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Amyotrophic Lateral Sclerosis
Early symptoms of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) refers to motor neuron disease, with patients initially showing mainly reduced hand strength and clumsy fine motor activities, such as difficulty and lack of agility when using a screwdriver. There may also be atrophy of small muscles, such as the interosseous muscles of the hand and the hypothenar muscles, which are commonly seen in clinical settings. Some patients may initially exhibit symptoms like unclear speech, articulation disorders, and coughing or choking while drinking, which are important to recognize. As the disease progresses, the patient's generalized weakness becomes more apparent, with noticeable fasciculations and significant muscle atrophy developing clinically.
Do people with ALS feel soreness and pain in their legs when lying down?
People with ALS often experience soreness and pain in their legs when lying down. In patients with ALS, certain neurons in the brain and spinal cord gradually degenerate and die, leading to muscle atrophy, nerve damage, muscle weakness, and stiffness, as if they are frozen. This muscle damage can lead to symptoms such as sore legs, general weakness, and fatigue. Over time, it may also cause difficulties in walking, speaking, eating, choking while drinking water, swallowing, and breathing. This can lead to systemic damage, complications like breathing difficulties, respiratory failure, and ultimately threaten life. The symptoms of leg pain and soreness in people with ALS, when lying down, can be alleviated through acupuncture, physical therapy, massage, and heat application.
Does amyotrophic lateral sclerosis skip generations in inheritance?
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, may possibly be inherited through generations. The exact cause of ALS is still not very clear, but there is a certain genetic predisposition. Patients with ALS gradually experience symptoms such as limb weakness and muscle atrophy. As the disease progresses, it will eventually lead to difficulties in speech, swallowing disorders, and breathing difficulties, resulting in the patient losing the ability to take care of themselves independently and requiring full-time care from others. Currently, ALS is an incurable disease. The treatment available to patients includes medications to nourish the nerves and systematic rehabilitation training. However, this treatment can only improve the symptoms to a certain extent and enhance the quality of life but cannot stop the progression of the disease. Eventually, the patient will be confined to bed.
Is it normal for someone with ALS to have severe swelling in their feet?
ALS patients with severe foot swelling is not normal. If an ALS patient experiences severe swelling of the feet, it is important to be cautious of the formation of blood clots in the lower limb vessels. The formation of venous blood clots can lead to poor blood circulation, easily causing blood stasis and thrombotic obstruction, leading to severe swelling of the feet. It is necessary to conduct a Doppler ultrasound of the lower limb vessels to assess their condition. Treatments may include anti-platelet aggregation, anticoagulation, promoting blood circulation to remove blood stasis, and providing nutritional support to nerves. Heat application, keeping warm, promoting lower limb blood circulation, acupuncture, physical therapy, massage, and heat application can be used as symptomatic treatments. For ALS patients with severe foot swelling, it is advisable to elevate the lower limbs during sleep, perhaps covering them with a blanket or elevating them about 45 degrees.
Is it necessary to perform a tracheotomy in the late stages of ALS?
Patients in the late stages of amyotrophic lateral sclerosis (ALS) must undergo a tracheotomy because, by this stage, they have completely lost their motor abilities, including the muscle strength needed for breathing. Consequently, they lack the strength to breathe on their own, leaving them unable to survive without a ventilator. They must rely continuously on a ventilator to breathe as they cannot do it themselves. Therefore, if a ventilator is needed over the long term, a tracheotomy is necessary. This is because other methods, such as inserting tubes through the mouth or nose into the trachea to connect to the ventilator, are quite uncomfortable. Comparatively, tracheotomy offers a bit more comfort, making it a necessary procedure for connecting to a ventilator for long-term use and achieving greater comfort.
Do people with early ALS have leg pain?
Early-stage ALS (Amyotrophic Lateral Sclerosis) patients often experience leg pain symptoms. ALS is generally caused by factors such as inflammatory reactions, genetic factors, neuronal apoptosis, infection, autoimmunity, and metal poisoning. These factors may lead to the degenerative death of nerve cells, causing muscle atrophy, muscle weakness, fasciculations, increased muscle tone, hyperactive tendon reflexes, and symptoms of muscle fatigue, muscle tension, and muscle pain. In the early stages of ALS, muscle fatigue can occur after activity due to lactic acid not being properly expelled, leading to muscle pain. Treatments such as acupuncture, physiotherapy, and massage can be administered to alleviate these symptoms.
Do people with ALS experience frequent muscle twitching?
Muscle twitching in people with ALS (Amyotrophic Lateral Sclerosis) can be very frequent. When muscles in ALS patients experience spasms, irritation, weakness, or fatigue, twitching is likely to occur. Muscle twitching in ALS patients is generally very frequent and is related to the disease. ALS, often referred to as motor neuron disease, is caused by degenerative changes in the central nervous system, such as the spinal cord and brain, leading to damage in the neuromuscular system, resulting in muscle atrophy, twitching, and tremors. It is advisable to seek medical evaluation and, once diagnosed, pursue active treatment which may include nutritional support, massage acupuncture, and functional exercise.
Does amyotrophic lateral sclerosis cause leg soreness?
Patients with amyotrophic lateral sclerosis (ALS) may experience leg pain, but leg pain is not the primary clinical manifestation of ALS. The early main symptoms of ALS include muscle atrophy and limb weakness. As the disease progresses, patients will further experience general muscle atrophy and weakness, which may manifest as difficulty in swallowing, speech problems, and respiratory difficulties. As the disease progresses, if the patient experiences extreme muscle atrophy and limb weakness, they may experience leg pain during movement, but this symptom is not specific. Therefore, when symptoms such as muscle atrophy and limb weakness occur, the possibility of ALS should be considered, and patients need to undergo timely examinations such as electromyography and muscle biopsy to confirm the diagnosis. If the patient also suffers from leg pain, other conditions such as sciatica and osteoporosis should be considered, and further examinations like bone density tests and lumbar disc magnetic resonance imaging should be conducted to clarify the diagnosis.
Can early-stage ALS be cured?
Amyotrophic lateral sclerosis, also known as motor neuron disease, is a condition that exclusively affects motor neurons without involving sensory neurons. Even if identified early, there are currently no specific medications to cure this disease; treatment can only be symptomatic and rehabilitative. Such approaches can alleviate symptoms. When symptoms are initially mild, medication can only slow down its progression but cannot cure it. The condition inevitably worsens gradually. Rehabilitative treatment can help reduce symptoms or delay the progression of the disease.
How do people with ALS eat if they can't swallow?
Patients with amyotrophic lateral sclerosis (ALS) who no longer have swallowing function can be given nasogastric feeding and intravenous hyperalimentation to maintain nutrition and electrolyte balance. For patients with respiratory difficulties or respiratory failure, oxygen supplementation can be administered. This can be combined with treatments such as acupuncture, physical therapy, massage, and heat application. It is important to prevent complications such as pulmonary infections, aspiration pneumonia, hypostatic pneumonia, lower extremity venous thrombosis, acute gastritis, gastric mucosal erosion, and gastrointestinal bleeding, which are common in later stages of ALS. With the loss of swallowing function and decreased immunity, these complications can occur more frequently and require proactive treatment to improve nutritional status.