Rheumatoid arthritis hurts more at night or during the day?

Written by Liu Li Ning

Rheumatology

Updated on January 05, 2025

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The pain of rheumatoid arthritis is irregular. It can hurt at night or during the day, and it varies from person to person. The onset of rheumatoid arthritis is somewhat related to streptococcal infection. Clinically, it mainly presents as migratory swelling and pain in the large joints of the limbs, generally without leaving joint deformities. The onset of rheumatoid arthritis is related to streptococcal infection, so it requires treatment with penicillin antibiotics. During the acute phase, it is also recommended to use non-steroidal anti-inflammatory drugs to alleviate symptoms. Commonly used drugs include sustained-release capsules of diclofenac sodium, meloxicam, or etoricoxib.

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Written by Li Jing

Rheumatology

51sec

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Treatment of Acute Flare-ups of Rheumatoid Arthritis

During the acute phase of rheumatoid arthritis, typical treatment includes absolute bed rest and avoiding intense physical activities, followed by a diet rich in fresh fruits and vegetables containing vitamins. Medication-wise, sodium diclofenac or meloxicam are used, which are non-steroidal drugs that relieve joint pain. If these drugs are not effective, steroids such as methylprednisolone are administered, initially at doses of 20 mg or 40 mg, until the pain eases, then gradually reducing the steroid dosage. During steroid treatment, it's also important to prevent side effects, namely, by supplementing with calcium and incorporating drugs that protect the stomach lining. (The above medications should be used under medical supervision.)

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Written by Guan Yu Hua

Orthopedic Surgery

1min 28sec

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Difference between arthritis and rheumatoid arthritis

Arthritis is typically osteoarthritis, a chronic inflammation characterized primarily by degenerative changes in joint cartilage, followed by bone proliferation, making it a chronic disease. Early pathological changes include alterations in joint cartilage, such as subchondral bone extrusion, followed by changes in the muscles surrounding the periosteum and joint capsule. Early radiographic examinations can provide a definitive diagnosis. Its symptoms primarily manifest as pain. For rheumatoid arthritis, it generally presents as morning stiffness and joint swelling and pain more severe than in the surrounding area, which can essentially confirm a diagnosis. It usually affects large joints such as the knee, shoulder, or wrist joints, typically presenting as migratory pain. A definitive diagnosis can usually be made by testing for rheumatoid factor, with an anti-O level exceeding 500 units. Additionally, there may be a slight increase in white blood cells, accelerated erythrocyte sedimentation rate, and elevated C-reactive protein. Examination of the synovial fluid shows increased white blood cells and neutrophils. In such cases, using anti-rheumatic drugs might suffice, but it’s also crucial to ensure rest and local heat application. These two types of arthritis fundamentally differ.

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Written by Yang Ya Meng

Rheumatology

1min 1sec

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How long does it take to cure rheumatoid arthritis?

The symptoms of rheumatic arthritis, such as joint swelling and pain, generally improve on their own within about two weeks, with the longest duration not exceeding one month. However, since rheumatic arthritis is triggered by a Streptococcus infection, if the Streptococcus infection is not actively controlled, it is easy for the arthritis to relapse after the joint pain has improved. Therefore, for patients with rheumatic arthritis, it is essential to treat the Streptococcus infection early. Treatment with second-generation cephalosporin antibiotics for 10-14 days is recommended, followed by regular long-acting benzathine penicillin treatment at outpatient clinics to achieve a complete cure of rheumatic arthritis. (Specific medications should be used under the guidance of a doctor.)

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Written by Lv Yao

Orthopedics

45sec

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The difference between osteoarthritis and rheumatoid arthritis.

Osteoarthritis refers to the damage of joint cartilage due to degeneration in old age, which can cause symptoms such as joint pain, limited mobility, and deformity. Rheumatoid arthritis, on the other hand, involves the destruction of joint cartilage solely due to rheumatic diseases, particularly accompanied by abnormal proliferation of the synovium, causing pain and local heating, and resulting in limited joint mobility. Rheumatic diseases feature migrating joint pain, which worsens when exposed to cold. Additionally, diagnostic indicators such as positive rheumatoid factor will show increased levels, thus making it relatively easy to distinguish between osteoarthritis and rheumatoid arthritis.

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Written by Liu Li Ning

Rheumatology

1min 8sec

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Rheumatoid arthritis is caused by what?

Rheumatic arthritis is a type of infectious arthritis caused by streptococcal infection and is one of the clinical manifestations of rheumatism. It primarily presents as migratory pain in large joints, most commonly affecting the large joints of the lower limbs, such as the knees, ankles, wrists, etc. Since rheumatic arthritis is related to streptococcal infection, treatment mainly involves the use of penicillin drugs, commonly long-acting penicillin, which requires strict adherence to the treatment course to completely cure the streptococcal infection. During the acute phase, joint pain often occurs, hence the common use of non-steroidal anti-inflammatory drugs, such as diclofenac sodium and etoricoxib, to alleviate symptoms of pain. During acute episodes, bed rest is necessary, with attention to joint immobilization. During the remission period, getting out of bed and exercising is encouraged to restore joint function and flexibility. (Please use medications under the guidance of a professional physician; do not self-medicate.)