Can amyotrophic lateral sclerosis be relieved?

Written by Zhang Hui
Neurology
Updated on September 04, 2024
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Amyotrophic lateral sclerosis (ALS) refers to a motor neuron disease, and generally speaking, there are no effective alleviation measures for this disease. Currently, the specific causes and pathogenesis of this disease are not very clear. Various factors lead to the simultaneous damage of both upper and lower motor neurons in patients. Clinical manifestations include muscle weakness, muscle atrophy, and fasciculations. Additionally, patients may experience difficulties with swallowing, choking while drinking water, and speech disorders. In its most severe form, it can affect breathing, leading to respiratory failure. This disease progressively worsens, and the prognosis is generally poor with no effective relief methods available.

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Written by Liu Hong Mei
Neurology
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What should people with ALS do if they cannot eat?

People with amyotrophic lateral sclerosis who are unable to eat may try liquid and semi-liquid diets, using warm liquids, eating little by little. If they cannot consume a liquid diet, they may need to resort to nasogastric feeding. A gastric tube is used for feeding, through which high-nutrition, high-protein, and high-calorie diets can be provided to sustain and extend the life of those with the condition. Avoid overeating and engage in appropriate exercise, paying attention to the functions of the respiratory and digestive systems. If there is excessive saliva, a small amount of antihistamine medication can be administered. If there is an excess of phlegm, nebulized inhalation and expectorant medications might be provided. If feeding through a gastric tube is also limited, intravenous nutritional support can be given.

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Written by Li Qiang
Intensive Care Unit
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Is it necessary to perform a tracheotomy in the late stages of ALS?

Patients in the late stages of amyotrophic lateral sclerosis (ALS) must undergo a tracheotomy because, by this stage, they have completely lost their motor abilities, including the muscle strength needed for breathing. Consequently, they lack the strength to breathe on their own, leaving them unable to survive without a ventilator. They must rely continuously on a ventilator to breathe as they cannot do it themselves. Therefore, if a ventilator is needed over the long term, a tracheotomy is necessary. This is because other methods, such as inserting tubes through the mouth or nose into the trachea to connect to the ventilator, are quite uncomfortable. Comparatively, tracheotomy offers a bit more comfort, making it a necessary procedure for connecting to a ventilator for long-term use and achieving greater comfort.

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Written by Zhang Hui
Neurology
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Can amyotrophic lateral sclerosis be relieved?

Amyotrophic lateral sclerosis (ALS) refers to a motor neuron disease, and generally speaking, there are no effective alleviation measures for this disease. Currently, the specific causes and pathogenesis of this disease are not very clear. Various factors lead to the simultaneous damage of both upper and lower motor neurons in patients. Clinical manifestations include muscle weakness, muscle atrophy, and fasciculations. Additionally, patients may experience difficulties with swallowing, choking while drinking water, and speech disorders. In its most severe form, it can affect breathing, leading to respiratory failure. This disease progressively worsens, and the prognosis is generally poor with no effective relief methods available.

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Written by Liu Hong Mei
Neurology
54sec home-news-image

Do people with early ALS have leg pain?

Early-stage ALS (Amyotrophic Lateral Sclerosis) patients often experience leg pain symptoms. ALS is generally caused by factors such as inflammatory reactions, genetic factors, neuronal apoptosis, infection, autoimmunity, and metal poisoning. These factors may lead to the degenerative death of nerve cells, causing muscle atrophy, muscle weakness, fasciculations, increased muscle tone, hyperactive tendon reflexes, and symptoms of muscle fatigue, muscle tension, and muscle pain. In the early stages of ALS, muscle fatigue can occur after activity due to lactic acid not being properly expelled, leading to muscle pain. Treatments such as acupuncture, physiotherapy, and massage can be administered to alleviate these symptoms.

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Written by Zhang Hui
Neurology
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Does amyotrophic lateral sclerosis cause numbness in the hands?

Amyotrophic lateral sclerosis (ALS) refers to a motor neuron disease. Patients with this disease generally do not experience numbness in the hands, mainly because it primarily affects the motor system and does not impact the sensory system. Thus, the vast majority of patients will not have sensory disturbances or experience clinical manifestations of numbness in the hands. The specific causes and mechanisms of this disease are still not very clear, but they may be related to genetic factors, the toxic effects of excitatory amino acids, oxidative stress, and mitochondrial dysfunction. Symptoms in patients gradually worsen, and respiratory function impairment may also occur. However, so far, there is no effective cure.