Upper gastrointestinal bleeding results in the vomiting of coffee-colored blood because the combination of fresh blood with stomach acid forms a coffee-colored liquid. If the bleeding volume exceeds 200mL in a short period, coffee-colored vomit may occur. It is necessary to seek prompt medical attention at a regular hospital’s gastroenterology or emergency department. Adequate diagnosis with an electronic gastroscopy is essential to identify the source and location of the bleeding, and active endoscopic treatment should be undertaken. Additionally, it is crucial to actively replenish fluids, correct the loss of body water, and restore blood volume. Treatment should also include the use of proton pump inhibitors and gastric mucosal protectants.