When to get a tetanus shot

Written by Tang Da Wei
General Surgery
Updated on February 24, 2025
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A tetanus shot is generally recommended to be administered immediately after an injury for the best efficacy. If given within 12 or 24 hours, it still provides certain preventive effects. The tetanus shot mainly consists of tetanus antitoxin and represents passive immunization. It is usually advised in cases of deep wounds with small surface areas that can create anaerobic conditions inside. If tetanus bacillus is present in the wound and proliferates massively under anaerobic conditions, the patient may exhibit symptoms such as opisthotonos, asphyxiation, or even death. Therefore, it is necessary to administer tetanus antitoxin for prevention.

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What should I do if I am allergic to tetanus shots?

The full name of the tetanus shot is tetanus antitoxin serum, which is mainly made from horse serum and has certain allergenic properties. If a patient is allergic to tetanus antitoxin serum, desensitization injections can be used, which involves gradually injecting one milliliter of the tetanus antitoxin serum into the body in four or more sessions, with each injection spaced about twenty to thirty minutes apart. After each injection, it is important to closely observe the patient's reaction, including checking for signs of itching in the nose, hives throughout the body, or difficulty breathing. If any of these symptoms occur, emergency treatment should be administered. If the injections of tetanus antitoxin serum cannot be completed multiple times, or if the patient is unwilling to accept this method of injection, tetanus immunoglobulin can be administered instead of tetanus antitoxin serum. Tetanus immunoglobulin does not require a sensitivity test and can be directly injected into the body without causing an allergic reaction, although it is more expensive.

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Can I eat before getting a tetanus shot?

Tetanus shots are a common preventive measure. Once symptoms appear, they can directly impact many aspects of the body, and further judgement is based on specific conditions. Generally, if there are no special problems, a normal diet is acceptable. However, during eating, it is advisable to avoid spicy and irritating foods, as such foods can directly affect certain functions or enhance immunity, which is the most important treatment approach. Additionally, it is necessary to consider the patient's physical condition to assess whether the tetanus bacillus injection can still be effective beforehand, or if a light diet is required. This can provide a very precise approach, which is more beneficial for the prevention of subsequent vaccinations.

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Which part of the body is the tetanus shot administered?

Tetanus shots are administered in the buttocks or the muscular part of the upper arm, typically given as a muscle injection. Tetanus shots must not be administered intravenously. Before administering a tetanus shot, a skin test is conducted. If the skin test is positive, it is necessary to switch to a tetanus immune globulin that does not require a skin test; if the skin test is negative, a muscle injection can be performed. Tetanus is caused by the colonization of Clostridium tetani in the human body, producing neurotoxins, leading to a specific type of infection. Therefore, if the wound is deep and heavily contaminated, it is essential to promptly treat with a tetanus shot.

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Initial symptoms of tetanus

The bacterium that causes tetanus is Clostridium tetani, which is an anaerobic bacterium. If the wound is deep and enclosed in an environment lacking oxygen, it creates a suitable environment for the growth and reproduction of Clostridium tetani. Its incubation period is generally around one week. Early symptoms may include general fatigue, localized muscle tension, and uncontrollable spasms. The first muscles affected are usually the facial chewing muscles, and it can then progress to intense, spasmodic contractions of muscles throughout the body, and even cause fractures. Mild stimuli such as light, sound, or drinking water can trigger and worsen these symptoms, somewhat similar to rabies. However, a characteristic feature of tetanus is that the patient remains mentally clear. Most patients may die from respiratory spasms leading to asphyxiation, heart failure, or lung infections.

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How to avoid tetanus with minor wounds

If minor wounds are not properly handled, they can lead to serious problems, including tetanus. Treatment for minor wounds should be based on the integrity of the skin, the depth of the wound, and whether the object causing the wound was rusty. For simple minor wounds where the integrity of the skin is maintained and only abrasions are present, disinfection of the affected skin area may suffice. If the wound has compromised the integrity of the skin and is deep, especially if caused by rusty, sharp objects, it is necessary to thoroughly remove any foreign materials, clean the wound, and suture it. Dressing changes might be required, along with tetanus vaccination to prevent tetanus infection.