How to desensitize 0.75ml tetanus?

Written by Li Jin Quan
General Surgery
Updated on September 14, 2024
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Usually, the tetanus desensitization injection is administered in four doses. We start with 0.1 ml of tetanus toxoid plus 0.9 ml of saline diluted to 1 ml for intramuscular injection. After 20 minutes, we use 0.2 ml of tetanus toxoid plus 0.8 ml of saline diluted to 1 ml for another intramuscular injection. Twenty minutes later, we inject 0.3 ml of tetanus toxoid plus 0.7 ml of saline diluted to 1 ml intramuscularly. After another 20 minutes, we dilute the remaining tetanus toxoid with saline to 1 ml for the final intramuscular injection. After the injection, we observe for 30 minutes; if there is no allergic reaction, then it is complete.

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Written by Ai Bing Quan
General Surgery
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What department should I go to for tetanus?

Tetanus is a special type of infection that should be treated through routine surgery or emergency surgery. It is caused by the tetanus bacillus, an anaerobic bacterium typically found in feces. Tetanus is easily contracted after an injury, especially in deep wounds. Clinically, tetanus manifests initially with difficulty in opening the mouth, followed by a grimacing smile, convulsions, and respiratory difficulties later on. Preventive measures include going to the hospital immediately after an injury to have the wound cleaned at the department of general surgery or emergency surgery and concurrently receiving a tetanus serum injection.

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Written by Tang Da Wei
General Surgery
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Is the risk of tetanus high?

Tetanus occurs infrequently, but once it appears, the condition can be very severe and may lead to death if not treated promptly. Tetanus infection is mainly caused by infection with the tetanus bacillus. The tetanus bacillus is an anaerobic bacterium that exists everywhere in nature. If the wound is very deep with a small surface area, and the conditions inside the wound become anaerobic, if the tetanus bacilli inside the wound are not thoroughly cleaned, it could lead to the rapid reproduction of the tetanus bacilli, releasing tetanus toxin and causing a tetanus infection in the patient.

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Written by Liu Huan Huan
General Surgery
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Criteria for a Positive Tetanus Diagnosis

After a person is injured, if the wound reaches deeper parts such as the subcutaneous fat layer or even the muscle layer, it is essential to administer tetanus antitoxin to prevent infection from tetanus bacillus. Before injecting the tetanus antitoxin, a skin test must be conducted to prevent allergies and anaphylactic shock. Generally, after injecting the test agent, observations are made for 30 minutes. If there is an enlargement of the wheal, redness and swelling that infiltrates surrounding areas, and the patient feels itching, it indicates a positive result.

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Written by Ai Bing Quan
General Surgery
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chances of a person getting tetanus

Tetanus is a special type of infection that can enter the human body through skin, mucous membranes, or wounds and grows and reproduces in anaerobic conditions. The likelihood of a tetanus infection depends mainly on the depth and size of the wound, as well as what caused the wound. If the wound was caused by rusty nails or unclean sharp objects, and is both deep and large, the possibility of developing a tetanus infection is higher. Conversely, smaller or superficial wounds caused by relatively clean sharp objects are less likely to result in a tetanus infection.

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Written by Li Jin Quan
General Surgery
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Do you still need a skin test for tetanus allergy?

Under normal circumstances, if there is an allergy to tetanus, a skin test is not required. If tetanus vaccination is indeed necessary, human immunoglobulin can be injected, and this does not require a skin test. 250 units can be injected directly. Additionally, tetanus antitoxin desensitization injections can be used. The so-called desensitization injection involves diluting 1500 units of tetanus antitoxin into doses of 0.1 ml, 0.2 ml, 0.3 ml, and 0.4 ml, totaling 1 ml, and administering it in four doses, each 20 minutes apart. After the injections are completed, an observation period of 30 minutes is required to ensure there are no adverse reactions before the patient can leave.