What are the symptoms of tetanus? Generally, the prodromal symptoms include overall weakness, headache, difficulty swallowing, or limited movement of the head and neck. If the condition progresses further, there may be typical symptoms such as difficulty opening the mouth or tense jaw muscles, leading to muscle spasms in the limbs, possibly causing spasms of the larynx, which can lead to breathing difficulties or even suffocation. Hence, it is a particularly severe manifestation. Some individuals may experience generalized tonic muscle spasms throughout the body, a milder manifestation with a typically longer incubation period. Therefore, in the treatment of tetanus, proactive active immunization should be pursued.