Methods of Diagnosing Parkinson's Disease

Written by Zhou Yan
Geriatrics
Updated on February 25, 2025
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In the auxiliary examinations for Parkinson's disease, routine laboratory tests as well as CT and MRI scans of the head generally show no specific changes. However, in molecular imaging, PET CT can reveal a significant decrease in striatal dopamine transporter. For olfactory tests, over 80% of Parkinson's patients exhibit olfactory dysfunction. Doppler ultrasound can also detect a significant enhancement of the substantia nigra signal. Despite these advancements in auxiliary examinations, diagnosis in patients with Parkinson's disease still primarily relies on clinical evaluation. According to the 2015 criteria, the diagnostic standards are still based on clinical diagnosis, which includes two main points: first, bradykinesia, where voluntary movements are slow and the speed and amplitude of repetitive movements progressively decrease; second, at least one of the following two manifestations must be present: muscular rigidity or resting tremor.

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Written by Zhang Hui
Neurology
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What to do about constipation in Parkinson's disease?

Among Parkinson's disease patients, constipation is a very common clinical symptom. In fact, many patients have experienced constipation for many years before the onset of Parkinson's disease symptoms, mainly due to the impact on some autonomic nerves in the intestines. For Parkinson's patients experiencing constipation, the main suggestions are: First, be sure to drink plenty of water. Drinking enough water can sufficiently lubricate the intestines and facilitate smoother bowel movements. Second, be sure to eat plenty of fresh vegetables and fruits. Vegetables and fruits are rich in vitamin C and can promote gastrointestinal motility. Additionally, it is recommended for patients to eat more bananas, as bananas have an evident laxative effect. Also, eat less of certain foods that can dry out the stool, such as sweet potatoes and chestnuts. If necessary, patients can be given laxative medications, and if bowel movements are extremely difficult, enemas can also be administered.

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Written by Zhang Hui
Neurology
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Can Parkinson's patients drink alcohol?

It is recommended that patients with Parkinson's disease avoid drinking alcohol. This is because the condition in Parkinson's patients is caused by the death of certain neurons in the substantia nigra of the midbrain. It is well-known that alcohol has a direct damaging effect on neurons. Therefore, drinking alcohol could potentially worsen the symptoms of Parkinson's disease, and it is advised not to drink alcohol. Additionally, patients with Parkinson's disease are prone to panic and unstable gait. If alcohol consumption affects the function of the cerebellum, it will exacerbate the patient's instability in walking, making them very prone to falls and potentially causing complications such as fractures. Furthermore, drinking alcohol can lead to orthostatic hypotension, which is a lower blood pressure when standing up. Parkinson's disease itself can also cause this type of orthostatic hypotension, and the combination of the two can cause a significant drop in blood pressure in patients, posing a risk when standing.

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Written by Zhang Hui
Neurology
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Early symptoms of Parkinson's disease

Parkinson's disease in its early stages may primarily manifest as clumsiness in limb movement, especially in fine motor skills, such as difficulty in wrapping dumplings, rolling dumpling wrappers, or slow buttoning, which are clinical signs of early symptoms. Some patients may initially experience slight trembling in the limbs, which is generally more pronounced during rest and relaxation and diminishes during activity. Additionally, some individuals with early Parkinson's disease primarily exhibit non-motor symptoms, such as constipation, depression, reduced sense of smell, and may also experience rapid eye movement sleep behavior disorder, characterized by shouting and physical actions like punching or kicking during sleep.

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Written by Zhou Yan
Geriatrics
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What should be avoided in the diet for Parkinson's disease?

For patients with Parkinson's disease, we advocate comprehensive treatment and full-course management. Drug treatment is the core treatment method, while surgical treatment can supplement drug therapy. Physical rehabilitation and psychological therapy should also be conducted. What should patients with Parkinson's disease avoid eating? Generally, patients with Parkinson's disease are prone to constipation. Therefore, we should avoid consuming spicy and greasy foods that may lead to constipation, and try to eat vegetables and fruits to keep the bowel movements regular.

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Written by Zhang Hui
Neurology
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What tests are done for Parkinson's disease?

Parkinson's disease is a degenerative disease of the nervous system. Many patients report that numerous examinations did not identify a clear cause of the disease, which is typical of this condition due to the lack of very effective diagnostic methods. Patients' symptoms gradually worsen, manifesting as motor slowness, limb tremors, muscle rigidity, and other clinical signs. There are also symptoms such as constipation and dizziness. Generally, the following examinations are recommended for Parkinson's disease: First, complete a cranial MRI scan. The primary purpose of a cranial MRI is to exclude other causes of Parkinson's-like symptoms, such as cerebral thrombosis, brain tumors, or inflammation. Second, perform olfactory tests, as some patients may experience a significant reduction in their sense of smell early on. Third, conduct induced sleep monitoring, since some patients may have prominent sleep disorders. Additionally, it is suggested to perform striatal dopaminergic transporter imaging, a type of DAT scan. Although this scan is quite expensive, it can clearly reflect the function of the striatum.