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Gastric cancer
Early manifestations of gastric cancer
The early signs of gastric cancer may include nausea, vomiting, or mild acid reflux, which are symptoms similar to those of gastritis, stomach ulcers, or duodenal ulcers. Therefore, initially, these patients may not take their condition seriously, assuming they might just have gastritis or peptic ulcers. These are some of the early manifestations of gastric cancer, and some patients may also experience discomfort and a feeling of fullness after eating.
Late-stage symptoms of gastric cancer
The common late-stage symptoms of gastric cancer patients include nausea, vomiting, and even a complete inability to eat. There are also symptoms related to the digestive tract such as pain in the upper abdomen and acid reflux, as well as upper gastrointestinal bleeding, such as vomiting blood and melena which are signs of lower gastrointestinal bleeding. Late-stage gastric cancer patients may also experience organ metastasis, leading to corresponding symptoms. For example, metastasis of gastric cancer to the liver can cause abdominal pain and ascites due to hepatic metastatic tumors. Clinical manifestations caused by such metastatic tumors also include metastasis to retroperitoneal lymph nodes in the abdominal cavity, a common site of spread for gastric cancer. Patients may even show symptoms of intestinal obstruction, such as abdominal pain, bloating, nausea, vomiting, inability to pass stool, or even absence of flatus, which are indicators of intestinal obstruction. Consequently, patients might experience weight loss and deteriorate into a cachectic state, marked by poor nutrition and significant weight loss, which are characteristic symptoms of late-stage patients.
What are the symptoms of stomach cancer?
Symptoms of gastric cancer, especially in the early stages, generally include nausea, vomiting, loss of appetite, discomfort or bloating in the upper abdomen, pain, and acid reflux as some of the gastrointestinal symptoms, as well as vomiting blood and black stools. Black stools are tar-like stools, and their occurrence indicates bleeding in the upper gastrointestinal tract. Additionally, if the tumor causes pyloric obstruction, the patient will vomit food eaten the night before, be completely unable to eat, and experience a significant weight loss. In even more advanced stages, gastric cancer patients may develop a cachectic state.
How to treat advanced gastric cancer?
The treatment for advanced gastric cancer is primarily chemotherapy, especially for patients with peritoneal or retroperitoneal lymph node metastasis, or distant organ metastasis such as to the liver or lungs. The treatment primarily involves chemotherapy, specifically choosing either multi-drug intravenous combination chemotherapy or oral monotherapy, such as oral chemotherapy with tegafur capsules, or broad-spectrum targeted therapies like apatinib that inhibit angiogenesis. The choice of treatment depends on a comprehensive consideration of the patient's overall condition. If the patient's general condition is particularly poor and the chemotherapy risk is assessed to be high, then the approach for such advanced-stage patients is primarily the best symptomatic supportive treatment to alleviate suffering as much as possible. Therefore, the treatment plan must be determined based on a comprehensive consideration of the specific situation.
Can stomach cancer be cured?
Whether gastric cancer can be cured depends greatly on the stage at which it is discovered. Clinically, if there is no recurrence or metastasis within five years, it is considered cured. The treatment of gastric cancer is primarily surgical. Therefore, for early-stage gastric cancer patients, if a surgeon assesses that curative surgery is feasible, it is recommended to perform a radical surgical resection. For stage I gastric cancer patients, the five-year survival rate after surgical treatment can generally reach over 90%, which is quite effective. However, for those with advanced gastric cancer, it is generally incurable. Treatments, including chemotherapy, targeted therapy, or optimal symptomatic supportive care, aim to alleviate the patient's suffering and extend their life, but generally cannot cure advanced gastric cancer.
What are the symptoms of gastric cancer?
The symptoms of gastric cancer patients are generally common gastrointestinal symptoms such as nausea, vomiting, acid reflux, and discomfort and bloating in the upper abdomen, especially aggravated after eating. As the condition progresses, symptoms may include vomiting blood or black stools. When the cancer invades surrounding organs, clinical symptoms such as abdominal effusion, abdominal distension, and pain may occur. If the tumor is located near the pylorus and causes pyloric obstruction, symptoms of pyloric obstruction will appear, such as gastric retention, acid reflux, and vomiting of overnight food. Additionally, if the tumor bleeds, it may cause severe vomiting of blood. Therefore, different stages of the disease present different symptoms. If gastric cancer progresses to the late stage with metastasis to distant organs, clinical manifestations corresponding to the sites of metastasis will also appear.
How is gastric cancer treated?
The treatment methods for gastric cancer include surgery, chemotherapy, and radiotherapy, as well as broad-spectrum targeted therapies against angiogenesis, such as apatinib. Immunotherapy is also an option. However, the specific treatment plan is based on a comprehensive consideration of various factors, including the stage of the cancer and the general condition of the patient. The principle is that for early-stage gastric cancer patients, if the surgeon assesses that surgery is feasible, then radical surgical treatment is primarily used. For advanced-stage patients who are in generally good condition, chemotherapy is the main treatment, combined with a consideration of whether to undergo radiotherapy. For those in very advanced stages, who may not be in good health or those who have had chemotherapy with poor results, anti-angiogenic drugs like apatinib can be chosen as a subsequent treatment.