How to screen for pancreatic cancer

Written by Liu Liang
Oncology
Updated on September 11, 2024
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Pancreatic cancer is a common malignant tumor of the digestive tract. Due to its high malignancy and rapid progression, it severely affects human health. So how should pancreatic cancer patients be screened? Generally, abdominal ultrasound examination is the primary screening method. Another method is the examination of tumor markers, mainly carcinoembryonic antigen (CEA) and CA19-9. CA19-9 is a tumor marker with relatively high specificity and sensitivity for the diagnosis of pancreatic cancer. Therefore, during physical examinations, we can draw blood to check these tumor markers. If there is a significant increase in CA19-9 or CEA, further examinations of the pancreas, such as ultrasound or CT of the pancreas, should be conducted to further investigate whether there is a tumor in the pancreas.

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Written by Yan Chun
Oncology
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Early symptoms and manifestations of pancreatic cancer

Pancreatic cancer is a type of malignant tumor that has seen an increase in incidence in recent years. The early symptoms and signs of pancreatic cancer include the following: many patients experience abdominal pain, which often radiates to the shoulder and back. Additionally, some patients with early-stage pancreatic cancer may develop jaundice in the skin and mucous membranes, and some may even exhibit bleeding spots. Moreover, some patients with early-stage pancreatic cancer may show symptoms of indigestion, experiencing repeated belching, nausea, and loss of appetite. Furthermore, the symptoms of early-stage pancreatic cancer are generally not typical because the tumor is located deep within the body and is small, hence it does not invade surrounding tissues. Therefore, the clinical symptoms are neither severe nor diverse.

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Written by Yan Chun
Oncology
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What are the symptoms of pancreatic cancer?

Pancreatic cancer is a malignant tumor of the digestive system and its incidence has been increasing year by year. The symptoms of pancreatic cancer patients mainly include the following clinically: 1. Abdominal pain, which is a common manifestation in pancreatic cancer patients. It appears as intermittent pain in the early stages and as persistent severe abdominal pain in the middle and late stages. 2. Jaundice, especially common in patients with cancer of the head of the pancreas, tends to appear early. This jaundice is due to the compression of the bile duct by the tumor, often presenting as obstructive jaundice. Patients may also experience dark tea-colored urine and pale clay-colored stools. Additionally, pancreatic cancer patients may also experience symptoms like weight loss, fatigue, fever, and when the cancer metastasizes to other organs, symptoms related to the metastases may appear.

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Written by Liu Liang
Oncology
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Which test for pancreatic cancer is the most accurate?

Abdominal ultrasound and abdominal CT scans are the most commonly used imaging methods for diagnosing pancreatic cancer. Additionally, it is important to consider the patient's symptoms and blood tests for tumor markers, mainly IP antigen, CEA, and CA19-9. Confirming pancreatic cancer requires a biopsy to find cancer cells, which is the gold standard for diagnosis. Other tests can serve as screening and adjunct diagnostic tools. Confirmation requires a biopsy for pathological diagnosis or direct radical surgery followed by a postoperative pathological confirmation.

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Written by Wu Hai Wu
Gastroenterology
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How to deal with lower limb edema in advanced pancreatic cancer?

In late-stage pancreatic cancer, bilateral lower extremity edema should be considered possibly due to hypoalbuminemia, which leads to edema in both legs. It is also possible that cancer emboli in late-stage pancreatic cancer block the venous system, causing impaired venous return and resulting in bilateral lower extremity edema. To determine the specific cause, it is necessary to complete ultrasonographic examinations of the blood vessels in the lower limbs, as well as liver function tests, complete blood count, and others. After clarifying the diagnosis, appropriate treatment measures should be taken based on the different causes. For example, if the edema is caused by hypoalbuminemia, active supplementation with albumin and diuretics, among other treatments, is required. (Note: The use of medications should be carried out under the guidance of a professional doctor.)

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Written by Yan Chun
Oncology
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How is pancreatic cancer caused?

Currently, there is no consensus in clinical practice regarding the causes of pancreatic cancer, but some studies have found that certain factors contribute to its high incidence. For example, patients with diabetes have a higher incidence of pancreatic cancer compared to those without diabetes, and having chronic pancreatitis and other diseases also leads to a higher occurrence of pancreatic cancer. Additionally, factors such as genetic mutations are also associated with the development of pancreatic cancer. Some research has found that there is a certain correlation between genetic factors and the occurrence of pancreatic cancer. Once pancreatic cancer develops, it leads to a variety of symptoms in clinical settings.