After Mycoplasma pneumoniae infects the human body, it often causes acute bronchitis and pneumonia, with symptoms such as fever and cough. Then, is Mycoplasma pneumoniae infection stubborn, and is it easy to treat? Generally speaking, Mycoplasma pneumoniae infection is self-limiting, meaning it can resolve on its own even without medication. The natural course of the disease may last 3 to 4 weeks, and some patients may experience a longer duration. However, if treated with sensitive antibiotics, the duration of the disease may shorten to about 2 to 3 weeks. Therefore, Mycoplasma pneumoniae infection is not considered a particularly stubborn disease and is relatively easy to treat.