ovarian cancer specific drug

Written by Liu Liang
Oncology
Updated on September 15, 2024
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Ovarian cancer does not have any specific cure-all treatment. Most ovarian cancers are epithelial ovarian cancers, and there is also ovarian cancer resulting from malignant germ cells, which is a rarer pathology type. For epithelial ovarian cancer, treatment methods include surgery, radiation therapy, chemotherapy, and some targeted therapies, mainly using Bevacizumab, which is a monoclonal antibody that inhibits angiogenesis, and is usually used in combination with chemotherapy drugs. For patients with advanced ovarian cancer, those who are resistant to chemotherapy, or those in poor general health unable to endure chemotherapy, palliative treatments like hormone treatment using progestogens are an option, along with immune therapy being available nowadays. Surgery is primarily for early-stage ovarian cancer patients, where curative surgical resection is possible, or for debulking surgery in patients with advanced ovarian cancer. Chemotherapy is frequently used as it is relatively effective for epithelial ovarian cancer, a type of cancer that is somewhat sensitive to such treatments. The drugs used mainly include taxane combined with platinum-based chemotherapy. For intravenous administration or intraperitoneal delivery—for the latter, mainly for ovarian cancers complicated by extensive ascites—, positioning an abdominal drainage tube and then infusing platinum-based chemotherapy drugs into the abdominal cavity are utilized.

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Written by Liu Liang
Oncology
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Symptoms of ovarian cancer

Ovarian cancer patients, especially those in the early stages, typically have inconspicuous symptoms, possibly without any noticeable discomfort. The disease is often discovered during gynecological examinations through the detection of abdominal masses. In advanced-stage patients, as the abdominal mass progressively enlarges, symptoms may include abdominal pain, lower abdominal bloating, and pelvic pressure symptoms due to compression of nearby organs. There may be partial intestinal obstruction, presenting as nausea, vomiting, abdominal pain, and inability to pass stool or gas. Another symptom is ascites, characterized by progressive enlargement and bloating of the abdomen. Ascites is a common clinical manifestation in ovarian cancer patients, and a significant portion of patients are diagnosed with ovarian cancer after presenting with ascites as the initial symptom.

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Written by Liu Liang
Oncology
1min 50sec home-news-image

ovarian cancer specific drug

Ovarian cancer does not have any specific cure-all treatment. Most ovarian cancers are epithelial ovarian cancers, and there is also ovarian cancer resulting from malignant germ cells, which is a rarer pathology type. For epithelial ovarian cancer, treatment methods include surgery, radiation therapy, chemotherapy, and some targeted therapies, mainly using Bevacizumab, which is a monoclonal antibody that inhibits angiogenesis, and is usually used in combination with chemotherapy drugs. For patients with advanced ovarian cancer, those who are resistant to chemotherapy, or those in poor general health unable to endure chemotherapy, palliative treatments like hormone treatment using progestogens are an option, along with immune therapy being available nowadays. Surgery is primarily for early-stage ovarian cancer patients, where curative surgical resection is possible, or for debulking surgery in patients with advanced ovarian cancer. Chemotherapy is frequently used as it is relatively effective for epithelial ovarian cancer, a type of cancer that is somewhat sensitive to such treatments. The drugs used mainly include taxane combined with platinum-based chemotherapy. For intravenous administration or intraperitoneal delivery—for the latter, mainly for ovarian cancers complicated by extensive ascites—, positioning an abdominal drainage tube and then infusing platinum-based chemotherapy drugs into the abdominal cavity are utilized.

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Written by Gong Chun
Oncology
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How is ovarian cancer treated?

Our treatment principle is that once an ovarian tumor is detected, surgical treatment should be performed. First and foremost, we need to confirm the diagnosis. Second, we should clarify the pathological staging of the ovarian cancer to guide the treatment. It's not a single approach; it's a comprehensive treatment plan. For example, if it is early stage and there are no surgical contraindications, we can proceed with surgical treatment. After the surgery, we can provide adjunctive chemotherapy. If surgery is not immediately feasible, we can also provide neoadjuvant therapy to reduce the stage before proceeding with ovarian cancer surgery. Moreover, there is now targeted therapy and immunotherapy for ovarian cancer, so it is a comprehensive treatment plan.

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Written by Liu Liang
Oncology
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Is chemotherapy effective after the recurrence of ovarian cancer?

After the recurrence of ovarian cancer, most patients can still benefit from chemotherapy again, as ovarian cancer itself is relatively sensitive to chemotherapy compared to other types of malignant tumors. If the recurrence occurs more than six months after the initial treatment, the same chemotherapy drugs used initially can still be chosen. However, if the recurrence happens within six months, the chemotherapy plan should include different drugs that were not used previously.

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Written by Liu Liang
Oncology
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How is ovarian cancer diagnosed?

Ultrasound or CT scans detecting ovarian masses, in combination with biopsy or cytological examination that identify cancer cells, can diagnose ovarian cancer. A common method of biopsy includes ultrasound-guided procedures or transvaginal cul-de-sac puncture biopsy of ovarian masses, enabling clear pathological confirmation. Additionally, exploratory laparotomy or early radical surgery for ovarian cancer patients can yield a postoperative pathological diagnosis of ovarian cancer. Moreover, the presence of ascites is a common symptom in ovarian cancer patients; finding cancer cells, especially adenocarcinoma, in ascites, coupled with significantly elevated tumor marker CA125, or ultrasound or CT imagery revealing ovarian masses, can also diagnose ovarian cancer.