How long does a tetanus shot last?

Written by Xu Jun Hui
General Surgery
Updated on November 21, 2024
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After receiving a tetanus shot, it generally lasts for about six months. However, if you are injured again after six months and the wound is heavily contaminated, such as with contaminated soil or rust, and the wound is large and deep, it is advised to undergo tetanus treatment again. The purpose of the tetanus shot is to prevent infection by Clostridium tetani, which is an anaerobic bacterium. It tends to proliferate in anaerobic environments and in conditions of heavy contamination by rust and soil. Therefore, if after tetanus treatment the injury is relatively minor, shallow, and comparatively clean, it is sufficient to clean and dress the wound and keep it dry. If the wound is heavily contaminated, large, and deep, it is recommended to administer the tetanus shot again.

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Written by Liu Huan Huan
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How is tetanus diagnosed?

The diagnosis of tetanus requires comprehensive consideration. If the patient has a history of trauma with skin or mucosal wounds, and shows signs of muscle spasms, such as difficulty opening the mouth, stiffening of the neck, and increased reflexes, the possibility of a tetanus infection should be considered. Further, a culture of the wound can be conducted to see if Clostridium tetani can be cultured. If the culture is positive, a definitive diagnosis can be made. Additionally, tetanus needs to be differentiated from other diseases such as purulent meningitis, rabies, epilepsy, hysteria, and so on.

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Is tetanus administered intramuscularly or subcutaneously?

Tetanus is widely used clinically and is known as tetanus antitoxin, intended solely to prevent the clinical symptoms caused by infection with Clostridium tetani. Therefore, a skin test must be conducted before administering tetanus injections. The common skin test involves creating a skin wheal intradermally; if the skin test is negative, one can proceed with the tetanus antitoxin injection. The injection can be administered intramuscularly or subcutaneously. For example, the common sites include the deltoid attachment area on the upper arm for subcutaneous injections, and the deltoid or the lateral part of the buttock for intramuscular injections, among others. These are the injection sites for tetanus.

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Is tetanus fatal?

Tetanus infection is quite frightening, with current statistics showing that the mortality rate of tetanus infections can be as high as 40%, and about a million people die from tetanus globally each year. The current principle is to promptly inject tetanus antitoxin or tetanus immunoglobulin for sharp, deep wounds. For tetanus infection, the main symptoms manifest as local or systemic muscle rigidity and spasms. The incubation period varies; if a tetanus vaccination has been previously administered, or depending on the infection and treatment of the wound, the severity of the onset can differ. The prodromal period typically presents symptoms like dizziness, headache, heightened reflexes, restlessness, and possible difficulty opening the mouth; during the convulsive phase, there is continuous muscle contraction, eventually causing persistent spasms in the diaphragm and intercostal muscles.

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Will a scrape lead to tetanus?

When a tetanus infection occurs, the wound is generally quite deep, for instance, reaching the subcutaneous fat or even the muscle layer in severe cases. Such deep wounds can create an anaerobic environment, which is conducive for the growth and reproduction of Clostridium tetani, an anaerobic bacterium. This bacterium produces exotoxins, primarily the tetanospasmin, which causes the associated clinical symptoms in patients. If it's merely a scrape or a superficial wound, tetanus infection is unlikely. Clinically, what is needed for such abrasions is to disinfect the area with iodine and then bandage it appropriately.

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Initial symptoms of tetanus

The bacterium that causes tetanus is Clostridium tetani, which is an anaerobic bacterium. If the wound is deep and enclosed in an environment lacking oxygen, it creates a suitable environment for the growth and reproduction of Clostridium tetani. Its incubation period is generally around one week. Early symptoms may include general fatigue, localized muscle tension, and uncontrollable spasms. The first muscles affected are usually the facial chewing muscles, and it can then progress to intense, spasmodic contractions of muscles throughout the body, and even cause fractures. Mild stimuli such as light, sound, or drinking water can trigger and worsen these symptoms, somewhat similar to rabies. However, a characteristic feature of tetanus is that the patient remains mentally clear. Most patients may die from respiratory spasms leading to asphyxiation, heart failure, or lung infections.