Is gastric cancer contagious?

Written by Ren Zheng Xin
Gastroenterology
Updated on January 03, 2025
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Gastric cancer is a malignant tumor occurring in the epithelial cells of the gastric mucosa. It is non-contagious. Currently, the incidence of gastric cancer is relatively high, primarily due to Helicobacter pylori infection, adverse environmental factors, and dietary irritants. Genetic factors also play a significant role, with 10% of gastric cancer patients having a family history. Those with a family history of gastric cancer have an incidence rate that is 2 to 3 times higher than the general population. Additionally, precancerous lesions can also induce gastric cancer, such as intestinal metaplasia, gastric polyps, residual gastritis, and gastric ulcers. Typical symptoms include indigestion, anemia, lack of appetite, aversion to food, and fatigue. Currently, gastroscopy combined with mucosal biopsy is the most reliable diagnostic method.

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Written by Liu Liang
Oncology
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Can stomach cancer be cured?

Whether gastric cancer can be cured depends greatly on the stage at which it is discovered. Clinically, if there is no recurrence or metastasis within five years, it is considered cured. The treatment of gastric cancer is primarily surgical. Therefore, for early-stage gastric cancer patients, if a surgeon assesses that curative surgery is feasible, it is recommended to perform a radical surgical resection. For stage I gastric cancer patients, the five-year survival rate after surgical treatment can generally reach over 90%, which is quite effective. However, for those with advanced gastric cancer, it is generally incurable. Treatments, including chemotherapy, targeted therapy, or optimal symptomatic supportive care, aim to alleviate the patient's suffering and extend their life, but generally cannot cure advanced gastric cancer.

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Written by Liu Liang
Oncology
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What is early-stage gastric cancer?

In the early stages of gastric cancer, the tumor is confined to the mucosa or submucosa, regardless of whether there is regional lymph node metastasis or not; this is still classified as early-stage gastric cancer. The treatment for early-stage gastric cancer primarily involves curative surgery, which is the first option unless the patient is of advanced age or has severe underlying diseases that prevent tolerance of surgical treatment. Excluding these cases, surgical treatment is generally the first choice. Furthermore, the outcome of surgical treatment for patients with early-stage gastric cancer is generally quite positive, with a five-year survival rate typically exceeding 80%.

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Written by Zhou Zi Hua
Oncology
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Early symptoms of gastric cancer

The symptoms of early gastric cancer are nonspecific and similar to those of chronic gastritis, gastric ulcers, gastroparesis, and other benign diseases, making it difficult to distinguish. Screening data shows that 40%-60% of patients with early gastric cancer are asymptomatic. The symptoms of early gastric cancer primarily include pain or discomfort in the upper abdomen, loss of appetite, fatigue, vomiting, hematemesis, blood in stools, melena, and difficulty swallowing. Discomfort in the upper abdomen is the most common symptom, followed by pain beneath the sternum. Generally, early gastric cancer does not present specific physical signs, though tenderness in the upper abdomen is relatively common, and some patients may exhibit signs of anemia.

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Written by Liu Liang
Oncology
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Does early-stage stomach cancer hurt?

Symptoms of early-stage gastric cancer are generally not very obvious. Some patients may experience subtle symptoms resembling those of gastritis or gastrointestinal ulcers, including non-specific gastrointestinal symptoms such as discomfort and bloating in the upper abdomen, acid reflux, nausea, vomiting, and decreased appetite. In terms of pain, early-stage gastric cancer patients might only experience a sensation of bloating or mild tenderness in the upper abdomen. Severe pain is usually associated with late-stage gastric cancer, occurring when there is extensive abdominal metastasis or tumor progression, and the tumor is large enough to cause significant pain, requiring analgesics for treatment.

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Written by Liu Liang
Oncology
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How is stomach cancer treated?

The treatment for gastric cancer now includes surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy, among others. The specific treatment plan is formulated based on various factors such as the staging of the cancer, the patient's overall condition, and the presence of any underlying diseases, which are all taken into consideration before deciding on a treatment plan. For patients in the early stages who are generally in good condition, surgical resection can be evaluated and is primarily curative. Post-operative treatment decisions, such as whether to pursue adjuvant radiotherapy or chemotherapy, depend on the pathology results and the presence of high-risk factors for recurrence. For patients in advanced stages who are found to have distant metastases upon diagnosis, treatment is primarily chemotherapy. Additionally, there are broad-spectrum targeted therapies against angiogenesis, such as apatinib, which are suitable for patients with advanced gastric cancer or those who do not respond well to chemotherapy, serving as a secondary or tertiary line of treatment. These are some of the treatment methods for gastric cancer. It is crucial that the use of any medication is conducted under the guidance of a doctor.