The difference between osteoarthritis and rheumatoid arthritis.

Written by Lv Yao
Orthopedics
Updated on September 16, 2024
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Osteoarthritis refers to the damage of joint cartilage due to degeneration in old age, which can cause symptoms such as joint pain, limited mobility, and deformity. Rheumatoid arthritis, on the other hand, involves the destruction of joint cartilage solely due to rheumatic diseases, particularly accompanied by abnormal proliferation of the synovium, causing pain and local heating, and resulting in limited joint mobility. Rheumatic diseases feature migrating joint pain, which worsens when exposed to cold. Additionally, diagnostic indicators such as positive rheumatoid factor will show increased levels, thus making it relatively easy to distinguish between osteoarthritis and rheumatoid arthritis.

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Written by Yang Ya Meng
Rheumatology
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Rheumatoid arthritis diagnostic tests

The diagnostic tests for rheumatoid arthritis include blood tests and X-ray examinations. Blood tests include a complete blood count, inflammatory markers, erythrocyte sedimentation rate, C-reactive protein, and screening for various antibodies such as rheumatoid factor, anti-O, anti-CCP antibodies, and anti-AKA antibodies. Additionally, if there is significant pain in the hand joints, an X-ray of the hand joints can be taken. The X-ray can show whether there is any destruction of bone, osteoporosis, or other manifestations of rheumatoid disease. Based on these tests, it is generally possible to diagnose the specific type of rheumatoid disease.

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Written by Li Jing
Rheumatology
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Symptoms and treatment methods of rheumatoid arthritis

Rheumatic arthritis is mostly related to streptococcal infections. Additionally, respiratory viruses and mycoplasma infections can also cause joint pain. Once joint pain occurs, especially if it is asymmetrical, one should consider these infection-related factors, thus necessitating comprehensive tests including anti-streptolysin O, erythrocyte sedimentation rate, and respiratory virus tests. Whether to treat rheumatic arthritis depends on symptoms like fever and joint pain. Should there be fever and joint pain, proper medication is required, primarily the use of anti-inflammatory drugs, specifically non-steroidal ones. Treatment should be combined with long-term administration of penicillin to ensure a full course of therapy. If joint pain occurs, immobilization is essential, meaning bed rest is necessary until the joint pain eases. During this period, a light diet and adequate water intake are also recommended. (Please follow the guidance of a professional physician for medication use.)

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Written by Yang Ya Meng
Rheumatology
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Can rheumatoid arthritis be cured?

Rheumatoid arthritis is difficult to completely cure without medication, as it is a chronic inflammatory disease of the immune system that requires lifelong medication. The main treatment plans include the following three categories: The first category is anti-inflammatory and analgesic, which includes non-steroidal analgesics and low-dose corticosteroids. The second category, which is also the most important treatment, involves the use of immunosuppressants. Commonly used immunosuppressants include methotrexate and leflunomide. If the patient does not respond well to anti-inflammatory analgesics and immunosuppressants, treatment with biological agents may also be considered. (Medications should be used under the guidance of a doctor.)

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Written by Yang Ya Meng
Rheumatology
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Will rheumatoid arthritis RF be high?

Patients with rheumatic arthritis generally do not have elevated rheumatoid factor levels, but there may also be a slight, minor increase. Typically, high titers of positive rheumatoid factors are not present. If a patient with rheumatic arthritis has a significant increase in rheumatoid factor, that is, more than three times the normal value, we need to reconsider the diagnosis of rheumatic arthritis. At this point, further tests are required to refine the diagnosis, including ASO (anti-streptolysin O), ESR (erythrocyte sedimentation rate), CRP (C-reactive protein), anti-CCP antibody, and anti-AK antibody, to better determine whether the condition is rheumatic arthritis or rheumatoid arthritis.

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Written by Liu Li Ning
Rheumatology
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Does rheumatoid arthritis have anything to do with drinking alcohol?

Rheumatoid arthritis is not causally related to alcohol consumption. There is a certain correlation between rheumatoid arthritis and Group A beta-hemolytic streptococcus infection. Clinically, it is mainly manifested as joint pain or arthritis, primarily affecting major joints. Symptoms can include redness, swelling, heat, and pain in the joints, which are migratory, and generally do not leave joint deformities. During the acute phase of rheumatoid arthritis, it is important to immobilize the joints. Non-steroidal anti-inflammatory drugs, such as etoricoxib or diclofenac sodium sustained-release capsules, can be used to relieve symptoms. If accompanied by myocarditis, glucocorticoids can also be applied in combination therapy.