Can early-stage ALS be cured?

Written by Shi De Quan

Neurology

Updated on September 19, 2024

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Amyotrophic lateral sclerosis, also known as motor neuron disease, is a condition that exclusively affects motor neurons without involving sensory neurons. Even if identified early, there are currently no specific medications to cure this disease; treatment can only be symptomatic and rehabilitative. Such approaches can alleviate symptoms. When symptoms are initially mild, medication can only slow down its progression but cannot cure it. The condition inevitably worsens gradually. Rehabilitative treatment can help reduce symptoms or delay the progression of the disease.

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Written by Liu Hong Mei

Neurology

52sec

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Do people with ALS feel soreness and pain in their legs when lying down?

People with ALS often experience soreness and pain in their legs when lying down. In patients with ALS, certain neurons in the brain and spinal cord gradually degenerate and die, leading to muscle atrophy, nerve damage, muscle weakness, and stiffness, as if they are frozen. This muscle damage can lead to symptoms such as sore legs, general weakness, and fatigue. Over time, it may also cause difficulties in walking, speaking, eating, choking while drinking water, swallowing, and breathing. This can lead to systemic damage, complications like breathing difficulties, respiratory failure, and ultimately threaten life. The symptoms of leg pain and soreness in people with ALS, when lying down, can be alleviated through acupuncture, physical therapy, massage, and heat application.

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Written by Liu Hong Mei

Neurology

1min 1sec

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What should people with ALS do if they cannot eat?

People with amyotrophic lateral sclerosis who are unable to eat may try liquid and semi-liquid diets, using warm liquids, eating little by little. If they cannot consume a liquid diet, they may need to resort to nasogastric feeding. A gastric tube is used for feeding, through which high-nutrition, high-protein, and high-calorie diets can be provided to sustain and extend the life of those with the condition. Avoid overeating and engage in appropriate exercise, paying attention to the functions of the respiratory and digestive systems. If there is excessive saliva, a small amount of antihistamine medication can be administered. If there is an excess of phlegm, nebulized inhalation and expectorant medications might be provided. If feeding through a gastric tube is also limited, intravenous nutritional support can be given.

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Written by Zhang Hui

Neurology

47sec

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Can amyotrophic lateral sclerosis be relieved?

Amyotrophic lateral sclerosis (ALS) refers to a motor neuron disease, and generally speaking, there are no effective alleviation measures for this disease. Currently, the specific causes and pathogenesis of this disease are not very clear. Various factors lead to the simultaneous damage of both upper and lower motor neurons in patients. Clinical manifestations include muscle weakness, muscle atrophy, and fasciculations. Additionally, patients may experience difficulties with swallowing, choking while drinking water, and speech disorders. In its most severe form, it can affect breathing, leading to respiratory failure. This disease progressively worsens, and the prognosis is generally poor with no effective relief methods available.

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Written by Liu Shi Xiang

Neurology

1min 17sec

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Does amyotrophic lateral sclerosis cause leg soreness?

Patients with amyotrophic lateral sclerosis (ALS) may experience leg pain, but leg pain is not the primary clinical manifestation of ALS. The early main symptoms of ALS include muscle atrophy and limb weakness. As the disease progresses, patients will further experience general muscle atrophy and weakness, which may manifest as difficulty in swallowing, speech problems, and respiratory difficulties. As the disease progresses, if the patient experiences extreme muscle atrophy and limb weakness, they may experience leg pain during movement, but this symptom is not specific. Therefore, when symptoms such as muscle atrophy and limb weakness occur, the possibility of ALS should be considered, and patients need to undergo timely examinations such as electromyography and muscle biopsy to confirm the diagnosis. If the patient also suffers from leg pain, other conditions such as sciatica and osteoporosis should be considered, and further examinations like bone density tests and lumbar disc magnetic resonance imaging should be conducted to clarify the diagnosis.

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Written by Liu Hong Mei

Neurology

46sec

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Do people with ALS experience frequent muscle twitching?

Muscle twitching in people with ALS (Amyotrophic Lateral Sclerosis) can be very frequent. When muscles in ALS patients experience spasms, irritation, weakness, or fatigue, twitching is likely to occur. Muscle twitching in ALS patients is generally very frequent and is related to the disease. ALS, often referred to as motor neuron disease, is caused by degenerative changes in the central nervous system, such as the spinal cord and brain, leading to damage in the neuromuscular system, resulting in muscle atrophy, twitching, and tremors. It is advisable to seek medical evaluation and, once diagnosed, pursue active treatment which may include nutritional support, massage acupuncture, and functional exercise.