Causes of Cervical Cancer

Written by Gong Chun
Oncology
Updated on September 29, 2024
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The causes of cervical cancer include: The first point is infection by the human papillomavirus (HPV), particularly persistent infection with high-risk types, which is the basic cause of precancerous lesions and cervical cancer. The second point is that DNA from HPV is not detected in the tumor tissues of a minority of cases, especially among some older patients. Epidemiology shows that early childbirth and multiparity are closely related to the occurrence of cervical cancer. With an increasing number of childbirths, the risk of cervical cancer also increases. This correlation might be due to the trauma to the cervix during childbirth and changes to the endocrine and nutritional states during pregnancy.

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Written by Li Shun Hua
Obstetrics and Gynecology
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How to get the cervical cancer vaccine?

The cervical cancer vaccine is administered in the same way as regular vaccines, which is an injection in the deltoid muscle. However, the scheduling of the subsequent doses of the cervical cancer vaccine differs. For the bivalent cervical cancer vaccine, the second dose is administered one month after the first dose, and the third dose at six months. For the quadrivalent and nonavalent vaccines, the second dose is administered two months after the first, with the third dose given at six months.

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Written by Li Lin
Obstetrics and Gynecology
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How is cervical cancer checked?

Cervical cancer screening begins with testing for the human papillomavirus (HPV) and a cervical cytology smear test. If abnormalities are found in these tests, a colposcopy examination is needed. Under colposcopy, suspicious cancerous areas are selected for a cervical biopsy, and the cervical tissue is sent for pathological sections. Based on the results of the pathology sections, it is determined whether the condition is a precancerous lesion of the cervix or cervical cancer. If cervical cancer is present, a clinical doctor must perform a gynecological internal examination to determine the stage of the cervical cancer, and then choose a treatment plan.

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Written by Gong Chun
Oncology
48sec home-news-image

Causes of Cervical Cancer

The causes of cervical cancer include: The first point is infection by the human papillomavirus (HPV), particularly persistent infection with high-risk types, which is the basic cause of precancerous lesions and cervical cancer. The second point is that DNA from HPV is not detected in the tumor tissues of a minority of cases, especially among some older patients. Epidemiology shows that early childbirth and multiparity are closely related to the occurrence of cervical cancer. With an increasing number of childbirths, the risk of cervical cancer also increases. This correlation might be due to the trauma to the cervix during childbirth and changes to the endocrine and nutritional states during pregnancy.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
51sec home-news-image

Can cervical cancer be cured?

Cervical cancer can be treated with options including surgery, radiotherapy, and chemotherapy. For Stage 1A1 cervical cancer, a conization surgery can be chosen; for stages from 1A2 up to before 2B, a radical hysterectomy with bilateral adnexectomy and pelvic lymphadenectomy can be selected; if it is Stage 2B, where the cancer has spread to the parametrium, it is recommended to first undergo chemotherapy as preoperative neoadjuvant therapy to reduce the tumor size before proceeding with surgery; if the cancer has progressed to Stage 3A1 and beyond, radiotherapy or chemotherapy is recommended. In summary, surgical treatment can be chosen for cervical cancer before Stage 2B; if it is Stage 2B or later, involving the parametrium or the lower third of the vagina, surgery is generally not an option, and the treatment usually involves radiotherapy or chemotherapy.

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Written by Jia Rui
Obstetrics and Gynecology
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What are the symptoms of cervical cancer?

The most common symptom of cervical cancer is contact bleeding, which can manifest as bloody vaginal discharge and bleeding after sexual intercourse, as well as intermittent vaginal bleeding outside of menstrual periods. Additionally, it can present with malignant vaginal discharge, increased vaginal secretion accompanied by an unpleasant odor or foul smell, and sometimes purulent discharge. If the cervical cancer tumor spreads to adjacent organs, such as the bladder or kidneys, symptoms may include frequent urination, urinary urgency, back pain, and swelling of the lower limbs. In advanced stages, symptoms can also include anemia, fever, and weight loss.