What are the symptoms of pancreatic cancer?

Written by Yan Chun
Oncology
Updated on February 01, 2025
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Pancreatic cancer is a malignant tumor of the digestive system and its incidence has been increasing year by year. The symptoms of pancreatic cancer patients mainly include the following clinically: 1. Abdominal pain, which is a common manifestation in pancreatic cancer patients. It appears as intermittent pain in the early stages and as persistent severe abdominal pain in the middle and late stages. 2. Jaundice, especially common in patients with cancer of the head of the pancreas, tends to appear early. This jaundice is due to the compression of the bile duct by the tumor, often presenting as obstructive jaundice. Patients may also experience dark tea-colored urine and pale clay-colored stools. Additionally, pancreatic cancer patients may also experience symptoms like weight loss, fatigue, fever, and when the cancer metastasizes to other organs, symptoms related to the metastases may appear.

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Acute pancreatitis and pancreatic cancer are two diseases that occur in the same organ, the pancreas. However, acute pancreatitis is entirely an inflammatory change, often caused by gallstones, alcohol consumption, binge eating, and hyperlipidemia, with some cases being idiopathic. Pancreatic cancer, on the other hand, is a tumorous lesion and is a malignant tumor that generally requires surgery. Many pancreatic cancer patients are already in the advanced stages when discovered, making the surgery difficult to perform. The prognosis for patients is also completely different. After the onset of acute pancreatitis and treatment, the pancreas recovers, the inflammation subsides, and it does not affect a person's lifespan. However, if pancreatic cancer is clearly diagnosed, the lifespan oftentimes does not extend beyond a few years.

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Pancreatic cancer is a type of cancer that arises from the pancreas.

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What are the symptoms of pancreatic cancer?

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What are the symptoms of pancreatic cancer?

The clinical manifestations of pancreatic cancer mainly depend on the location of the cancer, the stage of the disease, whether there is metastasis, and the involvement of adjacent organs. The clinical characteristics include a short disease course, rapid progression, and swift deterioration. The most common symptom is upper abdominal distension and discomfort, pain, though not all patients experience tenderness; if tenderness is present, it aligns with the area of pain felt. Pain is a primary symptom of pancreatic cancer, present whether the cancer is located in the head or the body/tail of the pancreas. Jaundice is a main symptom of cancer in the head of the pancreas, and patients often exhibit more severe gastrointestinal symptoms, most commonly loss of appetite, followed by nausea and vomiting. There might also be diarrhea or constipation, even melena. Diarrhea is often steatorrhea. In the early stages of pancreatic cancer, common symptoms include weight loss and fatigue.