Early symptoms of Parkinson's disease

Written by Zhang Hui
Neurology
Updated on February 05, 2025
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Parkinson's disease in its early stages may primarily manifest as clumsiness in limb movement, especially in fine motor skills, such as difficulty in wrapping dumplings, rolling dumpling wrappers, or slow buttoning, which are clinical signs of early symptoms. Some patients may initially experience slight trembling in the limbs, which is generally more pronounced during rest and relaxation and diminishes during activity. Additionally, some individuals with early Parkinson's disease primarily exhibit non-motor symptoms, such as constipation, depression, reduced sense of smell, and may also experience rapid eye movement sleep behavior disorder, characterized by shouting and physical actions like punching or kicking during sleep.

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Written by Zhang Hui
Neurology
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Early symptoms of Parkinson's disease.

Parkinson's disease is a relatively common degenerative disease in the elderly, primarily causing the death of dopamine neurons in the substantia nigra of the midbrain, leading to corresponding clinical manifestations. Research has confirmed that other systems may also be damaged in the early stages of Parkinson's disease symptoms. The early symptoms may primarily include: First, patients experience persistent constipation, which is a very important early symptom of Parkinson's disease. Second, some patients may experience sleep disturbances, mainly characterized by tossing and turning, shouting out loud during sleep, without being aware of it. Additionally, some patients in the early stages may also experience a reduced sense of smell, constipation, cognitive impairment, and other clinical manifestations. There are also some early motor symptoms, mainly that the patient becomes clumsy and inflexible in the movements of one side of the body. These are the early symptoms of Parkinson's disease.

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Written by Zhang Hui
Neurology
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Can Parkinson's disease be cured?

Parkinson's disease is a degenerative disease of the nervous system that currently cannot be cured in medicine. It is important to choose the right treatment plan to avoid being deceived. Parkinson's disease is mainly caused by the irreversible death of dopaminergic neurons in the substantia nigra, resulting in clinical manifestations such as bradykinesia, muscular rigidity, and tremors in limbs. Other non-motor symptoms include reduced sense of smell, constipation, anxiety, depression, and orthostatic hypotension. Treatment primarily focuses on symptomatic relief, and it is not expected to achieve complete remission. Commonly used medications include levodopa, anticholinergics, and activators of levodopa and dopamine receptors. Symptoms in patients usually progressively worsen, and curing the disease is very difficult.

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Written by Shi De Quan
Neurology
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Does Parkinson's disease cause nausea and dizziness?

Nausea and dizziness are less common symptoms of Parkinson's disease, which primarily manifests through tremors in the limbs and head, along with paralysis symptoms such as unstable walking, lack of mobility in walking, unstable gait, and abnormal walking posture. Other non-motor symptoms may include poor sleep, depression, anxiety, and weakness. If nausea and dizziness are present, Parkinson’s disease is generally more common in elderly people and may be due to insufficient cerebral blood supply or complications such as cerebral infarction, cervical spondylosis, and high blood pressure. These causes should be ruled out before considering Parkinson's disease. While Parkinson's disease itself seldom leads to nausea and dizziness, these symptoms can also be side effects of the medications used to treat Parkinson's disease.

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Written by Zhou Yan
Geriatrics
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Is massage effective for Parkinson's disease?

The treatment of Parkinson's disease is comprehensive, with medication being the core method. Surgical treatments can supplement medication, and it is also important to include physical rehabilitation and psychological therapy. When patients have their symptoms and signs controlled by medication, massage can be administered to enhance their motor abilities and coordination, improving symptoms and slowing the progression of the disease. Massage therapy, therefore, has proven to be somewhat effective in this respect.

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Written by Zhou Yan
Geriatrics
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What is the best way to exercise for Parkinson's disease?

Patients with Parkinson's disease should undergo comprehensive treatment and full management. Drug treatment is the core treatment plan, but it is also necessary to include physical rehabilitation and psychological therapy. For physical therapy, patients should be encouraged to exercise more, as this can help improve symptoms and slow the progression of the disease. The type and intensity of exercise should be chosen based on the patient's motor symptoms. Tai Chi, jogging, brisk walking, and aerobics are all suitable forms of exercise, and it is advisable to exercise four times a week, with each session lasting about 30 minutes. Evidence has shown that Tai Chi can improve patients' balance disorders, and long-term persistence in exercise can help improve their quality of life.