Can systemic lupus erythematosus be cured completely?

Written by Li Jing
Rheumatology
Updated on October 28, 2024
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Firstly, systemic lupus erythematosus is a chronic autoimmune disease that causes damage to multiple systems. Its occurrence is associated with factors such as genetics, environmental pollution, infections, and hormone levels. As an autoimmune disease, it cannot be completely cured. Treatment involves using medications to control symptoms, delay the onset of complications, reduce disability rates, and improve quality of life. This represents the comprehensive goals of its treatment. The first choice of treatment is corticosteroids. Once diagnosed with systemic lupus erythematosus, it is essential to conduct thorough examinations to assess the activity of the disease and the organs involved. Based on the activity of the disease and the organs affected, the dosage of treatment may vary.

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Written by Li Jing
Rheumatology
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Can systemic lupus erythematosus be cured?

Systemic lupus erythematosus is a multi-system autoimmune disease and a chronic condition with an unclear cause, making it incurable. Treatment primarily involves medication to control the progression of the disease, prevent relapse, and delay the onset of complications in other organs. The comprehensive goal of treatment is to manage these aspects. Additionally, exposure to direct sunlight should be avoided, and women should avoid oral contraceptives, as these can trigger active lupus. Furthermore, it's crucial to avoid consuming figs, bayberries, and other fruits that have been exposed to ultraviolet light over a long period, as they can also induce lupus activity.

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Written by Li Jing
Rheumatology
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Systemic Lupus Erythematosus Test Items

First, if there are symptoms such as facial erythema, butterfly rash, joint pain, hair loss, or even stillbirth or miscarriage, systemic lupus erythematosus should be suspected. For systemic lupus erythematosus, related medical tests are necessary, including complete blood count, urinalysis, erythrocyte sedimentation rate, C-reactive protein, 13 autoantibody tests, and anticardiolipin antibodies. These are the primary and most basic tests, specifically the 13 autoantibody tests. If the diagnosis is confirmed based on these tests, further assessments such as heart evaluation, chest CT need to be perfected. When necessary, 24-hour urine protein quantitation and kidney biopsy should be performed to assess the damage to the kidneys and the severity of the condition, mainly influencing the subsequent treatment plan.

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Written by Yang Ya Meng
Rheumatology
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Can people with systemic lupus erythematosus have children?

Patients with systemic lupus erythematosus can have children, but only if they are taking less than one and a half steroids and less than two hydroxychloroquine tablets. Additionally, they must be closely monitored throughout the early, middle, and late stages of pregnancy, and regularly consult with both obstetricians and rheumatologists to discuss any necessary adjustments in treatment. This is because pregnancy is a high-risk factor for triggering lupus activity, with the disease often relapsing during the first six weeks of pregnancy and the six weeks following childbirth. (Medications should be used under the guidance of a physician.)

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Written by Li Jing
Rheumatology
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Can people with systemic lupus erythematosus have children?

Firstly, systemic lupus erythematosus is an autoimmune disease of unknown etiology, and it can affect multiple organs including the heart, lungs, kidneys, and gastrointestinal tract. Once diagnosed with systemic lupus erythematosus, it is essential to complete routine urine tests, 24-hour urine protein quantification, chest CT, and other related examinations to fully assess the condition and distinguish between mild, moderate, and severe cases. Treatment plans should be formulated based on the assessment of the condition. If it is purely systemic lupus erythematosus without damage to other organs and the condition is stable with reduced maintenance doses of steroids, then pregnancy can be considered. However, during pregnancy, it is crucial to regularly monitor pulmonary arterial hypertension, pulmonary artery pressure, 24-hour urine protein quantification, and kidney function. If complications such as lupus nephritis occur, treatment decisions should be based on the condition. For instance, if there is an increase in creatinine and significant proteinuria, pregnancy is not recommended as it can exacerbate the burden on the kidneys and lead to further deterioration of kidney function.

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Written by Li Jing
Rheumatology
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Systemic lupus erythematosus is a disease.

Firstly, systemic lupus erythematosus is a chronic disease. It is an autoimmune disease that can affect multiple systems and organs and cannot be cured. It can only be controlled over the long term with medication. The goals of comprehensive treatment are to control symptoms, prevent relapses, slow the progression of the disease, and provide symptomatic treatment. Because this disease cannot be cured, it is important to avoid sun exposure, overwork, and getting chilled in daily life to prevent triggering or worsening the condition. Particularly in women, it is crucial to avoid oral contraceptives.