Can Parkinson's patients drink alcohol?

Written by Zhang Hui
Neurology
Updated on September 12, 2024
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It is recommended that patients with Parkinson's disease avoid drinking alcohol. This is because the condition in Parkinson's patients is caused by the death of certain neurons in the substantia nigra of the midbrain. It is well-known that alcohol has a direct damaging effect on neurons. Therefore, drinking alcohol could potentially worsen the symptoms of Parkinson's disease, and it is advised not to drink alcohol. Additionally, patients with Parkinson's disease are prone to panic and unstable gait. If alcohol consumption affects the function of the cerebellum, it will exacerbate the patient's instability in walking, making them very prone to falls and potentially causing complications such as fractures. Furthermore, drinking alcohol can lead to orthostatic hypotension, which is a lower blood pressure when standing up. Parkinson's disease itself can also cause this type of orthostatic hypotension, and the combination of the two can cause a significant drop in blood pressure in patients, posing a risk when standing.

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Neurology
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Early symptoms of Parkinson's disease

The early symptoms of Parkinson's disease primarily include weakness of limbs on one side, resting tremors, and bradykinesia, among others. As the disease progresses, patients will display typical Parkinson's symptoms, including a shuffling gait, reduced facial expressions, decreased sense of smell, orthostatic hypotension, anxiety and depression, cognitive decline, constipation, frequent urination, etc. Therefore, when these symptoms appear, the possibility of Parkinson's disease should be considered. Patients need to promptly visit the neurology department of a hospital for complete testing such as routine blood tests, urinalysis, MRI of the skull, and if necessary, cerebrospinal fluid analysis through lumbar puncture to confirm the diagnosis. Once diagnosed, treatment with anti-Parkinson's medication should be started as soon as possible. Commonly used medications include Levodopa, dopamine receptor agonists, monoamine oxidase inhibitors, Vitamin B6, and more.

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Written by Liu Hong Mei
Neurology
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Parkinson's disease Braak staging

Parkinson's disease Braak staging is generally divided into five stages: Stage 1 refers to unilateral symptoms only, such as tremors or stiffness in one hand or one foot, with symptoms confined to one side of the body and not crossing the midline. Stage 2 refers to mild symptoms on both sides, such as tremors in both hands or throughout the body, but without impairment of balance. Stage 3 refers to more pronounced bilateral symptoms, such as difficulty lifting legs, taking small shuffling steps, leaning forward, or instability when holding a bowl while eating, but capable of living normally. Stage 4 refers to the loss of most of the ability for autonomous activity. Stage 5 refers to a complete loss of the ability to live independently.

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Written by Zhang Hui
Neurology
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How does one get Parkinson's disease?

Parkinson's disease is a degenerative disease of the nervous system. The actual mechanism of the disease is not very clear, and its fundamental cause has not yet been identified. It is generally believed that Parkinson's disease is mainly caused by the following factors. First, genetic factors. Some cases of Parkinson's disease have a clear familial tendency, where patients may experience mutations in synaptic nuclear protein genes, leading to abnormal aggregation of these proteins. This abnormal aggregation can damage the neurons in the substantia nigra of the midbrain, leading to Parkinson's disease. Second, there are some external factors related to sporadic cases of Parkinson's. These may be closely related to oxidative stress, trauma, poisoning, or an excessive stress response of the body. However, the specific cause is not very clear. Parkinson's disease, which causes symptoms such as bradykinesia, tremors, and rigidity, requires active treatment to improve the quality of life of the patients.

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Written by Zhang Hui
Neurology
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What department should you go to for Parkinson's disease?

Registration for Parkinson's disease should be in the Department of Neurology, as Parkinson's disease is a common disorder within neurology, so seeing a neurologist is sufficient. Parkinson's disease is a degenerative disease, primarily affecting middle-aged and elderly people. Although there is a genetic predisposition in some cases of Parkinson's disease, those with a family history might develop the disease in their youth, but sporadic cases generally occur in middle-aged or older individuals. Patients exhibit many motor symptoms that severely affect their quality of life, including muscle rigidity, limb tremors, and slowed movement, as well as other complications. Many neurologists are very familiar with Parkinson's disease and have seen many patients with it, possessing significant diagnostic and treatment experience. Therefore, consulting neurology is entirely appropriate.

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Can Parkinson's disease be cured?

Parkinson's disease is a degenerative disease of the nervous system that currently cannot be cured in medicine. It is important to choose the right treatment plan to avoid being deceived. Parkinson's disease is mainly caused by the irreversible death of dopaminergic neurons in the substantia nigra, resulting in clinical manifestations such as bradykinesia, muscular rigidity, and tremors in limbs. Other non-motor symptoms include reduced sense of smell, constipation, anxiety, depression, and orthostatic hypotension. Treatment primarily focuses on symptomatic relief, and it is not expected to achieve complete remission. Commonly used medications include levodopa, anticholinergics, and activators of levodopa and dopamine receptors. Symptoms in patients usually progressively worsen, and curing the disease is very difficult.