Can systemic lupus erythematosus be cured?

Written by Li Jing
Rheumatology
Updated on September 08, 2024
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Systemic lupus erythematosus is a multi-system autoimmune disease and a chronic condition with an unclear cause, making it incurable. Treatment primarily involves medication to control the progression of the disease, prevent relapse, and delay the onset of complications in other organs. The comprehensive goal of treatment is to manage these aspects. Additionally, exposure to direct sunlight should be avoided, and women should avoid oral contraceptives, as these can trigger active lupus. Furthermore, it's crucial to avoid consuming figs, bayberries, and other fruits that have been exposed to ultraviolet light over a long period, as they can also induce lupus activity.

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Written by Li Jing
Rheumatology
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What medication is used for systemic lupus erythematosus?

Systemic lupus erythematosus is a global autoimmune disease that can involve multiple systems and organs. The cause of the disease is unclear, and it cannot be completely cured; it can only be managed through medication. However, once the condition stabilizes, the medication dosage can be gradually reduced and maintained at a low dose. The preferred treatment is corticosteroids, but if there is damage to other organs, such as pulmonary interstitial fibrosis or renal damage and proteinuria, it is necessary to combine immunosuppressants. This is done to prevent recurrence of the disease and to manage complications that may arise during the reduction of steroids. Additionally, it is crucial to be cautious about sun protection, avoid oral contraceptives, and prevent exposure to cold and overexertion. (Please take medication under the guidance of a doctor.)

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Written by Li Jing
Rheumatology
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How to Treat Systemic Lupus Erythematosus?

Firstly, systemic lupus erythematosus is an autoimmune disease that commonly occurs in women of childbearing age. It is an autoimmune disease that cannot be cured but can only be managed with medications to alleviate symptoms, delay complications, and control the progression of the disease. Once diagnosed with systemic lupus erythematosus, it is necessary to score the disease activity to assess whether other organs are involved. The treatment of this disease primarily involves the use of corticosteroids, which should be calculated based on body weight. Initially, an adequate dose of corticosteroids should be administered. After stabilizing the disease for a month, the dosage should be reduced weekly. During the medication period, it is necessary to regularly monitor blood routine, liver and kidney function, complement levels, and erythrocyte sedimentation rate. (Please take medication under the guidance of a professional physician and do not self-medicate.)

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Written by Yang Ya Meng
Rheumatology
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Typical skin manifestations of systemic lupus erythematosus

The most typical skin rashes of systemic lupus erythematosus are called butterfly rash and discoid rash. The so-called butterfly rash is a rash on both sides of the nostrils, resembling the wings of a butterfly, and the so-called discoid rash is a circular, disc-shaped rash on the facial area. At the same time, patients with systemic lupus erythematosus may also experience reticular purpura or vasculitic rashes like those of end-finger vasculitis, all of which are typical manifestations of skin rashes in patients with systemic lupus erythematosus.

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Written by Yang Ya Meng
Rheumatology
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What causes systemic lupus erythematosus?

Systemic lupus erythematosus mainly has four major causes: The first is related to the environment. Long-term exposure to sunlight, or living in a humid environment, may trigger the onset of systemic lupus erythematosus. Secondly, there is a certain genetic predisposition to systemic lupus erythematosus. If the parents have systemic lupus erythematosus, the probability of their offspring developing the disease is higher. Thirdly, systemic lupus erythematosus is also related to estrogen, which is why, clinically, lupus is more commonly seen in women of childbearing age and less often in men. Systemic lupus erythematosus is also associated with some specific infections, such as bacterial or viral infections, which may trigger a lupus flare-up.

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Written by Li Jing
Rheumatology
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What to do about hair loss from systemic lupus erythematosus?

Systemic lupus erythematosus is a multi-system, multi-damage autoimmune disease, primarily manifesting in the skin and mucous membranes. Some individuals may also experience low-grade fever and hair loss, even severe hair loss. If treatment has already commenced and hair loss continues during the treatment process, it is necessary to consider whether the medication dosage is insufficient and to consider adjusting the medication dosage. If medication has been discontinued and severe hair loss reoccurs, the first consideration should be whether there is a recurrence of active disease, necessitating a visit to the hospital for tests including a complete blood count, erythrocyte sedimentation rate, C-reactive protein, complement levels, and autoimmune antibodies to comprehensively assess whether the disease has relapsed. If the disease has relapsed, it is necessary to reintroduce steroids, adjust medication dosages, and combine the use of hydroxychloroquine to control the disease. (Specific medications should be used under the guidance of a physician.)