Systemic lupus erythematosus is a chronic systemic autoimmune disease that cannot be cured. It can only be managed with medication to control the progression of the disease, reduce recurrence, delay complications, and decrease mortality and self-harm rates. These are the main treatment objectives.

Patients with systemic lupus erythematosus should avoid sun exposure and, for women, the use of oral contraceptives. It is also important to avoid overwork and staying up late. Patients are generally advised to quit smoking and drinking alcohol. Therefore, patients with systemic lupus erythematosus should not consume alcohol, especially during treatment, to avoid adverse reactions with medications.