How to desensitize 0.75ml tetanus?

Written by Li Jin Quan
General Surgery
Updated on September 14, 2024
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Usually, the tetanus desensitization injection is administered in four doses. We start with 0.1 ml of tetanus toxoid plus 0.9 ml of saline diluted to 1 ml for intramuscular injection. After 20 minutes, we use 0.2 ml of tetanus toxoid plus 0.8 ml of saline diluted to 1 ml for another intramuscular injection. Twenty minutes later, we inject 0.3 ml of tetanus toxoid plus 0.7 ml of saline diluted to 1 ml intramuscularly. After another 20 minutes, we dilute the remaining tetanus toxoid with saline to 1 ml for the final intramuscular injection. After the injection, we observe for 30 minutes; if there is no allergic reaction, then it is complete.

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Written by Gao Sen
General Surgery
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The likelihood of a wound being infected with tetanus

Tetanus is a specific infection often associated with trauma, with a high contamination rate of tetanus bacillus in traumatic wounds. On the battlefield, the contamination rate can reach 25% to 80%, although the incidence of tetanus in contaminated wounds is only about 10% to 20%. This suggests that other factors are necessary for the disease to occur, with the main factor being an anaerobic environment. If the wound is deep, with a small external opening, and contains necrotic tissue, blood clots, or is too tightly packed, this can lead to local ischemia. Additionally, if there is a co-infection with aerobic bacteria consuming residual oxygen in the wound, it creates an anaerobic environment conducive to the growth of the bacteria, thus increasing the likelihood of tetanus infection in the wound.

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Written by Li Jin Quan
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Does tetanus cause fever?

When a person is infected with tetanus, the early symptoms mainly include dizziness, headache, fatigue, decreased appetite, weak chewing, sore jaw muscles, some muscle tension, or some hyperactive reflexes. As the condition worsens, typical clinical manifestations occur, such as difficulty opening the mouth, a sardonic smile, opisthotonos or neck stiffness, muscle spasms, muscle rigidity, and in severe cases, respiratory weakness or respiratory arrest. Some patients may develop a fever after being infected with tetanus. Therefore, some tetanus patients do show symptoms of fever.

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Written by Zhang Peng
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How long does the tetanus shot last?

The duration of the effectiveness of a tetanus shot depends on whether tetanus antitoxin or tetanus immunoglobulin is administered following a suspected tetanus infection. Both types are forms of artificial passive immunity, providing immediate specific immunity after injection, mainly for treatment or emergency prevention. The metabolism and immune duration of these two injections vary: generally, tetanus antitoxin lasts about seven days, while tetanus immunoglobulin can last up to three weeks. Therefore, the specific duration of the effectiveness of a tetanus shot must be determined based on the individual injection circumstances. For suspected tetanus infections, it is generally advised to administer the injection as soon as possible. It's not that the injection will be ineffective if administered after a certain time, but rather that effective prevention before the onset of the disease can still be beneficial.

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Written by Li Jin Quan
General Surgery
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What should I do if I am allergic to tetanus?

Mild symptoms of tetanus allergy mainly manifest as skin redness, itching, and the appearance of rashes, some of which occur a few days after the tetanus injection, with redness and itching at the injection site or the appearance of some rashes. Severe tetanus allergies can cause chest tightness, irritability, pale complexion, profuse sweating, low blood pressure, and slow pulse. In severe cases, it can lead to cessation of heartbeat and breathing. Once an allergic reaction to tetanus occurs, the injection of tetanus should be immediately discontinued, a venous pathway should be established, and aggressive treatment with adrenaline, dexamethasone, and calcium agents should be administered for the allergy.

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Written by Li Jin Quan
General Surgery
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Is tetanus serious?

Firstly, it must be acknowledged that tetanus is a curable, specific infectious disease. When the human body is infected with tetanus, the initial symptoms mainly include dizziness, headache, fatigue, decreased appetite, difficulty in chewing, muscle soreness, or some heightened reflexes. As the condition worsens, muscle spasms and rigidity can occur, such as grimacing, lockjaw, difficulty opening the mouth, stiff neck, and opisthotonos. In severe cases, there may be difficulty breathing, respiratory arrest, and even cardiac arrest. If someone is suffering from tetanus, they should promptly seek systematic and formal treatment at a hospital. As long as there are no serious complications, the vast majority of tetanus patients can be cured, so tetanus is not as frightening as it may seem.