological surveys indicate that early childbirth and multiple childbearing are closely related to the incidence of cervical cancer. Thirdly, it has been found that the incidence of cervical cancer in women is related to contact with high-risk men, such as those with penile cancer, prostate cancer, or those whose ex-wives had cervical cancer. Fourthly, smoking has a certain relationship with the incidence of cervical cancer as it can inhibit the body's immune function. Alcohol consumption, irregular diet, and lifestyle also have certain relationships with the incidence of cervical cancer.

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Oncology
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Cervical cancer indicators

The main indicators of cervical cancer are still the examination of the cervix and cervical canal tissues. There are obvious cancerous changes, and under the microscope pathological sections can show tendencies of cell carcinogenesis, or already developed cancer. The second is the cytological examination of cervical scrapings, which detects the presence of cancer cells. The third is the iodine test, where areas that do not stain after iodine staining indicate a lack of glycogen in the epithelium, suggesting possible lesions. The fourth is colposcopy, which may reveal suspicious cancerous areas, allowing for biopsy to confirm cancer cells. The fifth includes ultrasound, CT, MRI, etc., which can detect mass occupying lesions, all of which are indicators of cervical cancer. Of course, abnormalities in tumor markers are also considered, but the main reliance is still on the indicators from pathological examinations to determine if it's cervical cancer.

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Does cervical cancer hurt?

For patients with cervical cancer, the most common clinical manifestations are bleeding during sexual intercourse and irregular vaginal bleeding. Patients who have undergone menopause may also experience irregular vaginal bleeding post-menopause, and some patients may not show any clinical signs at a very early stage. As the cancer progresses, and when it invades nearby organs and metastasizes, it may cause lower abdominal distension and pain, and even more severe pain if the metastatic organs compress nerves or directly invade areas containing nerves.