Is the ankle pain due to gout or rheumatoid arthritis?

Written by Wang Cheng Lin
Orthopedics
Updated on September 16, 2024
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In clinical practice, the first reason for ankle pain is rheumatic or rheumatoid arthritis, which mainly involves the synovium of the joint in the early stages, causing synovial hyperplasia and effusion leading to pain. The second cause is gout, which is due to dietary habits, such as frequent consumption of greasy or seafood-based foods, and a preference for beer, leading to increased uric acid levels and gout. The third cause is osteoarthritis in middle-aged and elderly people, which leads to degeneration of joint cartilage and pain. The fourth cause is sprains, which can lead to damage to cartilage and ligaments within the joint, causing pain. To determine whether ankle pain is caused by gout or rheumatic arthritis, one can simply visit a hospital for a checkup, such as a uric acid test to see if there is a significant increase in gout uric acid levels. If the uric acid level is significantly elevated, it is likely caused by gout. Additionally, one can check for a rheumatism panel to see if the anti-O test is positive; if it is, it may suggest that rheumatic factors are causing the pain.

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Written by Guan Yu Hua
Orthopedic Surgery
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Difference between arthritis and rheumatoid arthritis

Arthritis is typically osteoarthritis, a chronic inflammation characterized primarily by degenerative changes in joint cartilage, followed by bone proliferation, making it a chronic disease. Early pathological changes include alterations in joint cartilage, such as subchondral bone extrusion, followed by changes in the muscles surrounding the periosteum and joint capsule. Early radiographic examinations can provide a definitive diagnosis. Its symptoms primarily manifest as pain. For rheumatoid arthritis, it generally presents as morning stiffness and joint swelling and pain more severe than in the surrounding area, which can essentially confirm a diagnosis. It usually affects large joints such as the knee, shoulder, or wrist joints, typically presenting as migratory pain. A definitive diagnosis can usually be made by testing for rheumatoid factor, with an anti-O level exceeding 500 units. Additionally, there may be a slight increase in white blood cells, accelerated erythrocyte sedimentation rate, and elevated C-reactive protein. Examination of the synovial fluid shows increased white blood cells and neutrophils. In such cases, using anti-rheumatic drugs might suffice, but it’s also crucial to ensure rest and local heat application. These two types of arthritis fundamentally differ.

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Written by Liu Li Ning
Rheumatology
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Rheumatoid arthritis hurts more at night or during the day?

The pain of rheumatoid arthritis is irregular. It can hurt at night or during the day, and it varies from person to person. The onset of rheumatoid arthritis is somewhat related to streptococcal infection. Clinically, it mainly presents as migratory swelling and pain in the large joints of the limbs, generally without leaving joint deformities. The onset of rheumatoid arthritis is related to streptococcal infection, so it requires treatment with penicillin antibiotics. During the acute phase, it is also recommended to use non-steroidal anti-inflammatory drugs to alleviate symptoms. Commonly used drugs include sustained-release capsules of diclofenac sodium, meloxicam, or etoricoxib.

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Written by Yang Ya Meng
Rheumatology
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Will rheumatoid arthritis RF be high?

Patients with rheumatic arthritis generally do not have elevated rheumatoid factor levels, but there may also be a slight, minor increase. Typically, high titers of positive rheumatoid factors are not present. If a patient with rheumatic arthritis has a significant increase in rheumatoid factor, that is, more than three times the normal value, we need to reconsider the diagnosis of rheumatic arthritis. At this point, further tests are required to refine the diagnosis, including ASO (anti-streptolysin O), ESR (erythrocyte sedimentation rate), CRP (C-reactive protein), anti-CCP antibody, and anti-AK antibody, to better determine whether the condition is rheumatic arthritis or rheumatoid arthritis.

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Written by Lv Yao
Orthopedics
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The difference between osteoarthritis and rheumatoid arthritis.

Osteoarthritis refers to the damage of joint cartilage due to degeneration in old age, which can cause symptoms such as joint pain, limited mobility, and deformity. Rheumatoid arthritis, on the other hand, involves the destruction of joint cartilage solely due to rheumatic diseases, particularly accompanied by abnormal proliferation of the synovium, causing pain and local heating, and resulting in limited joint mobility. Rheumatic diseases feature migrating joint pain, which worsens when exposed to cold. Additionally, diagnostic indicators such as positive rheumatoid factor will show increased levels, thus making it relatively easy to distinguish between osteoarthritis and rheumatoid arthritis.

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Written by Yang Ya Meng
Rheumatology
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How is rheumatoid arthritis treated?

The treatment methods for rheumatoid arthritis mainly fall into three categories: The first category is anti-inflammatory analgesics, which include non-steroidal analgesic drugs such as slow-release diclofenac sodium. For patients with especially high inflammatory indicators, low-dose corticosteroids may also be considered. The second category of drugs includes slow-acting drugs commonly used in the treatment of rheumatoid arthritis, such as methotrexate and leflunomide, which are immunosuppressants. If the patient does not respond well to non-steroidal analgesic drugs or immunosuppressants, biological agents can be considered as a treatment option. Common biological agents include tumor necrosis factor antagonists. (Specific medications should be taken under the guidance of a physician.)