Upper gastrointestinal massive bleeding is generally a medical emergency with rapid changes that can even be life-threatening. Immediate anti-shock treatment and rapid blood volume replenishment are necessary. When massive gastrointestinal bleeding occurs, the patient should be kept in a recumbent position for rest, ensuring that the airway remains clear to avoid choking during vomiting, and fasting should be maintained during the bleeding period. In clinical practice, medical treatment mainly includes the following points: firstly, actively preparing blood transfusions to replenish blood volume. Secondly, vasopressin can be used for pharmacological hemostasis. Additionally, treatments with somatostatin and octreotide are also options. Hemostasis can also be achieved through endoscopic treatment. If conservative medical treatment is ineffective, surgical treatment may be considered. (Please use medications under the guidance of a doctor.)