Difference between arthritis and rheumatoid arthritis

Written by Guan Yu Hua
Orthopedic Surgery
Updated on December 05, 2024
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Arthritis is typically osteoarthritis, a chronic inflammation characterized primarily by degenerative changes in joint cartilage, followed by bone proliferation, making it a chronic disease. Early pathological changes include alterations in joint cartilage, such as subchondral bone extrusion, followed by changes in the muscles surrounding the periosteum and joint capsule. Early radiographic examinations can provide a definitive diagnosis. Its symptoms primarily manifest as pain. For rheumatoid arthritis, it generally presents as morning stiffness and joint swelling and pain more severe than in the surrounding area, which can essentially confirm a diagnosis. It usually affects large joints such as the knee, shoulder, or wrist joints, typically presenting as migratory pain. A definitive diagnosis can usually be made by testing for rheumatoid factor, with an anti-O level exceeding 500 units. Additionally, there may be a slight increase in white blood cells, accelerated erythrocyte sedimentation rate, and elevated C-reactive protein. Examination of the synovial fluid shows increased white blood cells and neutrophils. In such cases, using anti-rheumatic drugs might suffice, but it’s also crucial to ensure rest and local heat application. These two types of arthritis fundamentally differ.

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Written by Yang Ya Meng
Rheumatology
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What medicine should be taken for rheumatoid arthritis?

Medications for rheumatoid arthritis firstly include some anti-inflammatory and analgesic drugs, commonly used are non-steroidal pain relievers such as Diclofenac Sodium Sustained Release Tablets and the like. The second, and most important, are what we call slow-acting drugs, which are often immunosuppressants, commonly used ones include Methotrexate, Leflunomide Tablets and the like. If the patient does not respond well to conventional oral medications, we can also use biologic treatments. Before using biologics, we need to strictly rule out hepatitis, tuberculosis, tumors, and some common infections. Commonly used biologics include tumor necrosis factor antagonists and similar drugs. (The use of medications should be conducted under the guidance of a professional doctor.)

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Written by Guan Yu Hua
Orthopedic Surgery
1min 28sec home-news-image

Difference between arthritis and rheumatoid arthritis

Arthritis is typically osteoarthritis, a chronic inflammation characterized primarily by degenerative changes in joint cartilage, followed by bone proliferation, making it a chronic disease. Early pathological changes include alterations in joint cartilage, such as subchondral bone extrusion, followed by changes in the muscles surrounding the periosteum and joint capsule. Early radiographic examinations can provide a definitive diagnosis. Its symptoms primarily manifest as pain. For rheumatoid arthritis, it generally presents as morning stiffness and joint swelling and pain more severe than in the surrounding area, which can essentially confirm a diagnosis. It usually affects large joints such as the knee, shoulder, or wrist joints, typically presenting as migratory pain. A definitive diagnosis can usually be made by testing for rheumatoid factor, with an anti-O level exceeding 500 units. Additionally, there may be a slight increase in white blood cells, accelerated erythrocyte sedimentation rate, and elevated C-reactive protein. Examination of the synovial fluid shows increased white blood cells and neutrophils. In such cases, using anti-rheumatic drugs might suffice, but it’s also crucial to ensure rest and local heat application. These two types of arthritis fundamentally differ.

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Written by Liu Li Ning
Rheumatology
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Do you need to take X-rays for rheumatoid arthritis?

Rheumatoid arthritis requires imaging, especially of the affected joints. It is typically necessary to do this routinely. The main purpose is to check for any bone damage, primarily to differentiate it from rheumatoid arthritis. Because rheumatoid arthritis generally does not leave joint deformities, while rheumatoid arthritis, if not treated properly, can lead to bone destruction and in severe cases, joint fusion. In addition to imaging, rheumatoid arthritis also requires complete blood count, erythrocyte sedimentation rate, C-reactive protein, anti-streptolysin O, and echocardiography among other tests to comprehensively assess the condition and determine the treatment plan.

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Written by Li Jing
Rheumatology
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What is the best medicine to take for rheumatoid arthritis?

Rheumatoid arthritis is a clinical manifestation of rheumatic fever, which is a delayed sequelae that occurs after infection with streptococci. The most common symptoms include fever, arthritis, rheumatic heart disease, subcutaneous nodules, or marginal erythema. It mainly occurs in adolescents and is most commonly triggered by cold weather and damp environments. In cases showing joint symptoms, the first choice of medication is nonsteroidal anti-inflammatory drugs (NSAIDs). Additionally, it is crucial to actively treat the primary disease, which means eliminating the causative factor by eradicating the streptococcal infection. Eradication of the streptococcal infection involves the use of long-acting penicillin, and it is necessary to complete the treatment course of two weeks. Moreover, appropriate rest during the acute phase and avoiding exertion is needed. (Please use medication under the guidance of a professional physician and do not self-medicate.)

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Written by Yang Ya Meng
Rheumatology
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How is rheumatoid arthritis treated?

Rheumatoid arthritis, also commonly referred to as internal rheumatoid arthritis, primarily has three major categories of treatment. The first category is anti-inflammatory and pain relief. The medications for anti-inflammatory pain relief include two types: the first type is non-steroidal pain relievers; for patients with very severe pain, a low dose of corticosteroids can be considered. The second category, which is also the most important treatment, involves the use of immunosuppressants. These immunosuppressants include drugs such as methotrexate and leflunomide. If the patient does not respond well to anti-inflammatory pain relief and immunosuppressants, treatment with biologics can also be considered.