Early symptoms of Parkinson's disease

Written by Liu Shi Xiang
Neurology
Updated on December 03, 2024
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The early symptoms of Parkinson's disease primarily include weakness of limbs on one side, resting tremors, and bradykinesia, among others. As the disease progresses, patients will display typical Parkinson's symptoms, including a shuffling gait, reduced facial expressions, decreased sense of smell, orthostatic hypotension, anxiety and depression, cognitive decline, constipation, frequent urination, etc. Therefore, when these symptoms appear, the possibility of Parkinson's disease should be considered. Patients need to promptly visit the neurology department of a hospital for complete testing such as routine blood tests, urinalysis, MRI of the skull, and if necessary, cerebrospinal fluid analysis through lumbar puncture to confirm the diagnosis. Once diagnosed, treatment with anti-Parkinson's medication should be started as soon as possible. Commonly used medications include Levodopa, dopamine receptor agonists, monoamine oxidase inhibitors, Vitamin B6, and more.

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Written by Zhang Hui
Neurology
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What medicine is used for Parkinson's disease?

Parkinson's disease is a relatively common neurological disorder, with a higher incidence in middle-aged and elderly people. Currently, there is no specific cure for the disease, but there are many medications that can significantly improve the symptoms of Parkinson's disease. The commonly used medications mainly include: The first major category is Levodopa preparations. This type of medication has good efficacy but can cause some adverse drug reactions and may provoke the occurrence of motor complications. It should be taken under the advice of a doctor. The second major category of drugs is dopamine receptor agonists. These drugs also have relatively good effects and can improve the motor symptoms of patients, though they may be a bit expensive. Third, anticholinergic drugs. They can significantly improve the patients' normal symptoms, but should not be taken by patients with cognitive impairments. Additionally, there are monoamine oxidase inhibitors and COMT inhibitors that can also be used.

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Written by Shi De Quan
Neurology
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Does Parkinson's disease cause nausea and dizziness?

Nausea and dizziness are less common symptoms of Parkinson's disease, which primarily manifests through tremors in the limbs and head, along with paralysis symptoms such as unstable walking, lack of mobility in walking, unstable gait, and abnormal walking posture. Other non-motor symptoms may include poor sleep, depression, anxiety, and weakness. If nausea and dizziness are present, Parkinson’s disease is generally more common in elderly people and may be due to insufficient cerebral blood supply or complications such as cerebral infarction, cervical spondylosis, and high blood pressure. These causes should be ruled out before considering Parkinson's disease. While Parkinson's disease itself seldom leads to nausea and dizziness, these symptoms can also be side effects of the medications used to treat Parkinson's disease.

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Written by Zhang Hui
Neurology
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What department to see for Parkinson's disease?

Parkinson's disease is a very common degenerative neurological disorder in neurology, so if you go for treatment, you should definitely see a neurologist. Many neurologists have a high level of expertise in Parkinson's disease and have extensive experience in its diagnosis, differential diagnosis, and treatment. Patients with Parkinson's disease generally exhibit significant motor slowness, such as dressing, buttoning, wrapping dumplings, and eating very slowly, and they also walk very slowly. In addition, they may also display obvious resting tremors, muscle rigidity, general fatigue, unstable walking posture, and other clinical manifestations. Moreover, they might experience some constipation, anxiety, depression, and reduced sense of smell among other related clinical symptoms. Therefore, for this disease, visiting a neurologist is sufficient, and you can definitely expect a very satisfactory diagnosis and treatment.

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Written by Zhang Hui
Neurology
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What tests are done for Parkinson's disease?

Parkinson's disease is a degenerative disease of the nervous system. Many patients report that numerous examinations did not identify a clear cause of the disease, which is typical of this condition due to the lack of very effective diagnostic methods. Patients' symptoms gradually worsen, manifesting as motor slowness, limb tremors, muscle rigidity, and other clinical signs. There are also symptoms such as constipation and dizziness. Generally, the following examinations are recommended for Parkinson's disease: First, complete a cranial MRI scan. The primary purpose of a cranial MRI is to exclude other causes of Parkinson's-like symptoms, such as cerebral thrombosis, brain tumors, or inflammation. Second, perform olfactory tests, as some patients may experience a significant reduction in their sense of smell early on. Third, conduct induced sleep monitoring, since some patients may have prominent sleep disorders. Additionally, it is suggested to perform striatal dopaminergic transporter imaging, a type of DAT scan. Although this scan is quite expensive, it can clearly reflect the function of the striatum.

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Written by Zhang Hui
Neurology
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Can people with Parkinson's disease drink alcohol?

Patients with Parkinson's disease should not drink alcohol. This is primarily due to concerns that due to the symptoms of movement slowness and muscle rigidity, they may exhibit abnormal postural balance, greatly increasing the risk of falling. Consuming alcohol can inhibit the function of the cerebellum, exacerbating limb ataxia and increasing the risk of falling, which poses significant risks to the patient. Therefore, to protect the balance function of patients and prevent the risk of falling, they should not consume alcohol. Additionally, patients with Parkinson's disease often need to take multiple medications for their condition, and these medications should not be taken with alcohol to avoid exacerbating any adverse reactions.