Will a tetanus wound heal?

Written by Tang Da Wei
General Surgery
Updated on March 21, 2025
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Tetanus wounds do not heal, and they contain a large amount of tetanus bacilli, which reproduce massively, leading to symptoms such as redness, pain, and even pus discharge in the affected area. Generally, these wounds cannot heal by themselves; even if the skin heals, the underlying and muscle tissues infected by tetanus can cause the skin to rupture and possibly accumulate pus. If a superficial wound is suspected to be infected with tetanus, it is necessary to promptly enlarge the wound, i.e., expand the surface wound, and rinse repeatedly with hydrogen peroxide and clean water to further kill the tetanus bacilli inside. At the same time, it is necessary to administer tetanus antitoxin, regularly observe the patient's clinical manifestations, and if necessary, administer tetanus antitoxin again after a period.

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chances of a person getting tetanus

Tetanus is a special type of infection that can enter the human body through skin, mucous membranes, or wounds and grows and reproduces in anaerobic conditions. The likelihood of a tetanus infection depends mainly on the depth and size of the wound, as well as what caused the wound. If the wound was caused by rusty nails or unclean sharp objects, and is both deep and large, the possibility of developing a tetanus infection is higher. Conversely, smaller or superficial wounds caused by relatively clean sharp objects are less likely to result in a tetanus infection.

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Written by Xu Jun Hui
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How long does a tetanus shot last?

After receiving a tetanus shot, it generally lasts for about six months. However, if you are injured again after six months and the wound is heavily contaminated, such as with contaminated soil or rust, and the wound is large and deep, it is advised to undergo tetanus treatment again. The purpose of the tetanus shot is to prevent infection by Clostridium tetani, which is an anaerobic bacterium. It tends to proliferate in anaerobic environments and in conditions of heavy contamination by rust and soil. Therefore, if after tetanus treatment the injury is relatively minor, shallow, and comparatively clean, it is sufficient to clean and dress the wound and keep it dry. If the wound is heavily contaminated, large, and deep, it is recommended to administer the tetanus shot again.

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Written by Liu Huan Huan
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Is tetanus administered intramuscularly or subcutaneously?

Tetanus is widely used clinically and is known as tetanus antitoxin, intended solely to prevent the clinical symptoms caused by infection with Clostridium tetani. Therefore, a skin test must be conducted before administering tetanus injections. The common skin test involves creating a skin wheal intradermally; if the skin test is negative, one can proceed with the tetanus antitoxin injection. The injection can be administered intramuscularly or subcutaneously. For example, the common sites include the deltoid attachment area on the upper arm for subcutaneous injections, and the deltoid or the lateral part of the buttock for intramuscular injections, among others. These are the injection sites for tetanus.

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How long does tetanus antibody last?

The duration of tetanus antibodies varies under two scenarios. The first is passive immunity, which is achieved through injections such as tetanus antitoxin or tetanus immunoglobulin. The duration of immunity provided by these injections is relatively short. Typically, tetanus antitoxin lasts about four days, while tetanus immunoglobulin can last up to three weeks. After this period, the levels of antibodies gradually decrease, and the body may no longer be protected. Therefore, a single application of tetanus antitoxin or immunoglobulin does not provide long-lasting immunity. The second scenario involves antibodies produced by active immunity, generally through the injection of a vaccine made from attenuated tetanus bacilli. Antibodies usually start to develop about ten days after vaccination, with levels gradually increasing over two to three months and remaining high. This type of immunity lasts up to about ten years, but it is not lifelong. Regular boosters, guided by relevant tests, are required to maintain immunity.

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How to administer an injection if the tetanus skin test is negative

A negative tetanus skin test indicates that there is no allergy to tetanus antitoxin, and 1500 to 3000 units of tetanus antitoxin can be directly administered via intramuscular injection in the upper arm or buttock. If the wound is heavily contaminated or the injection is not timely, the dose may be doubled or tripled at discretion, and it is also necessary to clean and dress the wound. The purpose of administering tetanus antitoxin via intramuscular injection is to prevent infection by Clostridium tetani. Therefore, patients with heavily contaminated or deep wounds must receive tetanus antitoxin treatment.