Does early-stage stomach cancer hurt?

Written by Liu Liang
Oncology
Updated on September 10, 2024
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Symptoms of early-stage gastric cancer are generally not very obvious. Some patients may experience subtle symptoms resembling those of gastritis or gastrointestinal ulcers, including non-specific gastrointestinal symptoms such as discomfort and bloating in the upper abdomen, acid reflux, nausea, vomiting, and decreased appetite. In terms of pain, early-stage gastric cancer patients might only experience a sensation of bloating or mild tenderness in the upper abdomen. Severe pain is usually associated with late-stage gastric cancer, occurring when there is extensive abdominal metastasis or tumor progression, and the tumor is large enough to cause significant pain, requiring analgesics for treatment.

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Written by Liu Liang
Oncology
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Late-stage symptoms of gastric cancer

The common late-stage symptoms of gastric cancer patients include nausea, vomiting, and even a complete inability to eat. There are also symptoms related to the digestive tract such as pain in the upper abdomen and acid reflux, as well as upper gastrointestinal bleeding, such as vomiting blood and melena which are signs of lower gastrointestinal bleeding. Late-stage gastric cancer patients may also experience organ metastasis, leading to corresponding symptoms. For example, metastasis of gastric cancer to the liver can cause abdominal pain and ascites due to hepatic metastatic tumors. Clinical manifestations caused by such metastatic tumors also include metastasis to retroperitoneal lymph nodes in the abdominal cavity, a common site of spread for gastric cancer. Patients may even show symptoms of intestinal obstruction, such as abdominal pain, bloating, nausea, vomiting, inability to pass stool, or even absence of flatus, which are indicators of intestinal obstruction. Consequently, patients might experience weight loss and deteriorate into a cachectic state, marked by poor nutrition and significant weight loss, which are characteristic symptoms of late-stage patients.

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Oncology
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What is early-stage gastric cancer?

In the early stages of gastric cancer, the tumor is confined to the mucosa or submucosa, regardless of whether there is regional lymph node metastasis or not; this is still classified as early-stage gastric cancer. The treatment for early-stage gastric cancer primarily involves curative surgery, which is the first option unless the patient is of advanced age or has severe underlying diseases that prevent tolerance of surgical treatment. Excluding these cases, surgical treatment is generally the first choice. Furthermore, the outcome of surgical treatment for patients with early-stage gastric cancer is generally quite positive, with a five-year survival rate typically exceeding 80%.

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Written by Zhou Zi Hua
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What are the symptoms of stomach cancer?

Gastric cancer can cause pain in the upper abdomen. If the condition gradually worsens, it can manifest as persistent pain, postprandial fullness and vomiting, belching, and lack of appetite; upper gastrointestinal bleeding, manifesting as vomiting blood, blood in the stool, and black stools; there can also be difficulty swallowing, weight loss and anemia. If bone metastasis occurs, it can manifest as bone pain and pain in the lower back. If a large amount of ascites appears, it can lead to abdominal distension, with shifting dullness detectable on percussion. If liver metastasis occurs, it can manifest as jaundice, and enlargement of the supraclavicular lymph nodes can also occur.

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Oncology
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How is gastric cancer treated?

The treatment methods for gastric cancer include surgery, chemotherapy, and radiotherapy, as well as broad-spectrum targeted therapies against angiogenesis, such as apatinib. Immunotherapy is also an option. However, the specific treatment plan is based on a comprehensive consideration of various factors, including the stage of the cancer and the general condition of the patient. The principle is that for early-stage gastric cancer patients, if the surgeon assesses that surgery is feasible, then radical surgical treatment is primarily used. For advanced-stage patients who are in generally good condition, chemotherapy is the main treatment, combined with a consideration of whether to undergo radiotherapy. For those in very advanced stages, who may not be in good health or those who have had chemotherapy with poor results, anti-angiogenic drugs like apatinib can be chosen as a subsequent treatment.

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Can stomach cancer be cured? Can stomach cancer be cured?

Early-stage gastric cancer patients can undergo curative surgery, and then decide whether postoperative adjuvant radiochemotherapy is needed based on the specific pathological type and the presence of high-risk recurrence factors. Through these treatments, a cure can be achieved. Generally, if there is no recurrence or metastasis within five years, it is considered cured. For example, patients in stage IA, even without adjuvant chemotherapy, have a relatively high five-year survival rate, generally above 90% after curative surgery. However, if it is found to be advanced-stage, such as initial detection showing distant metastases to the liver, lungs, etc., these patients are primarily treated with systemic chemotherapy or symptomatic palliative care. In such cases, a cure is not achievable. Therefore, whether a cure is possible depends on the stage of gastric cancer and factors such as the patient's basic physical condition.