What should I do if I am allergic to tetanus shots?

Written by Wang Xiang Li
Emergency Medicine
Updated on November 09, 2024
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The full name of the tetanus shot is tetanus antitoxin serum, which is mainly made from horse serum and has certain allergenic properties. If a patient is allergic to tetanus antitoxin serum, desensitization injections can be used, which involves gradually injecting one milliliter of the tetanus antitoxin serum into the body in four or more sessions, with each injection spaced about twenty to thirty minutes apart. After each injection, it is important to closely observe the patient's reaction, including checking for signs of itching in the nose, hives throughout the body, or difficulty breathing. If any of these symptoms occur, emergency treatment should be administered. If the injections of tetanus antitoxin serum cannot be completed multiple times, or if the patient is unwilling to accept this method of injection, tetanus immunoglobulin can be administered instead of tetanus antitoxin serum. Tetanus immunoglobulin does not require a sensitivity test and can be directly injected into the body without causing an allergic reaction, although it is more expensive.

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Written by Xu Jun Hui
General Surgery
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Can I get a tetanus shot in the emergency room?

The injection of tetanus shots is performed in the emergency department of regular hospitals. Tetanus shots are divided into tetanus toxoid, which requires a skin test, and tetanus immunoglobulin, which does not require a skin test. If the skin test for tetanus toxoid is positive, indicating an allergy, it cannot be injected, and must be replaced with the slightly more expensive tetanus immunoglobulin. It is generally recommended to administer the injection within 24 hours after injury to prevent infection by Clostridium tetani. Clostridium tetani is an anaerobic bacterium. It is necessary to administer tetanus treatment for injuries that are deep, in anaerobic conditions, contaminated, heavily contaminated with soil, rust, open fractures, etc., since these conditions can be conducive to tetanus infection.

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Written by Li Jin Quan
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How long is the incubation period for tetanus generally?

Tetanus is a specific infection caused by the bacterium Clostridium tetani entering the human body through wounds in the skin and mucous membranes, proliferating massively in an anaerobic environment, and producing toxins. It is primarily characterized clinically by lockjaw and episodic or sustained muscle spasms. The incubation period of tetanus is usually seven to eight days, but it can be as short as twenty-four hours or as long as several months, or even years.

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Written by Liu Huan Huan
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Can superficial wounds get tetanus?

Tetanus infection commonly occurs in deeper wounds, for instance, wounds that reach the subcutaneous fat layer, and in severe cases, even the muscle layer. Such deep wounds can create an anaerobic environment, and Clostridium tetani, an anaerobic bacterium, thrives in this oxygen-free environment. It can secrete various bacterial toxins, thereby causing tetanus in patients. Therefore, tetanus generally occurs in deep wounds. For superficial wounds, the chance of contracting tetanus is almost zero if the wound is properly disinfected locally.

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Written by Gao Tian
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What should I do if the tetanus skin test is positive?

For patients, what to do if there is a positive tetanus skin test? Generally if it's positive, you can undergo desensitization injections or use anti-protein drugs. Therefore, in such cases, getting a tetanus injection is also a preventative measure against infection. It's recommended to visit a surgeon to complete relevant examinations and then decide on the next steps. At the same time, thorough debridement and disinfection should be carried out. Afterwards, rest, pay attention to diet by avoiding spicy and irritating foods, maintain cleanliness and dryness, change dressings regularly, and have regular follow-ups. With proper control, recovery is possible.

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Written by Li Jin Quan
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How long does it take for tetanus to develop?

The pathogen we refer to as tetanus is Clostridium tetani. It enters the body through broken skin or mucous membranes and proliferates extensively in an anaerobic environment, producing toxins that cause a characteristic infection known as tetanus. After infection, the incubation period of tetanus varies; typically, symptoms appear within seven to eight days, but they can manifest as quickly as within twenty-four hours or take several months or even years to develop.