Early symptoms and manifestations of pancreatic cancer

Written by Yan Chun
Oncology
Updated on February 08, 2025
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Pancreatic cancer is a type of malignant tumor that has seen an increase in incidence in recent years. The early symptoms and signs of pancreatic cancer include the following: many patients experience abdominal pain, which often radiates to the shoulder and back. Additionally, some patients with early-stage pancreatic cancer may develop jaundice in the skin and mucous membranes, and some may even exhibit bleeding spots. Moreover, some patients with early-stage pancreatic cancer may show symptoms of indigestion, experiencing repeated belching, nausea, and loss of appetite. Furthermore, the symptoms of early-stage pancreatic cancer are generally not typical because the tumor is located deep within the body and is small, hence it does not invade surrounding tissues. Therefore, the clinical symptoms are neither severe nor diverse.

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Written by Yan Chun
Oncology
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What are some symptoms of early pancreatic cancer?

Patients with early-stage pancreatic cancer generally do not exhibit many symptoms, as the tumors are relatively small. Clinically, many patients may experience intermittent mild abdominal pain that does not affect their daily lives. A small number of early-stage patients may exhibit symptoms of general fatigue, mild loss of appetite, nausea, mild acid reflux, or other symptoms of indigestion. Additionally, a few patients in the early stages may experience intermittent episodes of diarrhea. Because these symptoms are not distinctive, patients rarely seek medical attention early. When symptoms like significant epigastric pain and jaundice become apparent, it often indicates that the pancreatic cancer has progressed to a more advanced stage.

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Written by Yan Chun
Oncology
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What are the signs of pancreatic cancer?

Pancreatic cancer is a type of malignant tumor of the digestive tract that is difficult to detect in its early stages. The signs of pancreatic cancer mainly include the following: First, among people with diabetes, if there is a sudden occurrence of uncontrollable blood sugar levels, unexplained general fatigue, abdominal pain, decreased appetite, or even jaundice, one should highly suspect the possibility of pancreatic cancer. Second, individuals with a family history of cancer who recently experience unexplained symptoms related to the digestive tract should also be alert to the possibility of pancreatic cancer. Third, some patients may experience unexplained rapid weight loss accompanied by significant jaundice, which should also be considered as potentially indicating pancreatic cancer.

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Written by Liu Liang
Oncology
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How to screen for pancreatic cancer

Pancreatic cancer is a common malignant tumor of the digestive tract. Due to its high malignancy and rapid progression, it severely affects human health. So how should pancreatic cancer patients be screened? Generally, abdominal ultrasound examination is the primary screening method. Another method is the examination of tumor markers, mainly carcinoembryonic antigen (CEA) and CA19-9. CA19-9 is a tumor marker with relatively high specificity and sensitivity for the diagnosis of pancreatic cancer. Therefore, during physical examinations, we can draw blood to check these tumor markers. If there is a significant increase in CA19-9 or CEA, further examinations of the pancreas, such as ultrasound or CT of the pancreas, should be conducted to further investigate whether there is a tumor in the pancreas.

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Written by Yan Chun
Oncology
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How is pancreatic cancer caused?

Currently, there is no consensus in clinical practice regarding the causes of pancreatic cancer, but some studies have found that certain factors contribute to its high incidence. For example, patients with diabetes have a higher incidence of pancreatic cancer compared to those without diabetes, and having chronic pancreatitis and other diseases also leads to a higher occurrence of pancreatic cancer. Additionally, factors such as genetic mutations are also associated with the development of pancreatic cancer. Some research has found that there is a certain correlation between genetic factors and the occurrence of pancreatic cancer. Once pancreatic cancer develops, it leads to a variety of symptoms in clinical settings.

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Written by Yan Chun
Oncology
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Early symptoms and signs of pancreatic cancer

Pancreatic cancer is a malignant tumor of the digestive system and does not have a high clinical incidence rate. Early symptoms of pancreatic cancer are not typical; some patients experience abdominal pain, primarily a persistent episodic pain that may radiate to the shoulder and back. Additionally, early-stage pancreatic head cancer patients may exhibit jaundice, often caused by obstructive jaundice due to tumor compression. Besides this, patients may also have clay-colored stools or urine the color of strong tea. Beyond these symptoms, early-stage patients exhibit no other signs. When typical clinical manifestations occur, they are generally indicative of mid to late-stage pancreatic cancer. Precursors to pancreatic cancer include persistent hidden pain in the shoulder or a stiff pain in the back. This continuous pain, often caused by the invasion of the abdominal nervous plexus, results in radiating pain.