Does ankylosing spondylitis spread by contagion?

Written by Li Jing
Rheumatology
Updated on September 14, 2024
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Ankylosing spondylitis is a systemic autoimmune disease of unknown cause, primarily affecting the axial joints, mainly involving the sacroiliac joints, and commonly occurring in young and middle-aged males. The symptoms of this disease are severe, progress rapidly, and there is a genetic predisposition, but it is not a contagious disease and does not have infectivity. If a patient with ankylosing spondylitis also contracts another infectious disease, it is because the other disease is infectious, not because ankylosing spondylitis is. It belongs to autoimmune diseases and cannot be cured, but can only be managed with medication to delay the onset of joint deformity.

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Written by Li Jing
Rheumatology
32sec home-news-image

Can ankylosing spondylitis be cured?

Ankylosing spondylitis is an autoimmune disease, primarily characterized by the involvement of the axial joints. This disease cannot be cured, but its progression can be controlled through medication to delay joint deformity, improve quality of life, and reduce disability rates, which are also the goals of treatment. Middle-aged or young males experiencing stiffness in the neck or pain in the lower back should seek comprehensive examinations, early diagnosis, and treatment as soon as possible.

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Written by Li Jing
Rheumatology
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How long does ankylosing spondylitis take to cause paralysis?

Ankylosing spondylitis is an autoimmune disease and a chronic condition. It primarily involves damage to the axial joints. Additionally, extrajoint manifestations can occur, such as iritis, keratitis, and corneal perforation. Currently, there is no effective cure for ankylosing spondylitis, meaning it cannot be completely cured. The treatment focuses on long-term medication management to control symptoms, delay complications, improve quality of life, and reduce disability rates. This is the main goal of treatment. Without proper treatment, deformities in the joints and spinal ankylosis can develop within a relatively short period, about seven to eight years, leading to a hunched back and significant restriction in joint mobility. Proper treatment can significantly delay joint damage. Regarding whether ankylosing spondylitis can lead to paralysis, it does not cause paralysis but does result in decreased energy and ability for activities such as turning, twisting the head, or bending, which are significantly restricted.

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Written by Na Hong Wei
Orthopedics
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What is Ankylosing Spondylitis?

Ankylosing Spondylitis (AS), where "A" stands for fusion and "S" for spine, refers to the condition where the bones and joints of the spine are fused together. Ankylosing Spondylitis is defined as a chronic inflammatory disease primarily affecting the axial skeleton and major limb joints. It is characterized by fibrosis and ossification of the intervertebral discs’ annulus fibrosus and nearby connective tissues, as well as ankylosis (stiffening) of the joints. It presents as a sterile inflammation occurring in the spine. However, it is not solely limited to the spine as it also involves the axial bones and major limb joints. The pathological hallmark of the disease includes inflammation mainly at the sacroiliac joints and points of attachment to the spine, leading to joint stiffness and calcification of the spinal ligaments and joints. The disease progression begins at the sacroiliac joint, spreading upwards through the entirety of the spine, and eventually stops at the cervical vertebrae. Symptoms start with pain in the early stages, followed by restricted mobility in the intermediate phase, and ultimately leading to deformities of the abdomen and back, culminating in severe hunchback. The exact cause of Ankylosing Spondylitis remains unclear, with various theories proposed but none universally accepted. Additionally, it is categorized under rheumatologic and immunologic disorders.

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Written by Yang Ya Meng
Rheumatology
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What tests are done for ankylosing spondylitis?

The main laboratory indicators for ankylosing spondylitis include the following: Testing for the B27 gene, formally known as HLA-B27 gene, which is hereditary and commonly found in male patients. Second, to determine if ankylosing spondylitis is in an active phase, inflammatory markers such as erythrocyte sedimentation rate and C-reactive protein can be checked. Moreover, the diagnosis of ankylosing spondylitis must involve the sacroiliac joints being affected. Therefore, a CT scan and MRI of the sacroiliac joints can be conducted to determine if there are issues with the sacroiliac joints. If the patient shows symptoms of inflammatory lower back pain, has affected sacroiliac joints, tests positive for the B27 gene, and shows elevated inflammatory markers, then a diagnosis of ankylosing spondylitis can generally be confirmed.

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Written by Li Jing
Rheumatology
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What department should I go to for ankylosing spondylitis?

Ankylosing spondylitis is an idiopathic systemic disease primarily characterized by chronic inflammation of the axial joints, mainly involving the sacroiliac joint. The typical onset age ranges from 10 to 14 years, and it is more common in males. It is not hereditary, but there is a familial predisposition. If there is a family history, and localized pain or discomfort is present, especially if there is difficulty turning over at night, stiffness after waking or after prolonged sitting or standing, which eases with activity, it is important to be alert. This condition falls under rheumatic immune diseases, therefore, it should be managed by a rheumatology immunology department, not orthopedics.