Is chemotherapy for gastric cancer torturous?

Written by Liu Liang
Oncology
Updated on February 14, 2025
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The first common side effect of chemotherapy drugs is gastrointestinal reactions, such as nausea, vomiting, decreased appetite, diarrhea, constipation, or bloating, and other such gastrointestinal symptoms. The second is bone marrow suppression, such as decreases in white blood cells and platelets; a decrease in white blood cells can easily lead to infections, and low platelets can lead to a tendency to bleed. There are also liver and kidney damage, numbness of hands and feet in the peripheral nervous system, and clinical symptoms such as fingernail darkening, pigmentation, or hand-foot syndrome caused by fluorouracil. The severity of chemotherapy side effects varies greatly among patients and is related to each patient's general condition, exhibiting significant individual differences. Some patients may experience severe reactions to chemotherapy, while others may have milder reactions. However, during chemotherapy, we provide corresponding symptomatic treatments such as gastric protection, antiemetics, and cardioprotection, among others, to try to minimize the side effects caused by chemotherapy.

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Written by Liu Liang
Oncology
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What are the symptoms of gastric cancer?

The symptoms of gastric cancer patients are generally common gastrointestinal symptoms such as nausea, vomiting, acid reflux, and discomfort and bloating in the upper abdomen, especially aggravated after eating. As the condition progresses, symptoms may include vomiting blood or black stools. When the cancer invades surrounding organs, clinical symptoms such as abdominal effusion, abdominal distension, and pain may occur. If the tumor is located near the pylorus and causes pyloric obstruction, symptoms of pyloric obstruction will appear, such as gastric retention, acid reflux, and vomiting of overnight food. Additionally, if the tumor bleeds, it may cause severe vomiting of blood. Therefore, different stages of the disease present different symptoms. If gastric cancer progresses to the late stage with metastasis to distant organs, clinical manifestations corresponding to the sites of metastasis will also appear.

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Written by Liu Liang
Oncology
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How is gastric cancer treated?

The treatment methods for gastric cancer include surgery, chemotherapy, and radiotherapy, as well as broad-spectrum targeted therapies against angiogenesis, such as apatinib. Immunotherapy is also an option. However, the specific treatment plan is based on a comprehensive consideration of various factors, including the stage of the cancer and the general condition of the patient. The principle is that for early-stage gastric cancer patients, if the surgeon assesses that surgery is feasible, then radical surgical treatment is primarily used. For advanced-stage patients who are in generally good condition, chemotherapy is the main treatment, combined with a consideration of whether to undergo radiotherapy. For those in very advanced stages, who may not be in good health or those who have had chemotherapy with poor results, anti-angiogenic drugs like apatinib can be chosen as a subsequent treatment.

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Written by Liu Liang
Oncology
1min 17sec home-news-image

Is chemotherapy for gastric cancer torturous?

The first common side effect of chemotherapy drugs is gastrointestinal reactions, such as nausea, vomiting, decreased appetite, diarrhea, constipation, or bloating, and other such gastrointestinal symptoms. The second is bone marrow suppression, such as decreases in white blood cells and platelets; a decrease in white blood cells can easily lead to infections, and low platelets can lead to a tendency to bleed. There are also liver and kidney damage, numbness of hands and feet in the peripheral nervous system, and clinical symptoms such as fingernail darkening, pigmentation, or hand-foot syndrome caused by fluorouracil. The severity of chemotherapy side effects varies greatly among patients and is related to each patient's general condition, exhibiting significant individual differences. Some patients may experience severe reactions to chemotherapy, while others may have milder reactions. However, during chemotherapy, we provide corresponding symptomatic treatments such as gastric protection, antiemetics, and cardioprotection, among others, to try to minimize the side effects caused by chemotherapy.

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Written by Liu Liang
Oncology
1min 4sec home-news-image

How to treat advanced gastric cancer?

The treatment for advanced gastric cancer is primarily chemotherapy, especially for patients with peritoneal or retroperitoneal lymph node metastasis, or distant organ metastasis such as to the liver or lungs. The treatment primarily involves chemotherapy, specifically choosing either multi-drug intravenous combination chemotherapy or oral monotherapy, such as oral chemotherapy with tegafur capsules, or broad-spectrum targeted therapies like apatinib that inhibit angiogenesis. The choice of treatment depends on a comprehensive consideration of the patient's overall condition. If the patient's general condition is particularly poor and the chemotherapy risk is assessed to be high, then the approach for such advanced-stage patients is primarily the best symptomatic supportive treatment to alleviate suffering as much as possible. Therefore, the treatment plan must be determined based on a comprehensive consideration of the specific situation.

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Written by Ren Zheng Xin
Gastroenterology
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Is gastric cancer contagious?

Gastric cancer is a malignant tumor occurring in the epithelial cells of the gastric mucosa. It is non-contagious. Currently, the incidence of gastric cancer is relatively high, primarily due to Helicobacter pylori infection, adverse environmental factors, and dietary irritants. Genetic factors also play a significant role, with 10% of gastric cancer patients having a family history. Those with a family history of gastric cancer have an incidence rate that is 2 to 3 times higher than the general population. Additionally, precancerous lesions can also induce gastric cancer, such as intestinal metaplasia, gastric polyps, residual gastritis, and gastric ulcers. Typical symptoms include indigestion, anemia, lack of appetite, aversion to food, and fatigue. Currently, gastroscopy combined with mucosal biopsy is the most reliable diagnostic method.