Can ankylosing spondylitis be cured?

Written by Li Jing

Rheumatology

Updated on September 03, 2024

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Ankylosing spondylitis is an autoimmune disease, primarily characterized by the involvement of the axial joints. This disease cannot be cured, but its progression can be controlled through medication to delay joint deformity, improve quality of life, and reduce disability rates, which are also the goals of treatment. Middle-aged or young males experiencing stiffness in the neck or pain in the lower back should seek comprehensive examinations, early diagnosis, and treatment as soon as possible.

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Written by Li Jing

Rheumatology

1min 2sec

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Ankylosing Spondylitis Diagnosis Methods

Ankylosing spondylitis is primarily characterized by involvement of the elbow joints, but it can also be accompanied by extra-articular manifestations such as iritis and pain in the heel, and severe cases may present with spinal stiffness and deformity. The cause of the disease is unclear, but studies suggest it is related to genetic and environmental factors, with a significant familial aggregation. Diagnosis requires a combination of clinical symptoms, blood tests including HLA-B27, and imaging such as CT or MRI of the sacroiliac joints to confirm inflammation or damage to these joints. To diagnose ankylosing spondylitis, these three criteria must be met. The most important factor is the presence of clinical symptoms that persist for more than three months, improve with activity, and do not significantly improve with rest. This is a typical characteristic of ankylosing spondylitis.

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Written by Li Jing

Rheumatology

49sec

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Does ankylosing spondylitis hurt?

Ankylosing spondylitis primarily targets the axial joints, manifesting as a chronic autoimmune disease. The most common clinical symptoms include stiffness in the neck and pain in the lumbar and back regions, areas particularly associated with axial joint involvement, predominantly affecting the spine. Additionally, symptoms can also appear in areas outside of the joints, such as pain in the peripheral joints, heels, wrists, and shoulders. Moreover, some individuals may experience eye inflammation, including recurrent uveitis and corneal ulcers. While spinal pain, neck stiffness, and lumbar or back pain are the most commonly observed clinical manifestations, hip joint pain is also frequently noted.

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Written by Guan Jing Tao

Orthopedics

37sec

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How to exercise with ankylosing spondylitis

In the early stages of ankylosing spondylitis, when the impact on the sacral and other joints is minimal, normal activities such as swimming and jogging are acceptable. However, in the later stages of ankylosing spondylitis, as the disease progressively affects the sacral, hip, and knee joints, it becomes necessary to adjust the exercise regimen, mainly focusing on walking. It is important to avoid localized exposure to the cold and to take oral medications that nourish the joint cartilage. Daily local heat therapy for the joints or appropriate acupuncture can also help to some extent in delaying the erosion and damage of the joints by ankylosing spondylitis.

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Written by Li Jing

Rheumatology

1min 14sec

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Ankylosing Spondylitis Test Items

Ankylosing spondylitis is a systemic disease of unknown cause, primarily characterized by chronic inflammation of the axial joints. It mainly affects the sacroiliac joints and leads to bony ankylosis, predominantly occurring in males, especially young males. The disease has a significant familial genetic tendency. The main symptoms are pain or discomfort in the lower back and back, typically occurring at night, accompanied by difficulty turning over. Stiffness is evident in the morning or after sitting for a long time, but symptoms may alleviate after physical activity. In young and middle-aged males showing these symptoms, ankylosing spondylitis should be suspected first. The main diagnostic methods include blood tests for HLA-B27, and imaging such as CT or MRI of the sacroiliac joints to detect any sacroiliitis. Diagnosis primarily relies on the combination of symptoms, HLA-B27 results, and sacroiliac joint CT findings.

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Written by Na Hong Wei

Orthopedics

1min 34sec

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What is Ankylosing Spondylitis?

Ankylosing Spondylitis (AS), where "A" stands for fusion and "S" for spine, refers to the condition where the bones and joints of the spine are fused together. Ankylosing Spondylitis is defined as a chronic inflammatory disease primarily affecting the axial skeleton and major limb joints. It is characterized by fibrosis and ossification of the intervertebral discs’ annulus fibrosus and nearby connective tissues, as well as ankylosis (stiffening) of the joints. It presents as a sterile inflammation occurring in the spine. However, it is not solely limited to the spine as it also involves the axial bones and major limb joints. The pathological hallmark of the disease includes inflammation mainly at the sacroiliac joints and points of attachment to the spine, leading to joint stiffness and calcification of the spinal ligaments and joints. The disease progression begins at the sacroiliac joint, spreading upwards through the entirety of the spine, and eventually stops at the cervical vertebrae. Symptoms start with pain in the early stages, followed by restricted mobility in the intermediate phase, and ultimately leading to deformities of the abdomen and back, culminating in severe hunchback. The exact cause of Ankylosing Spondylitis remains unclear, with various theories proposed but none universally accepted. Additionally, it is categorized under rheumatologic and immunologic disorders.