What should I do if the tetanus skin test is positive?

Written by Gao Tian
General Surgery
Updated on February 04, 2025
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For patients, what to do if there is a positive tetanus skin test? Generally if it's positive, you can undergo desensitization injections or use anti-protein drugs. Therefore, in such cases, getting a tetanus injection is also a preventative measure against infection. It's recommended to visit a surgeon to complete relevant examinations and then decide on the next steps. At the same time, thorough debridement and disinfection should be carried out. Afterwards, rest, pay attention to diet by avoiding spicy and irritating foods, maintain cleanliness and dryness, change dressings regularly, and have regular follow-ups. With proper control, recovery is possible.

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Written by Gao Sen
General Surgery
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The likelihood of a wound being infected with tetanus

Tetanus is a specific infection often associated with trauma, with a high contamination rate of tetanus bacillus in traumatic wounds. On the battlefield, the contamination rate can reach 25% to 80%, although the incidence of tetanus in contaminated wounds is only about 10% to 20%. This suggests that other factors are necessary for the disease to occur, with the main factor being an anaerobic environment. If the wound is deep, with a small external opening, and contains necrotic tissue, blood clots, or is too tightly packed, this can lead to local ischemia. Additionally, if there is a co-infection with aerobic bacteria consuming residual oxygen in the wound, it creates an anaerobic environment conducive to the growth of the bacteria, thus increasing the likelihood of tetanus infection in the wound.

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Written by Zhang Peng
General Surgery
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Symptoms of Tetanus

What are the symptoms of tetanus? Generally, the prodromal symptoms include overall weakness, headache, difficulty swallowing, or limited movement of the head and neck. If the condition progresses further, there may be typical symptoms such as difficulty opening the mouth or tense jaw muscles, leading to muscle spasms in the limbs, possibly causing spasms of the larynx, which can lead to breathing difficulties or even suffocation. Hence, it is a particularly severe manifestation. Some individuals may experience generalized tonic muscle spasms throughout the body, a milder manifestation with a typically longer incubation period. Therefore, in the treatment of tetanus, proactive active immunization should be pursued.

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Written by Ma Xian Shi
General Surgery
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How long does it take for tetanus to develop?

Tetanus is an acute, specific infection caused by the invasion of Clostridium tetani into a human wound, where it grows and reproduces, producing toxins. Tetanus is a Gram-positive, anaerobic, spore-forming bacillus that is widely present in the external environment. Tetanus occurs only when tetanus bacillus grows and reproduces locally in a wound and produces exotoxins, which are the cause of the disease. The toxins of tetanus include spasm toxin and hemolysin. The incubation period of tetanus generally ranges from six to ten days. In some cases, it can occur within 24 hours or take as long as 20 to 30 days, or even months, particularly following the removal of foreign bodies or shrapnel. Neonatal tetanus generally occurs seven days after umbilical cord separation, clinically also known as the "seven-day wind." Generally, the shorter the duration of the incubation period or prodromal symptoms, the more severe the symptoms and the higher the mortality rate.

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Written by Ai Bing Quan
General Surgery
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Where to get a tetanus shot?

Tetanus can be treated in any department, but generally, after an injury, one would first go to the emergency room. Therefore, tetanus is very common in emergency medicine. Tetanus is a type of anaerobic bacterium that is ubiquitous in nature. If a person has a wound that is small and deep, the internal environment can become anaerobic, which easily leads to rapid proliferation of tetanus. At this point, it is necessary to inject tetanus immunoglobulin into such wounds. It is best done within 24 hours because after a long period, the tetanus bacillus might have already proliferated in the wound. A skin test should be performed before the injection, and the injection can only proceed if the skin test is negative. If the wound is relatively large and severe, it generally will not be infected by tetanus bacillus.

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Written by Xu Jun Hui
General Surgery
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What is the function of a tetanus shot?

A tetanus shot is used to prevent infection by the tetanus bacillus, because certain wounds, such as those that are deep and small or heavily contaminated, are susceptible to colonization by the tetanus bacillus. This bacterium thrives in anaerobic conditions. It typically enters the body through the skin or mucous membranes and produces toxins that cause muscle spasms, a specific type of infection. This often leads to symptoms like lockjaw, spontaneous spasms, and compulsory spasms, commonly affecting the jaw muscles, abdominal muscles, and limbs, and can be life-threatening. Therefore, for wounds that are heavily contaminated, deep, and small, it is essential to administer anti-tetanus treatment.