What should I do if I am allergic to tetanus shots?

Written by Wang Xiang Li
Emergency Medicine
Updated on November 09, 2024
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The full name of the tetanus shot is tetanus antitoxin serum, which is mainly made from horse serum and has certain allergenic properties. If a patient is allergic to tetanus antitoxin serum, desensitization injections can be used, which involves gradually injecting one milliliter of the tetanus antitoxin serum into the body in four or more sessions, with each injection spaced about twenty to thirty minutes apart. After each injection, it is important to closely observe the patient's reaction, including checking for signs of itching in the nose, hives throughout the body, or difficulty breathing. If any of these symptoms occur, emergency treatment should be administered. If the injections of tetanus antitoxin serum cannot be completed multiple times, or if the patient is unwilling to accept this method of injection, tetanus immunoglobulin can be administered instead of tetanus antitoxin serum. Tetanus immunoglobulin does not require a sensitivity test and can be directly injected into the body without causing an allergic reaction, although it is more expensive.

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Can tetanus be cured?

Tetanus is an infectious disease that can be cured. Generally, tetanus is considered to be caused by the infection of Clostridium tetani, which produces toxins. Clinically, it is mainly characterized by muscle tension and rigidity, such as lockjaw, difficulty opening the mouth, risus sardonicus, stiff neck, and opisthotonos. In severe cases, it can involve the respiratory muscles and diaphragm, causing difficulty breathing, respiratory arrest, and even cardiac arrest. When patients with tetanus receive standardized and systematic hospital treatment, and if there are no severe complications, the vast majority of patients can be cured.

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Do you need a tetanus shot for a scraped skin?

Tetanus bacterial infection generally refers to relatively deeper wounds. A deeper wound creates an anaerobic environment locally, where tetanus-causing bacteria can reproduce and grow, leading to infection. If the wound is just a scrape and not deep, it's less likely to form an anaerobic environment. In such cases, the likelihood of developing tetanus is extremely low. From personal experience, if it's just a minor scrape, simply disinfecting the area with iodine is sufficient; there is generally no need for a tetanus antitoxin injection.

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Is tetanus serious?

Firstly, it must be acknowledged that tetanus is a curable, specific infectious disease. When the human body is infected with tetanus, the initial symptoms mainly include dizziness, headache, fatigue, decreased appetite, difficulty in chewing, muscle soreness, or some heightened reflexes. As the condition worsens, muscle spasms and rigidity can occur, such as grimacing, lockjaw, difficulty opening the mouth, stiff neck, and opisthotonos. In severe cases, there may be difficulty breathing, respiratory arrest, and even cardiac arrest. If someone is suffering from tetanus, they should promptly seek systematic and formal treatment at a hospital. As long as there are no serious complications, the vast majority of tetanus patients can be cured, so tetanus is not as frightening as it may seem.

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Will a scrape lead to tetanus?

When a tetanus infection occurs, the wound is generally quite deep, for instance, reaching the subcutaneous fat or even the muscle layer in severe cases. Such deep wounds can create an anaerobic environment, which is conducive for the growth and reproduction of Clostridium tetani, an anaerobic bacterium. This bacterium produces exotoxins, primarily the tetanospasmin, which causes the associated clinical symptoms in patients. If it's merely a scrape or a superficial wound, tetanus infection is unlikely. Clinically, what is needed for such abrasions is to disinfect the area with iodine and then bandage it appropriately.

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How long does it take for tetanus to develop?

Tetanus is a specific type of infection caused by the toxin produced by the growth and reproduction of Clostridium tetani, which enters the body through damaged skin and mucous membranes and thrives in an anaerobic environment. Clinically, it is mainly characterized by lockjaw, muscle rigidity, and muscle spasms. After being infected with tetanus, people generally show symptoms within seven to eight days; in quick cases, symptoms can appear within twenty-four hours, while in longer scenarios, the onset can take several months or even years.