Is chemotherapy effective after the recurrence of ovarian cancer?

Written by Liu Liang
Oncology
Updated on December 11, 2024
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After the recurrence of ovarian cancer, most patients can still benefit from chemotherapy again, as ovarian cancer itself is relatively sensitive to chemotherapy compared to other types of malignant tumors. If the recurrence occurs more than six months after the initial treatment, the same chemotherapy drugs used initially can still be chosen. However, if the recurrence happens within six months, the chemotherapy plan should include different drugs that were not used previously.

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Written by Liu Liang
Oncology
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Can ovarian cancer be cured?

Whether ovarian cancer can be cured depends on the clinical stage of the patient, as well as the patient's sensitivity to treatment, among other factors. If it is a case of early-stage ovarian cancer, curative surgery can be performed. After surgery, based on the pathology, it can be decided whether postoperative adjuvant radiotherapy or chemotherapy is necessary. Patients with early-stage ovarian cancer who undergo surgery or postoperative adjuvant radiotherapy and chemotherapy may have hope for a cure. However, if the cancer is discovered at a late stage where it has spread extensively, such as widespread metastasis to the pelvic area, or even to distant organs like the lungs or liver, then the treatment for these patients is primarily chemotherapy. A cure is not achievable; the treatment aims to alleviate symptoms and prolong the patient's life. Thus, for patients with late-stage ovarian cancer, treatment cannot achieve a curative purpose.

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Written by Liu Liang
Oncology
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How many years can one live with ovarian cancer?

The survival period of ovarian cancer patients is influenced by various factors including the specific stage of the cancer, whether there is residual tumor after surgery, the size of any residual tumor, the pathological type of the cancer, the presence of high-risk factors for recurrence such as vascular tumor thrombus, neural invasion, lymph node metastasis, etc., as well as the patient's age, overall condition, the presence of severe comorbidities, and the patient's response and sensitivity to treatments like radiotherapy and chemotherapy. Survival periods vary due to differences in stages and treatment sensitivities, meaning it cannot be generalized; there is significant individual variation in survival outcomes.

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Written by Liu Liang
Oncology
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How is ovarian cancer screened?

The most commonly used screening method for ovarian cancer is the B-ultrasound examination of the adnexa uteri. The B-ultrasound can detect ovarian masses and tumors, and when these are found, the possibility of ovarian cancer should be considered, necessitating further examinations for confirmation. Another method involves the tumor marker CA125, which is relatively sensitive and specific for epithelial ovarian cancer. Therefore, for ovarian cancer screening, we can perform a blood test for CA125 in conjunction with a B-ultrasound of the adnexa uteri.

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Written by Gong Chun
Oncology
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What are the symptoms of ovarian cancer?

Ovarian cancer often does not present symptoms in its early stages and can be detected during gynecological examinations. Secondly, as the tumor grows, it can cause abdominal swelling and discomfort, and abdominal masses may be felt during examinations. Ascites may also develop. The severity of these symptoms depends on the size and location of the tumor, the nearby organs it invades, and the histological type of the tumor. Thirdly, if the tumor infiltrates or compresses surrounding tissues, it can also lead to abdominal pain, back pain, and pain in the lower extremities. If it compresses the pelvic veins, swelling in the lower limbs may occur. If the tumor is functional, it can produce symptoms related to excess estrogen or androgen. In its later stages, the condition may manifest as cachexia and severe anemia, among other signs of a severe illness state.

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Written by Liu Liang
Oncology
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Ovarian cancer pain symptoms

In the early stages of ovarian cancer, the symptoms can be quite hidden, and the patient may not feel any discomfort at all. However, as the tumor grows and ascites develops, the patient typically may experience abdominal bloating, or a palpable mass may be felt in the pelvic or lower abdominal area. At this point, symptoms such as pain in the lower abdomen may occur, especially when there is a substantial amount of ascites, leading to clinical symptoms like abdominal bloating and pain. In even more advanced stages of ovarian cancer, the tumor may invade surrounding pelvic organs, potentially causing partial intestinal obstruction or symptoms of pelvic compression. With conditions like intestinal obstruction, there will be significant abdominal pain, possibly accompanied by vomiting, especially after eating, which can exacerbate the symptoms.