How does one get Parkinson's disease?

Written by Zhang Hui
Neurology
Updated on September 05, 2024
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Parkinson's disease is a degenerative disease of the nervous system. The actual mechanism of the disease is not very clear, and its fundamental cause has not yet been identified. It is generally believed that Parkinson's disease is mainly caused by the following factors. First, genetic factors. Some cases of Parkinson's disease have a clear familial tendency, where patients may experience mutations in synaptic nuclear protein genes, leading to abnormal aggregation of these proteins. This abnormal aggregation can damage the neurons in the substantia nigra of the midbrain, leading to Parkinson's disease. Second, there are some external factors related to sporadic cases of Parkinson's. These may be closely related to oxidative stress, trauma, poisoning, or an excessive stress response of the body. However, the specific cause is not very clear. Parkinson's disease, which causes symptoms such as bradykinesia, tremors, and rigidity, requires active treatment to improve the quality of life of the patients.

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Written by Zhang Hui
Neurology
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Can Parkinson's disease be cured?

Firstly, it must be noted that Parkinson's disease is a neurodegenerative disease which currently cannot be cured. Although Parkinson's disease cannot be cured, there are many methods available to slow the progression of the disease and improve the quality of life for patients. Patients must take medication regularly under the guidance of a doctor. The treatment methods for Parkinson's disease mainly include: First, patients should strengthen their functional training and engage in as much physical activity and exercise as possible, which can help in treating the disease. Second, regular medication is necessary, mainly referring to drugs used for treating Parkinson's disease. These include dopamine receptor agonists, anticholinergic drugs, and Levodopa preparations, all of which can have good effects, but these medications also have certain side effects and require regular follow-up visits at outpatient clinics. (Specific medications should be taken under the guidance of a physician.)

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Written by Zhang Hui
Neurology
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Is Parkinson's disease scary?

Parkinson's disease is not a terrifying disease, as its onset is relatively hidden and slow, with gradual progression. Many patients can significantly improve their symptoms, prolong their lives, and enhance their quality of life through rehabilitation training and medication. However, there is no effective cure for Parkinson's disease at this time; current treatments only relieve symptoms and improve quality of life. Patients with Parkinson's should not be afraid and must regularly visit neurology outpatient clinics for follow-up. Neurologists will provide appropriate medications for Parkinson’s and guide the daily life of patients. Moreover, patients must prevent falls. Parkinson's is not a terrifying disease; what is dangerous is arbitrarily stopping or reducing medication without listening to the doctor's advice. (Note: This answer is for reference only, medication should be taken under the guidance of a professional physician, and medications should not be taken blindly.)

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Written by Zhang Hui
Neurology
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What department should Parkinson's disease go to?

Parkinson's disease is classified as a neurological disorder, so once considered for Parkinson's disease, registration is naturally in the department of neurology. Many neurologists are very familiar with Parkinson's disease and also have rich experience in diagnosis and treatment. Especially some neurology experts who specialize in Parkinson's disease have their own unique views on the pathogenesis, etiology, and clinical manifestations of the disease. Parkinson's disease is a chronic, degenerative neurological condition primarily divided into motor symptoms and non-motor symptoms, severely impacting the quality of life and work of patients. Symptoms include bradykinesia, resting tremor, muscle rigidity, etc. Treatment involves anticholinergic drugs and dopamine receptor agonists. (Note: This answer is for reference only. Medication should be administered under the guidance of a professional physician, and self-medication should be avoided.)

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Written by Zhang Hui
Neurology
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Is Parkinson's disease hereditary?

Parkinson's disease is mainly divided into two types. One type is familial Parkinson's disease, which definitely has a clear genetic predisposition. This disease is caused by mutations in some genes that lead to disruptions in some internal environments and the accumulation of abnormal proteins, eventually causing the death of neurons. Since the disease is caused by genetic mutations, there is definitely a certain genetic predisposition, and reproductive counseling is necessary to prevent the birth of offspring with Parkinson's disease. Moreover, most cases of Parkinson's disease are sporadic, and these diseases may be related to acquired factors, such as long-term mental stress, excessive pressure, brain trauma, or cerebrovascular diseases in patients, which can all lead to Parkinson's disease. This type of disease is definitely not inherited, so there is no need to worry too much.

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Written by Zhang Hui
Neurology
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Early symptoms of Parkinson's disease.

Parkinson's disease is a relatively common degenerative disease in the elderly, primarily causing the death of dopamine neurons in the substantia nigra of the midbrain, leading to corresponding clinical manifestations. Research has confirmed that other systems may also be damaged in the early stages of Parkinson's disease symptoms. The early symptoms may primarily include: First, patients experience persistent constipation, which is a very important early symptom of Parkinson's disease. Second, some patients may experience sleep disturbances, mainly characterized by tossing and turning, shouting out loud during sleep, without being aware of it. Additionally, some patients in the early stages may also experience a reduced sense of smell, constipation, cognitive impairment, and other clinical manifestations. There are also some early motor symptoms, mainly that the patient becomes clumsy and inflexible in the movements of one side of the body. These are the early symptoms of Parkinson's disease.