Firstly, systemic lupus erythematosus is a multi-system, multi-organ autoimmune disease that cannot be cured but can only be controlled with medication to slow the progression of the disease and prevent complications. Clinical manifestations are diverse, with most early symptoms typically being atypical, and sometimes not presenting any discomfort at all. Some individuals may experience acute onset, which can include high fever, progressive decline in platelets, and even progressive anemia, all characteristic of the acute phase. Other common symptoms include fever, skin erythema, and even ischemia of the extremities. Some people may experience joint pain, mainly in the finger joints and knee joints, as well as swelling of the lower limbs, chest tightness, and decreased exercise tolerance, which are more typical manifestations.